Scomber japonicus (chub mackerel): 128381129 Help Entry 128381129         CDS       T09718                                  Symbol pkd1a Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism sjo  Scomber japonicus (chub mackerel) Brite KEGG Orthology (KO) [BR:sjo00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:sjo03037]     128381129 (pkd1a)    04812 Cytoskeleton proteins [BR:sjo04812]     128381129 (pkd1a)    04040 Ion channels [BR:sjo04040]     128381129 (pkd1a)    04091 Lectins [BR:sjo04091]     128381129 (pkd1a) Cilium and associated proteins [BR:sjo03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    128381129 (pkd1a) Cytoskeleton proteins [BR:sjo04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     128381129 (pkd1a) Ion channels [BR:sjo04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    128381129 (pkd1a) Lectins [BR:sjo04091]  C-Type lectins   Others    128381129 (pkd1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PLAT PKD_channel Polycystin_dom LRR_8 PKD_3 LRR_4 WSC Lectin_C GPS Motif Other DBs NCBI-GeneID:  128381129 NCBI-ProteinID:  XP_053197057 LinkDB All DBs Position 2:29397792..29458994 Genome browser AA seq 4648 aa AA seqDB search MPCENGQTLSKRKHGVCVPRFSFFSSLLLALCCLEVWGSGPQGDDGRSCNPCPVNCSCAL AGPQPSCVVNCSNIGLERAPAAADIPLATNVLDLSKNRISSLDTSLLDRLTGLQELYLQE NKISVLPRGVLCCGPLSIVNLSHNHITTIEERICDNLCNLTQIDLSFNPFECDCKLFPLV SWLQEKGVRVRRPDAMLCNHPPELRNQPLLNVSLLTCGPNYAACLKDSSSGGGERSELVI FSSSTPGNLTREQCNSVCFAASHRYGGLGAKHECLCSTNSEPNFISKSQCSAACTDDHVM KECGWTMARDVFAVNFSISLKPLPLQSVHDCIGFTAASSVTPVTLSWDFGDLSSRVNTTI TTATHKYGLPGRYAVSLMAWAGHKEVSARGEVIVTLPPKLELRCPPLAVANKSLELTLVS WGAVGVDVDWKIRKDDVQIAKASPYCPMDGVYHAESSRCFQIFPVELSWTDAGQQCSERG GDLAVVRSDELRVLLAHKVTQDRGVWLGLSDPPGKLRISPMCMSLDRGAQTSSHPCNAKR AYVCQYSPQVHVKDAGIYMVGLAVFPSHNPLHRVTNTPLSAAQTPGSTIEVLLFPALSFV QAGRLSSLEFVTQEFSSEIHVRFQTYRPECHYPGLHLLLPSCGSLACAPVAVCVPNDTRD SEPRSCARLEQWCPFQRRCLALSSPCQPSSCPNCTQGHHLPPGALRPRYVLQNEVVFTLP AGSAAHVLVQDQLEDLLVSRGDIIALQHDAGPASLLRCQTSSHSLWRQPILALNQSEWFS INNTRQSTDSSADHDTDALPDPQLDVEALVEDGEGGWLEDAVCPIRVLYVGHSETQLVGT QLSAGLPQPGLYNLLVTSAEPSYPASASCLLRVVPPLGLTILHPSPRNGTLYLQPNNTRL LLRVQSRYITKAFRRSSNHNVTFQPDCPPEFSSSPALCQPGPNSGSGVEIAEQSLYAVLD LNLGEEEQRGPVQVELEAHNNVTEASLTVIVHLEKPLRELVVQPHPTHRVLMESVVSYTA SVLEGSNPTFKWTVDDKPYFTYYNTVLNVIYQHAAVYKLTVTAMNHVSTLTEHFNVTVDR LQPMANLTVKGVPDVVPQGSTQTLTTSVLVDMSVTATFRWSFGDGGYKEFEFKPPYASSF LCPDSPNQVLLSNNITYIYSQPGIYTALVSVSNRYGNISQSINMSVYSILTRVDIQTEPQ LLLANKSAEFEAHPLPSPYGIHYDWHFGDGSALLQGRRVAHTYAQSGVFNICVSVNNTIS STEACAEMFVYEEIEDLTAESSSPTELHSPTTVRAHLASGNNITWTFSMGDGKIYTPSEP