Streptomyces kanamyceticus: CP970_38295
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Entry
CP970_38295 CDS
T06849
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ska
Streptomyces kanamyceticus
Pathway
ska00010
Glycolysis / Gluconeogenesis
ska00020
Citrate cycle (TCA cycle)
ska00620
Pyruvate metabolism
ska00785
Lipoic acid metabolism
ska01100
Metabolic pathways
ska01110
Biosynthesis of secondary metabolites
ska01120
Microbial metabolism in diverse environments
ska01200
Carbon metabolism
ska01210
2-Oxocarboxylic acid metabolism
Module
ska_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ska00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP970_38295 (aceE)
00020 Citrate cycle (TCA cycle)
CP970_38295 (aceE)
00620 Pyruvate metabolism
CP970_38295 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP970_38295 (aceE)
Enzymes [BR:
ska01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP970_38295 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
QEU96002
UniProt:
A0A5J6GNM5
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All DBs
Position
complement(8785669..8788413)
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AA seq
914 aa
AA seq
DB search
MFHITELARNSRVRERGSPVSQLDQLPDQDPTEVAEWRASLDGAVRFGGADRAAHLLRRL
AEHALQTGIDLPPLLETPYVNTIPTAAEPDFPGDEAMEARIAAWNRWNAAAMVTRGNQRG
GLGGHMATFASAAWLYEVGFQHFFRGKEADHSGDQLYVQGHASPGIYARAFLEGRLTEGQ
LDRFRQEAGGAGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLEHRGIKDTSA
SHVWAFLGDGEMDEPEATAALALASREKLDNLTFVINCNLQRLDGPVRGNFKIVQELERQ
FRAAGWNVVKSLWGSAWDELLAQDTDGALVRQLGRIPDGQFQTFAARDGAYVREHLLGAD
PALRPLADRLTDARLAEIVGTSRGGHEPRKVYAAYRAAVEHRGAPTVVLIQTVKGWTLGP
GFESRNANHQMKKLSGKEFRAMRDLLELPIPDSALTDDLVPYAHPGENSPELAYLLERRA
ALGGPAPARKVVAKPLPATGSAVADKAFAALKKGSGSQEIATTMAFVRLVKELMRDKETG
GRWVPIVPDEARTFGMESLFPSAGIYSPLGQTYDPVDRDQLLYYKEARDGQILNEGITEA
GSLASLTAAATSYATHAEPMIPFYIFYSMFGWQRTADQFWALGDQLGRGFVIGATAGRTT
MTGEGLQHADGHSHLIASTNPAAISYDPAFAYEVAVIVEDGLRRMFGPDAEDVFYYLTVY
NETKVQPPMPPGDDVAEGIRRGLYRYRAADAAPADAPRLQLLASGTAIHWALEAQRLLTE
DWGVAADVWSAPSWTELRRDALDCDAANLAAASHDTGASDRVPYVTRALAGAPGPVVAVS
DWMRAVPDQIRPWVEQDWTSIGTDGYGLSDSRENARRHFGVDAPSVVVAALASLARRGEV
KPETVREAAARYGL
NT seq
2745 nt
NT seq
+upstream
nt +downstream
nt
atgttccacatcacggaactcgcgcggaactcgcgtgtacgcgaaaggggatcacccgtg
tcccagctcgaccaactgcccgaccaggacccgaccgaggtcgccgaatggcgcgcgtcc
ctggacggcgccgtccggttcgggggcgccgaccgcgcggcccacctgctgcgccgcctc
gccgagcacgccctgcagaccgggatcgacctcccgcccctgctggagacgccctacgtc
aacaccatccccaccgccgccgaaccggacttccccggtgacgaggcgatggaggcccgc
