Streptomyces kanamyceticus: CP970_04385
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Entry
CP970_04385 CDS
T06849
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
ska
Streptomyces kanamyceticus
Pathway
ska00909
Sesquiterpenoid and triterpenoid biosynthesis
ska01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
ska00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
CP970_04385 (shc)
Enzymes [BR:
ska01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
CP970_04385 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
CP970_04385 (shc)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
QEU90240
UniProt:
A0A5J6G3R3
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All DBs
Position
complement(1175917..1177911)
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AA seq
664 aa
AA seq
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MTATTDGSTGAAPPRAASASQPLDTTAATAGTRDAAARAMQRSTDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEPTTRAAALFIRGEQRDDGTWATFFGGPGELSATIEAY
VALRLAGDRPDEPHMVKASAWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELIYF
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHADARRPNPVKPLAPVASW
DGVFQRLDKALHVYRKVAPRRVRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVLKAGLDSLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVALALRRVKHPDK
ARMENAIERGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGKSHDPRTRRGIEWLLAEQEESGAWFGRWGVNYVYGTGSVVPALVAAGLPASHR
AIRRAVSWVESVQNDDGGWGEDLRSYRERGWAGHGTSSASQTAWALLALLSAGEREAKSV
ERGIAWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFTGGS
GKGS
NT seq
1995 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggagcggccccgccccgcgcagcctcggccagc
cagccactcgacacgaccgccgcgacggcaggcacacgtgacgccgccgcgcgcgccatg
caacgctccacggatttcctgctctcccgacaggacgcccagggctggtggaagggcgac
ctcgagaccaacgtgacgatggacgccgaggacctcctcctgcggcagttcctcgggatc
agggacgagccgaccacgcgcgccgccgcgctcttcatccgcggcgagcagcgcgacgac
ggcacctgggccaccttcttcggcgggcccggcgaactctccgccaccatcgaggcgtac
gtcgcgctgcgcctggcgggcgaccggcccgacgagccgcacatggtgaaggcttccgcg
tgggtcagggagcagggcggcatcgccgcgagccgggtcttcacccgcatctggctggcc
ctcttcggctggtggaaatgggacgacctgcccgaactcccgccggagctcatctacttc
cccaagtggttcccgctcaacatctatgacttcggctgctgggcgcggcagaccatcgtg
ccgctcacgatcgtctccgccaagcggcccgtgcgccccgcgccgttcgccctggacgag
ctgcacgccgacgcgcgccgcccgaaccccgtcaaaccccttgcgccggtggcgagttgg
gacggggtcttccagcggctcgacaaggcgctgcatgtctaccgcaaggtcgcgccgcgc
cgggtgcgcaaggccgcgatgaacagcgcggcgcgctggatcatcgagcggcaggagaac
gacggctgctggggcgggatccagccgcccgccgtctactccgtgatcgccctgcacctg
ctcggctacgacctggaccacccggtcctgaaggccgggctcgactcgctcgaccggttc
gctgtgtggcgcgacgacggcgcccggatgatcgaggcgtgtcagtcgccggtgtgggac
acctgcctggcgaccatcgcgctcgcggacgccggagtgcccgccgaccacccgcagttg
gtcaaggccgcggactggatgctgggcgagcagatcgtccgccccggggactggtcggtg
cgcagaccgggactgacccccgggggctgggcgttcgagttccacaacgacaactacccc
gacatcgacgacaccgcggaagtcgccctcgcgctgcgccgggtcaagcacccggacaag
gcgcgcatggagaacgccatcgagcgcggggtgcgctggaacctcggcatgcagtcgaag
aacggtgcctggggcgccttcgacgtcgacaacaccagcgccttccccaaccgccttccg
ttctgcgacttcggcgaggtcatcgacccgccgtccgccgacgtcaccgggcacgtggtg
gagatgctcgccgtcgagggcaagtcgcacgacccgcgcacccggcgcggcatcgagtgg
ctgctcgccgaacaggaggagagcggcgcctggttcggccgctggggcgtcaactacgtc
tacggcaccgggtccgtggtgcccgcgctcgtcgccgcggggctgcccgcctcgcaccgg
gcgatccgccgcgccgtcagctgggtcgagtcggtgcagaacgacgacggcggctggggc
gaggacctgcgctcctaccgcgagcgcggctgggctgggcacggcacgtcgagcgcctcg
cagaccgcgtgggcgctgctcgcgctcctctcggccggtgaacgcgaggccaagtccgtg
gagcggggcatcgcctggctcgccgagacgcagcgcgaggacggctcctgggacgagccg
tacttcaccggtaccggcttcccctgggacttctccatcaactaccacctctaccggcag
gtgttcccgctgaccgcgctcggcaggtacgtcaacggcgagccgttcacgggcggctcc
ggcaaggggagctga
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