HVSHSYMKEGNYTVNVTAANAVSSGWTILTVQVFVFQVVRMEPSGCVQERTLVYFQASVS GNASAHLYEWSFGDGSPNETHHGNPRVSHTYWTNGNYHLSLLLSSGVNKATKANFFNWVC VQPVLTNISLTHGKSHYAVKEEIRFQVTAEPAFNYSYQWDFDREEDVELIRGSGNMVTTY KNPGRYIVTVTVFNNISTSNTSVLIEVQMPIGPIVIQHNGTKYNNLTLRAPYAFTTSSSA SDITYTWNLGDGNVLTGQNILHTYNFSGNYNITLTAANTISRNHTVLPIAVLAPIRGLTV NASLINVPLNGSVHFEAQMEDGDGVRYSWILCGSCTSIPGTHTMFYTFRSVGTFNITVTA ENDVGTAQASIFLFVQRELEGLQILTEEESGGDGGMGLDGCCFATNRVLHLQAGLKEGTN MTFTWNLIREQDPTSSIFNISGKTVDAHFSTPGPCDIFLRAANLLGQLSVNRTIHFLEPA GRVYLQISNNPVAINAPTNLTVLTMEGSDLHYRWSVDGDTLPGTKPWMTHSFTSPGLKQV TVEAFNKVSSKLVSKTVDVQEIISELRFTATNVTEKSYVATGVSVSLQGEVQTGTNVTWT WLMEGRTVTGRKTSLIFQEPKTATVTLNATNDVSGQVVSREFFIQDKIQGLDLRASKNIV EVGEKVEFTISMAAGTDVCLSLSISGDFTVIRQLNHTYVHTFTRVDTYMVNLTAQNKVSS KTRNLQVEVMEPVRGLSIQGWCAAIPVGVKRAFVANIKTGKPVHFLWTFDLHHLHKGSHI GKEVSYTPEEAGVLTIYLKALNALHSQNITKYIVVQNRLTSAALYAEPRDTFINKKVTLM ASVTPRSNHPQTVIECLWDFGDDSTQVHTNTTTVGYKYRHPGHYSVKVNCSNQVSSVSAE VEVNISVLECEEPEVQVVRAPRLAIWRSQSTLVEASVDLKGCVRYGAQYLWQVLSTPSCD NDKDHRVASGVVTQPSQSVAVPVIRLPMEVDVRRLQLSLPKMALAAGNYTLVFSLSYEGV PLRKAACLQLSVMAARLMPIIEGGTYRVWSRTQDLQLSAEQSYDPNMDPDSQSRLHYHWE CQSTSKGPEHCSSLNFDQRFQVLDPVLGISGSELEAGVEYTFKLTISKDGMPPESTKQTV LVQSGDIPMVYLECVSCKAQSIYEVSHNSYVYLRGTCTNCQDLDRGRWSAKTLQNETLVL DSSTTTTGSGGMNLVLRKGILRHGDSYIFTLYVTDGSLDGEGAASITLHHNMPPTGGNCQ LRGGGEAGMDYGDGDSGGWRIRTLVDRVHFNCSGYSDLGISETPLLYSLLVMRCKEDYCE DFCVYKGSSPEHSAFLPPGFSSAQHRVTVFITVEDHQGAAVTAFNDTIEVVLPDLPREYT SIPHWLAELTDSKLKKMLEQGDSQRVRELSLALITVLNEYEQTREAVRRSLADRGYRVRV RSNITRALTALDLTTVNDIQQTSAALAQCTAVSREFICEECQNSTLNKLESMLEILQTDT KQGTVTPTEIADNILNIMGDLIHQVSQSASQSYIQPAYLDSPSASSTSPFTSSGEEQGGI LLDPSPSSLEPHPLRVAAKAFSLSSALMLILMHARVLNEEPLMLRGAEIAATGKLADPQS LLCYDGNNSPECQRFSIPRAFNKSLDRAAAGNSIMQLLFQVDSNPFPFNYVANYTISTEV ASMEFRTENGTQIPISGLDDSLAITVAINNGSSGEVGAEGSGAGGILTAGAVNISYCNSV IVTVSTGNNNRQAGLFVQLNFTSLEDARERDKREEEDEEPYITAYLHSHQPNEFNCTDKK RITLSMTRGQDLDHRKYTFFLSPELYDTTLDYFINVSTSCGPTSRPVGVRLEVGVFASLC QYFSKSEKQWRTDGMVPLAETNASRAVCRTRHLTAFAAGLFVPNNAISFKVTERSGPPDM VVLLVCVVGLICYVVAAAILHKLDQLDLRRAGVVPLCGRDGLFKYEVQVKTGWSRGAGTT AHVGINLYGRESRSGHRHLDSRGAFTRNALDIFHIATDTSLGSVWKIRIWHDNKGLSPAW LLQYVLVKDLQTGSSYYFLAEEWLSVDNKRTDGRVEIEVEASEEEVLRQFPRLLWCELQR ALCESHLWLSLWERPPRSPFTRLQRATCCAVLLQLFLLANTLWYNIVVDKGHSLRNVPSL NGETVAAGVVTCLIAYPLYLLVFTLFRMSRSKCVSVEQVPPQVDQESVEIDDFLDNSMAG SSFLFFNGETNSEETNVDLPTPSTKSMESWDMAEEETEDRDWPELLSDVSVVGGAGHGAG LPRLKRGQGSRHLGVDMTFNPDEEEGTEQRNKYFTSSDEDLIKHILTDGQNFFPQADESE MADLSSIFGDKTEVILLQKLNEPLPLESVRRDPPKTAFTSNTVVTDVCRPRRFPPWCGRA ALWGSWAGIALANCISIMASRGFSERVALMWLISCFASFLCSCLLLEPIKVLCEAVYYAV