Streptomyces koelreuteriae: KJK29_04185
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Entry
KJK29_04185 CDS
T09603
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
skg
Streptomyces koelreuteriae
Pathway
skg00909
Sesquiterpenoid and triterpenoid biosynthesis
skg01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
skg00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
KJK29_04185 (shc)
Enzymes [BR:
skg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
KJK29_04185 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
KJK29_04185 (shc)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Mago-bind
Motif
Other DBs
NCBI-ProteinID:
QWB21837
UniProt:
A0ABX8FLB0
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All DBs
Position
complement(934300..936333)
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AA seq
677 aa
AA seq
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MTATTDGSTGALPPRAAAASEHDTDIPAAAGVPEAAARAARRATDFLLSRQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQRDDGAWATFYRGPGELSATIEAY
VALRLAGDAPDAPHMARASAWIRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELVWF
PKWMPLNIYDFGCWARQTIVPLTIVSAERPVRPAPFPLDELHTDPATPNPAKPLAPMVSW
DGAFQRMDKGLHALRKVAPRRLRRAAMNSAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVILALRRITHHDP
ERLEKAIGRGLRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHHPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
AIRRAVTWLESVQNDDGGWGEDLRSYHDVKEWSGKGASTASQTAWALMALLAAGERDSKA
VERGVEWLAATQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFADR
HQGSGEAARPYSKAKGS
NT seq
2034 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggccctgccaccccgcgccgccgcggccagc
gaacacgacaccgacatccccgcggcggccggggtaccagaagccgccgcacgcgccgcc
cggcgtgccaccgacttcctgctctcccgccaggacgccgagggctggtggaagggcgac
ctcgagaccaacgtcacgatggacgccgaggacctgctgctccgtcagttcctcggcatc
cgcgacgagaagaccacccgggccgccgctctcttcatccgcggcgagcagcgcgacgac
ggcgcctgggcgaccttctaccgcggccccggcgagctctccgccaccatcgaggcctac
gtagccctccgcctggcgggcgacgcgcccgacgcgccccacatggccagggcctcagcc
tggatccgcgagcggggcggtatcgccgccgcccgggtcttcacccggatctggctcgcg
ctgttcggctggtggaagtgggaggacctgcccgaactcccgccggagctcgtctggttc
ccgaagtggatgccgctcaacatctacgacttcggctgctgggcccggcagaccatcgtc
ccgctgacgatcgtctccgccgagcggcccgtacgccccgcgcccttcccgctcgacgag
ctgcacaccgacccggccaccccgaaccccgccaagccccttgcgccgatggtcagttgg
gacggcgccttccagcgtatggacaagggcctgcacgccctgcggaaggtcgccccgcgc
cggctgcgcagagccgccatgaacagcgccgcccgctggatcgtcgaacggcaggagaac
gacggctgctggggcggcatccagccgcccgccgtgtactcgatcatcgccctgcacctg
ctcggctacgacctccagcaccccgtgatgcgggaggggctggcgtccctggaccggttc
gccgtgtggcgtgaggacggggcccggatgatcgaggcctgccagtcgccggtctgggac
acctgcctcgccgcgatcgcgctcgccgacgccggactgcccgccgaccacccccagttg
gtgaaggcggcggactggatgctgggcgaggagatcgtcagacccggcgactggtccgtc
aaacggccccaacttccgcccgggggctgggcgttcgagttccacaacgacaactacccc
gatatcgacgacaccgccgaggtgatcctggcgctccgccggatcacccaccacgacccg
gagcggctggagaaggccatcgggcgcggactgcgctggaccctcggcatgcagtcgaag
aacggcgcgtgggccgccttcgacgtcgacaacacgagccccttcccgaaccggctgccg
ttctgcgacttcggcgaggtcatcgacccgccctccgccgacgtcaccgcgcacgtcgtc
gagatgctcgcggtggagggactcgcccaccacccgcgcacccggcgcggcatcgaatgg
ctgctggccgaacaagagccggacggctcgtggttcgggcgctggggcgtcaactacgtc
tacggcaccggatccgtcgtacccgccctggtcgccgcgggcctgcccgccgcgcacccg
gcgatccggcgggccgtgacctggctggagtcggtccagaacgacgacggcggctggggc
gaggacctgcgctcctaccacgacgtcaaggagtggagcggcaagggcgcctcgaccgcc
tcccagaccgcgtgggccctgatggccctgctcgcggcgggggagcgggactccaaggcc
gtcgaacgcggcgtcgaatggctcgccgccacccagcgggccgacggctcctgggacgag
ccgtacttcaccgggacgggcttcccgtgggacttctcgatcaactaccacctctaccgg
caggtgttccccctcaccgcgctcggccgctacgtccacggggagcccttcgccgaccgg
caccaggggagcggggaggccgcgaggccgtactccaaggccaaggggagctga
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