atcgccgcgtggaaccgctggaacgcggccgcgatggtgacgcgcggcaaccaacgcggc
gggctcggcggccacatggccaccttcgcctcggccgcctggctctacgaagtgggcttc
cagcacttcttccgcggcaaggaggccgaccactcgggcgaccagctctacgtccagggc
cacgcatcccccggcatctacgcccgcgccttcctcgaaggacgcctgaccgagggccag
ttggaccgcttccggcaggaggcgggcggcgccggactgccctcctacccgcacccgagg
cggctgccctggctgtgggagttccccaccgtgtcgatgggcctcggcccgctctccgcc
atctaccaggcgcggttcaaccgctacctggagcaccgcggcatcaaggacacctccgcc
tcgcacgtctgggcgttcctcggcgacggcgagatggacgagcctgaggcgaccgcggcc
ctcgcgctcgcctcccgcgagaagctcgacaacctcaccttcgtcatcaactgcaatctg
cagcgcctggacggcccggtgcgcggcaacttcaagatcgtgcaggagctggagcggcag
ttccgcgccgcgggctggaacgtggtcaagtccctgtggggctcggcctgggacgagctg
ctcgcccaggacaccgacggggcactcgtacgacagttggggcggatcccggacgggcag
ttccagacgttcgccgcccgcgacggcgcgtacgtccgcgagcacctcctcggcgcggac
cccgcgctgcgcccgctggccgaccggctcaccgacgcgcgcctcgcggagatcgtcggc
acctcgcgcggcggccacgagccccgcaaggtgtacgccgcctaccgcgccgcggtggaa
caccggggcgcgcccacggtcgtcctgatccagacggtcaagggctggacgctcggcccc
ggcttcgagtcgcgcaacgccaaccaccagatgaagaagctctcgggcaaggagttccgc
gcgatgcgcgacctgctcgaacttcccatccccgacagcgcgttgaccgacgacctggtg
ccgtacgcgcatcccggcgagaactcccccgagctggcctatctgctcgaacggcgcgcg
gcgctcggcggccccgccccggcccgcaaggtcgtcgccaagccgctgcccgccaccgga
tccgccgtcgccgacaaggcgttcgcggcgctgaagaagggctcggggagccaggagatc
gccaccaccatggcgttcgtccggctggtcaaggagctgatgcgggacaaggagaccggc
gggcgctgggtgcccatcgtgcccgacgaggcgcgcacgttcggcatggagtcgctgttc
ccgtccgcgggcatctactcgccgctcggccagacctacgaccccgtcgaccgcgaccag
ctcctctactacaaggaggcgcgcgacggccagatcctcaacgagggcatcacggaggcc
ggttcgctggcctcgctgaccgcggcggcgacgtcgtacgcgacccacgccgagccgatg
atcccgttctacatcttctactcgatgttcggctggcagcggacggccgatcagttctgg
gcgctgggcgaccagttgggccgcggcttcgtcatcggggccacggcggggcgtacgacg
atgacgggcgagggtctccagcacgccgacgggcactcgcatctgatcgcctcgaccaat
ccggccgccatcagctacgacccggcgttcgcctacgaggtcgcggtgatcgtcgaggac
ggcctgcgcaggatgttcgggcccgacgccgaggacgtcttctactacctcaccgtctac
aacgagacgaaggtccagccgccgatgccgccgggcgacgacgtcgcggagggcatccgg
cgcggcctgtaccgctaccgggcggccgatgccgcacccgccgacgccccgcgcctgcag
ctcctggcctccggcacggccatccactgggctcttgaggcacagcggctgctcaccgag
gactggggcgtcgcggccgacgtctggtcggcaccgtcctggaccgaactccgccgcgac
gcactggactgcgacgccgcgaacctcgccgccgcctcccacgacacgggcgcgagcgac
cgggtcccgtacgtcacccgggccctcgcgggcgcccccgggcccgtggtcgcggtgagc
gactggatgcgtgccgtgcccgaccagatcaggccgtgggtcgagcaggactggacctcg
atcggcacggacggctacggcctctccgacagccgcgagaacgcccgccgccacttcggc
gtcgacgcgccctcggtcgtggtcgccgccctggcgtccctcgcccgccgcggcgaggtc
aagccggagacggtgcgggaggccgccgcacgctacggcctgtag
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