CVRRLRPEDQDVLVEFPRVERVVQRVHRVRPPQGFALSQARHQARKVHMLHTMLKNFLVY MFFLLVVLLLNYSDSAKDAHSLRLRTQLQRAIHTPEYHNISSRDDVLVWLNESLLPRLLD DSALLRDTGSVLLGTLRLRQIRDMQVAGGLRSADSIWEQGWVTSPTKDAENVTALGVADA NCQMVVSNSGDLVLQLNRSLEEASSSLQQLRQLHWLNYRTHAVYVEFSLYNINTNLLAVF SFLFEFPVSERAQSSLDLLVVTLWPITGLDLQLLLMIVLLALVLYFLVRGILGFLGEGYM YLLSAWRLLGICKLALSASVCGLHLSRCIMAKQQWASYLKHPQDAFTDFYPLAKQSQMYT VMSAMLLFILVLKASHQLRFLREWAVFGRALRRSVWELLGVALALLLLVLAYSHTGHLLF HSVFDGYGSVSSACMSLLGTGGRGLLSWRPAWTITGPSSTVSSLMFHASFAVLRLVLLWL VTSVLLRNYRRARAELYRPAVDLQDYEMVELFLRRLKMWMGLSRTKEFRHKVRFEGMELP PSRSSSTSDCKSLCLPPLDGPDSPPTPDSVDAGSEASWRPASSSPCSLTEAPGIGLGLGL GLGLGLSPGVVVGGTSWRERAETEASLRRLLPTLDALLQQLDRVTMATEDLYHIECRLER AQRKRRRRGRERGGGQGGRSEAGQRGKGEDKDRKSGKEKHKGSKKGKKTDKSELPKDCGN TATNLKKTPVATPVPFLKPRPASASTQTSALQSSVKSSVTDKSASDSSSLPVSSTSALPP HVQPPKTTTAPPCTPAPTTSLPSTPAPTPISRDWDPPTERETLPSSSLFNHPAHTTTIPT RKRKRKPPPLKNKVHPNLDRHGPGHPKP NT seq 13947 nt NT seq  +upstreamnt  +downstreamnt atgccttgtgaaaatggacagactttatccaagcgaaaacatggcgtctgcgtcccgagg tttagtttcttttccagtctgctactggcgctctgctgtctggaggtatggggctccggg ccgcagggagacgacggcaggagctgcaacccctgtcccgttaactgcagctgcgctctg gcggggccccagccgtcctgcgtcgtcaactgctccaacatcgggctggagagggcccca gctgcggccgacatcccgctggccaccaacgtgctagatctgtccaagaatcgcatctct tcccttgatacaagtctgctagaccgtctcactggcctccaagagctgtatcttcaagag aacaagatcagtgttctcccaaggggggttttgtgctgtgggccgctgtcaattgtcaat ttgagccacaaccatatcaccaccatagaagaaagaatatgtgacaacttatgcaattta actcaaattgacctgagctttaacccctttgaatgtgactgtaagctgttcccgttggtc agctggctccaggagaaaggggtgcgagttcgacggccagatgccatgctctgtaaccat cctcctgagttacgcaaccagcctttgctcaacgtcagcctgctcacctgtggaccgaat tatgcagcttgtctcaaggacagcagcagtggaggaggggaacggagcgagcttgtcatc ttctcttcctccacaccgggcaacctcacacgtgaacagtgtaacagtgtgtgttttgct gcatcgcatcgctatggaggcttgggggcgaaacacgagtgtctctgcagcacaaactct gagccaaacttcatcagcaaatctcagtgttctgctgcctgtacagatgatcatgttatg aaggaatgtgggtggactatggcccgtgatgtgtttgcggtgaacttctccatctcgctg aagcctctcccactacaaagtgttcacgactgtatcggtttcactgccgcctcctctgtc actccagtaacattgtcatgggactttggtgacctttcatctcgggtcaacactacaatc accacagcaacacacaaatacggacttccaggacgatatgcggtcagtttgatggcctgg gctggacacaaggaggtctctgcacgcggggaggtgattgtgacacttcctcccaaactg gagctgcgctgtccacctcttgctgtggccaataagagtcttgagttgactcttgtcagc tggggtgctgttggagtggatgtagactggaagatcagaaaagatgatgtccagattgcc aaagcctctccttattgtccaatggatggggtgtaccacgccgagtcctcacgctgtttc cagatttttccagtagagctgagctggaccgatgctggacagcagtgttcagagcgtggt ggggatctggcagtagtcagaagtgacgagctgcgtgtcctgctggcacataaagtcaca caggatcggggtgtgtggctgggcttgagtgaccctccaggcaagctgcggatctccccc atgtgtatgtcacttgatcggggtgctcagaccagttcacacccatgcaacgccaagcga gcctatgtctgccagtacagcccccaagtgcatgttaaagatgcagggatctacatggtg ggactggctgtgtttccctcccataatcctttgcaccgtgtcaccaacactccactctct gctgcacaaacacccggcagcaccatagaggtactgctgttcccggcactgagctttgtt caagcaggtcgtctgtcctccctggagtttgtcactcaggagtttagctcagaaatccac gtccgattccagacctacagacctgaatgtcattatccaggcctgcacctgctgctgccc agttgtggaagtctagcgtgtgctccagtggctgtatgtgtccccaatgacaccagggac agtgagccacgttcttgtgcccgactagagcagtggtgtcctttccagcgtcggtgcctg gccctctccagtccttgccagccatcgtcctgtcctaattgcacccagggtcaccacctg cctcctggggcgctaagaccccgatacgtgctccagaatgaggtggtcttcacgctacca gcgggatcagctgcacatgtactggtgcaagaccaattagaagacctcctggtttcccgc ggcgacatcattgccctgcagcatgatgccggccccgcctccctcctccgctgccaaacc tcctcgcactcactgtggcgacaacctattttagcccttaatcagtcagagtggttttcg attaacaacaccagacagtcaacagacagctcagctgaccacgacactgacgccctacct gaccctcagctcgacgtagaggcgctggtggaggatggcgaggggggctggctggaggat gcagtgtgccccatcagagtgctctatgtgggacacagtgagacgcaactggtgggaaca cagctgtctgctggtctaccccagcctggactctacaacctgctggtgacttctgctgag ccgtcatacccagcctcagcatcatgcctgttgcgagtggtgcctcctctgggtttgacg atcctccacccctctcccaggaatggcaccctttacctgcagcccaacaacacccggcta ctgctccgtgtccagtctcgctacataacaaaggcatttcggcgcagcagtaatcacaat gtgaccttccagcctgactgtcccccagagttttcatccagcccagcactctgtcagccc ggaccaaactcggggtcaggggttgagatcgcagagcaaagcctgtatgcagtgcttgat ctgaacctgggggaagaggagcaaaggggtccagtgcaggtggagttagaggctcacaat aacgtgacagaagccagcctgactgtgattgtccacctggaaaagccactcagagaattg gtggtgcagccacaccctacccacagggtgttgatggagtcagttgtgagttatacagca tcagtgcttgaaggctctaatcccacatttaaatggacagttgatgacaagccctacttc acttattacaacactgtcctcaatgtgatctaccagcacgctgccgtctacaagctcaca gtgacagctatgaaccatgtcagcaccctcacagagcatttcaacgtcacagtggatcga ctgcagcccatggccaacctcacagtaaagggtgttccagatgtggtccctcagggctcc actcagactctcaccacctctgtgctcgtggacatgtctgtgaccgccaccttccgatgg tcttttggtgatgggggatacaaggagtttgaattcaagcctccctacgcctcctccttc ctctgcccagactctcccaatcaggtcctcctcagcaacaacatcacctatatctactca cagccaggaatatacacagcgctggtgtcagtttccaatcgttatgggaacatcagtcag agcatcaacatgagtgtctacagcatcctcactcgtgtcgatatacagactgagccccaa cttctcctagctaacaaatcagcagagtttgaggctcatcctttaccctcaccttatggc attcactatgactggcactttggagatggctctgccctgctgcaaggtagacgagtggca cacacctatgcacagagtggtgtgttcaatatctgtgtatcagtgaacaacactatcagt tctacagaggcttgtgccgagatgtttgtatatgaggagattgaagatttaacagctgaa agttcctctccgacagagcttcacagccccactacagtgcgggcacaccttgcttctggt aacaatatcacatggacattctccatgggtgatgggaagatctacactccatctgaacct cacgtgtcacacagctatatgaaagaaggcaactacacagtgaacgtgactgctgccaat gctgtgagttctggctggacgatcttaacagtgcaggtatttgttttccaagtggtgagg atggagccgtctggatgtgtccaagaaaggacgctcgtatacttccaggcctcggtgtcc ggtaacgcatcagctcatctctatgagtggagctttggggacgggagccccaatgagaca caccatggcaaccccagagtctcacacacctactggacaaatgggaactatcacctctcc cttcttctctccagcggagtcaacaaggctaccaaggccaacttcttcaactgggtatgt gtccagccagttttaaccaacatcagccttacccatgggaaatcgcactatgctgtcaag gaggagatacggttccaggtcacagctgaaccagcatttaactatagctatcagtgggac tttgacagagaggaagacgttgaactcattcgtggttctggaaatatggtgacaacgtat aaaaacccaggtcgatacatagtgacagtaacggtcttcaataacatctccacaagtaat actagtgttctgattgaggttcagatgcccataggaccaattgttattcaacataatggc actaagtacaataacttgacacttagagcaccgtatgcttttaccacttcttcctcagcc tctgatattacttacacctggaacctaggagatgggaacgtgcttacaggccagaatatc ctccacacctacaatttctctggaaactacaatattactctgacagccgccaatacaatt agcaggaatcacactgttttacccattgctgtccttgcacctatccgtggactcaccgtc aacgccagcttgataaatgtccctctcaatggctcagtccactttgaggcccaaatggaa gacggagatggtgtccggtactcttggatcttgtgtggcagctgcacctcaatcccaggc acccacaccatgttttacacattccgctctgttggcactttcaacatcactgtgacagcg gagaatgatgtaggaacagcacaagctagtatctttctgtttgttcaacgtgagctggag gggctgcagatcttaactgaggaggagagtggaggagatggaggcatgggattggatggt tgctgctttgctacaaaccgtgttctccaccttcaagcaggattgaaggaaggaaccaat atgacctttacttggaacctcatcagagagcaagaccctaccagctcaatcttcaacata agcgggaaaaccgtggacgctcatttctctaccccaggtccatgtgacatctttctccgg gctgccaacctcctgggccagctgtctgtcaacagaaccatccacttcctggagccagct ggaagggtatacctgcagatcagcaacaacccagttgcgatcaatgctccaactaatctg acagtactgactatggagggctcagacttgcattaccgctggtctgttgatggggacact ctgcctggaaccaagccctggatgacacacagctttactagtcctggcctaaaacaagtg actgtagaggccttcaataaagttagctcaaagcttgtgtcaaagacagtagatgtccag gaaataatttctgagctgagattcactgcaaccaatgtgacagagaagagttacgtagct accggtgtcagtgtctcactccaaggggaggtacagactggaaccaatgtgacctggaca tggctgatggaaggaagaacagtaacaggaaggaaaacttctctgattttccaggagccg aaaacagcaactgttactttgaatgccaccaacgatgtcagtgggcaagtggtttccagg gagttctttattcaggacaagattcaggggttggatctgagggcaagtaaaaacattgta gaagttggtgagaaggtggagttcaccatttctatggcagcaggtacagacgtttgtctg agcctcagcatcagcggagatttcactgttatccgtcaactcaaccacacctacgtccac acgttcaccagggtggatacatacatggtgaatctcactgctcaaaacaaggtgagttca aagacgcgaaacctgcaggtggaggtgatggagccggtgcgtggactttccatccaggga tggtgcgcagcaatccctgtaggtgtgaagagagcgtttgtggccaacatcaagacgggc aaacctgttcacttcctgtggacatttgatctacaccacctccacaagggatcacatata ggcaaagaggtgtcctacacgccagaagaagcaggggtgttgaccatttacctgaaggcc ctcaatgcactgcacagtcagaatatcaccaagtacatcgtggtgcagaaccggctgaca tctgctgccttgtatgcagaacctcgagacactttcatcaataagaaagtgaccctgatg gcctctgtcacacccagatccaatcatccacaaacagtcatagagtgtttgtgggacttt ggtgatgattctactcaagttcacacgaacaccacaactgtgggctacaagtacagacac ccaggacactactcggtcaaagtgaactgcagtaaccaggtgagctcggtatcagccgag gtggaggtaaacatcagtgtattagagtgtgaggaaccagaggtacaggtggttcgggcc ccccgcctggccatctggcgttcccagtccacattggtggaggccagtgtggacctgaag ggttgtgtgcgctacggagctcaatacctctggcaggtactctcaacgccctcctgtgat aatgacaaagaccaccgtgttgcctctggggtggtgactcaaccctcccagtcagtagct gtcccagtaattcgccttccgatggaggttgatgtgcggcggctgcagctttcattgcct aagatggctctggcagcaggaaactacaccttggtgttttctttatcatatgaaggtgtg ccgctgaggaaggctgcctgtttgcaactcagtgtcatggctgccaggctcatgcccatc atagaagggggcacctacagggtgtggtcgaggacgcaggacctgcagctcagtgcagag cagtcttacgatcccaacatggacccagacagccagtcacgactccactaccactgggag tgccagagcacttcaaagggtccagaacactgttccagtctgaacttcgaccagagattc caagtactggacccagtacttggaatctctggctccgagctggaagcaggcgtcgaatat actttcaaactgactatcagcaaagatggcatgccaccggagtccaccaaacaaactgta ctcgtccagagtggcgatattcccatggtgtatctggagtgtgtgtcctgtaaggcccag tccatctacgaggtcagccacaactcgtatgtctacctgagaggaacctgcaccaactgc caggacttggaccgtgggcgttggagtgccaagacactacagaatgagactctggtcctg gactcctccaccaccaccacaggcagtggcggcatgaatcttgtgttgcgaaagggcatc ctgcgccatggagactcttacatcttcacgctgtatgtgacagacggcagcctggatggt gagggtgccgcttctatcacgttgcaccacaatatgcccccgactggtgggaattgtcaa ctgagagggggaggggaagcaggaatggactacggggatggagacagtggaggctggagg atacgcacactggtggaccgggtacactttaactgctcaggttacagtgatctgggcatt tcagagacgcccttgctctacagtctgctggtgatgcgctgcaaagaagactactgtgaa gacttctgtgtgtacaaaggcagcagtccggagcactcggccttcctgcccccaggcttc agctcagcccaacaccgtgtaaccgtattcatcacagtagaggaccaccaaggagctgcg gtcacagcattcaacgataccatcgaggttgtgctgccagatctgccccgtgaatacacc agcattccccattggctggctgagctgacagacagcaaactcaaaaagatgctggagcaa ggagactcccagagggtcagagagttatcactggctctcattacagttctaaatgagtat gagcagacgagggaggcagtacggcggtccctagctgaccgtggttaccgagtcagagtt cgtagcaacatcaccagagctctgaccgccctggacctgaccactgttaacgacatccag cagacctccgctgctctggcacagtgcacagcagtgagccgagagttcatctgtgaggag tgtcaaaacagcactctgaacaaactggagtccatgctggagattctgcaaaccgacact aagcagggcaccgtcaccccgactgagatagctgacaatattctgaacatcatgggtgat ctgatccatcaggtcagccagtcagcctcccagtcttacatccagcctgcttacttggat tctccgtcagcctcctcaacatccccgtttacctcttctggtgaagaacaaggaggtatc ctattagacccctctccctcctccctggaaccacaccctctgcgagtggcggccaaggct ttcagcctgtcctcggccctcatgctgatcctcatgcacgcccgtgtgctcaacgaggag ccacttatgctgagaggagctgagattgccgccacgggaaaactggcagacccccagagc ctgctttgctacgatggcaacaacagtccagaatgccagcggttctccatcccccgcgct ttcaacaaaagtcttgacagagctgctgcaggaaatagcatcatgcagctactctttcag gtggattctaaccccttccccttcaactatgtggccaactacaccatctctaccgaagtg gcgtccatggagttccgcactgaaaatggcacccagattcccatctccggacttgatgat agtctagccatcactgttgccattaacaatggcagtagtggtgaagtgggtgctgagggt tctggtgccggaggcatcctcacagctggagctgtaaacatcagctactgcaactctgtc attgtcacggtcagcacaggaaataacaaccgacaggcagggctatttgtgcagctgaac ttcacctctctggaagatgccagagagagggataaaagggaagaagaggatgaggagccg tacattacagcctaccttcattctcatcaacctaatgagttcaactgcacagacaaaaaa cgtatcacactcagtatgaccagggggcaagatcttgaccacaggaaatacaccttcttt ctgtcaccagagttgtacgacactacactggactactttatcaacgtgagcacatcctgt ggacccacctctcgtcctgtgggtgttcgactagaggtcggggtgtttgcttcgctgtgt cagtacttcagtaagagcgaaaagcagtggcggacagatggcatggtacccctggcagaa accaatgccagcagagccgtttgccgcacgaggcatctcactgcctttgctgcaggtctc tttgtaccgaacaatgcaatcagctttaaagttacagagcgttctggtccaccagacatg gtcgtcctactggtgtgtgtggtgggcttgatttgctatgttgttgcggcggccatcttg cacaagttggaccagctagatttgcgccgggccggtgtggttccactctgcggccgagac ggactcttcaagtacgaggttcaggttaagactggctggagccggggtgcaggcaccacg gctcatgtgggaatcaatttgtacggacgtgaaagccgcagtggacaccgccatctcgac agcaggggagccttcacacgcaacgctcttgacatctttcatattgctacagataccagc ctgggaagtgtgtggaaaatccggatttggcatgacaacaagggcctgtccccagcgtgg ttgttacagtacgtcttggtcaaagatttgcagacaggaagcagctactacttcctggct gaggagtggctgtcagtagacaacaaaagaactgatggaagggtagagattgaggtggag gcttcagaggaggaagtgcttcgtcagtttccccgcctcctgtggtgtgagcttcagagg gcgctatgtgagagtcacctgtggctgtctctgtgggagaggcccccccgcagccccttc acccgcctgcagagagccacatgctgcgctgtgttactgcagctcttcctattagcaaac acattgtggtacaacattgtggtggataaaggtcacagcctgcggaacgtgccttcatta aatggagagacggttgcagcgggtgtggtgacctgtctgatcgcctaccctctctacctg cttgtcttcacgctttttagaatgagccgcagcaagtgtgtgtctgtggagcaggtgcca ccacaagtggaccaggagtcagtggagattgatgacttcctggacaactccatggctgga agttccttcctgttttttaatggcgagaccaattcagaagaaacgaatgtagatttgccc actccatcaactaaaagcatggagagttgggacatggcagaggaggagactgaggacagg gattggccagagctcctgagtgatgtgtctgtggtgggaggggcggggcatggagcaggt ctgcccaggctgaagaggggtcaagggagcagacatctcggtgttgatatgacctttaac cctgacgaggaggaggggactgagcaacgcaacaaatattttacttcttcagatgaggac ctgatcaaacacatcctgacagatggacagaacttctttcctcaggcagatgaaagtgag atggctgacctgtcgagtatttttggagataagacagaagtgattctccttcagaagctg aatgagcctcttcctttagaatctgtcagaagagacccaccaaaaactgctttcacctca aatacagttgtgacagatgtatgtcgtcccagacggttcccaccctggtgtggacgtgcc gccctgtggggcagctgggcagggattgctttggcgaattgtatttcaattatggcgagc cgcgggttcagtgaacgtgtggccctgatgtggctcatctcctgttttgccagcttcctg tgctcctgcctgcttttggagcccattaaggtgttgtgtgaggcagtttattacgctgtg tgtgtgcgtcgcctgcgtccagaggaccaggatgtgctagtggagtttccccgagtggag agagtagtccagcgggttcacagggtgagaccaccgcagggcttcgctctgtcccaggcc cgacatcaggcccgcaaggtccacatgctgcacaccatgctgaagaatttcctggtttat atgtttttcctgttggtggttttgcttctcaactattctgactcagccaaagatgcacac agcctgagactgcgcacgcagctgcaacgagcaatacacacacctgagtaccacaacatc agcagccgcgatgacgttctggtgtggctgaacgagtccttgttaccacgcctactggat gactccgccctcttgagagacacaggaagtgtgttactcggcacacttaggctccggcag atccgtgacatgcaggttgcaggtggtttaaggtcagcagatagtatttgggaacagggc tgggtcacatctccaactaaagatgctgagaatgtcacagctttaggtgttgccgatgcg aactgtcagatggtcgtgagtaacagtggagacttggtccttcagctcaacagaagcctg gaagaggcctcatccagcttacagcagctgcggcagctgcactggcttaactacaggacc catgcagtatatgtggaattctcactctacaacatcaacaccaaccttctggccgtcttc tccttcctgttcgagttcccggtctctgagcgtgctcagtccagccttgacctccttgtt gtcaccctgtggccaatcacaggcctggacttgcagctccttctcatgattgtcctcctc gccttggtgttgtatttcttggtgcgagggatattgggcttcctgggagagggctacatg tacttgctgtcagcttggagactcctgggcatctgtaaactggctctgtcagcatctgtg tgcgggctgcacctgagccgctgtataatggccaagcagcagtgggcatcatacctgaag cacccgcaggatgccttcactgatttctacccgctggccaaacagagtcaaatgtacaca gtcatgtctgccatgctgttgttcatactggtgctcaaggcttcccaccagttgcggttt ctcagagagtgggccgtgtttggcagagctctgcggcgttcagtctgggagctactggga gtcgctctggcgttactgctgttggtgctggcttactcacacacagggcacctgctcttc cactctgtatttgacggctatggcagtgtgagctcagcctgtatgtctctgttgggcact ggtggacgtggcctgctgtcgtggcgacctgcctggacgattactggcccctccagcacc gtctcctcgctgatgttccacgccagcttcgctgtacttcggttggtgctgctatggttg gtcacgtctgtgttgctgaggaactaccggcgtgcgcgagcagagctgtaccgtccagcc gtggatctccaagactacgagatggtcgagctgttcctcagacgactcaaaatgtggatg ggactcagcaggaccaaggagtttcgtcacaaggtccgttttgaaggcatggagctgcca ccatcccgttcatcctccaccagcgactgtaagtctctatgtttgcctccactggatggt cccgactcccctcccactccagacagtgtggatgctggctctgaagcctcatggcgcccg gcctcctccagcccctgcagcctgactgaagctccggggattggtctggggctcgggctg ggcctgggtttgggtctcagtccaggggtggtggtgggaggtaccagctggagggagaga gcagagactgaagcctccctgaggaggctgctccccactctggacgccctgctgcaacag cttgaccgtgtcaccatggcaacagaggatctgtaccacatcgagtgtaggctggagcga gcccagaggaaaaggaggcgcagagggagagagagaggcggtggccagggagggaggagt gaggcaggacagaggggaaagggggaggacaaggacagaaagagtggaaaagaaaagcac aaagggagcaagaaggggaaaaagacggataaaagtgaacttccaaaggactgcggaaac actgctaccaatctcaaaaagactcctgtagccacacctgttccctttttaaagcccaga ccagcttctgcctctacacaaacctcagctcttcagtcttcagttaaatcttcagtcaca gataaatctgcctctgattcttcttcccttcccgtttcatcaaccagcgctcttcccccc cacgtccaaccacccaaaacaaccactgcacctccatgtacccctgcacctaccacttcc ttgccatctactcctgcccctacgcccattagccgggactgggacccgccaacggaaaga gagaccctcccctcctccagcctgttcaaccacccggctcacactaccaccattcccaca cgcaagagaaaacgcaaacccccacccctcaaaaacaaggtgcaccccaatttagacaga cacgggcccgggcacccaaaaccctga

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