Streptomyces koyangensis: D0C37_27845
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Entry
D0C37_27845 CDS
T06436
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sky
Streptomyces koyangensis
Pathway
sky00270
Cysteine and methionine metabolism
sky00450
Selenocompound metabolism
sky00670
One carbon pool by folate
sky01100
Metabolic pathways
sky01110
Biosynthesis of secondary metabolites
sky01230
Biosynthesis of amino acids
sky04980
Cobalamin transport and metabolism
sky04981
Folate transport and metabolism
Module
sky_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sky00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
D0C37_27845 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
D0C37_27845 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
D0C37_27845 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
D0C37_27845 (metH)
04980 Cobalamin transport and metabolism
D0C37_27845 (metH)
Enzymes [BR:
sky01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
D0C37_27845 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
AXQ58038
UniProt:
A0A385DI48
LinkDB
All DBs
Position
6220521..6224045
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AA seq
1174 aa
AA seq
DB search
MASSPTHRTALSAAARADALREALATRVVVADGAMGTMLQAQDPTLDDFQQLEGCNEILN
LTRPDIVTSVHDAYFAVGVDCVETNTFGANHAALGEYDIPERVFELSEAGARVARESADR
FTVETGQQRWVLGSMGPGTKLPTLGHAPYTTLRDAYQRNAEGMIAGGADALLIETTQDLL
QTKASVIGARRALEATGANLPVIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCA
TGPAEMSEHLRHLARHSRVPISCMPNAGLPVLGKDGAHYPLTAPELADAQENFVREYGLS
LVGGCCGTTPEHLRQVVERVRGAVPGARDPRPEPGAASLYQTVPFRQDTSYLAIGERTNA
NGSKKFRTAMLEGRWDDCVEMAREQIREGAHLLDLCVDYVGRDGVADMTELAGRFATAST
LPLVLDSTEVDVLRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTALAQEHGAALMALTI
DEEGQARTTEHKVAVAERLIEDLTGNWGIHESDILIDTLTFTICTGQEESRKDGVHTIEA
IRELKRRHPDVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIAR
LEEEHVKVALDLIHDRRAEGYDPLQTFLELFEGVDTKSMKAGKAEELLALPLDERLKRRI
IDGEKNGLHEDLDEALTERPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKDA
VAYLEPHMEKAEGDEEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSA
ILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLASGYPVILGGAALTRAYVEQDL
HEIYEGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRVRATASATVTEEPEEGP
VRSETATDNPVPTPPFWGTRVAKGIPLKDYASWLDEGALFKGQWGLKQNRAGDGPSYEEL
VETEGRPRLRGWLDELHTRNLLEAAVIHGYFPCVSKGDDLIVLDDAGNERTRFSFPRQRR
GKRLCLADFFRPEESGETDVVGFQVVTVGSRIGEATAELFAANSYRDYLELHGLSVQLAE
ALAEYWHARVRAELGFGGEDPVDVEDMFALKYRGARFSLGYGACPNLEDRAKIADLLQPE
RIGVHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3525 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgtcgccgacccatcggaccgcactctccgccgccgcccgcgcggacgccctc
cgcgaagcactggccacccgggtggtggtcgcggacggggcgatgggcacgatgctccag
gcgcaggaccccaccctcgatgacttccagcagctcgaaggctgcaacgagatcctcaac
ctcacccggccggacatcgtcacctccgtccacgacgcctacttcgcggtgggggtcgac
tgcgtcgagaccaacaccttcggtgccaaccacgcggcgctgggggagtacgacatcccc
gagcgggtcttcgagctctccgaggcaggggcccgggtcgcccgcgagagcgccgaccgc
ttcaccgtcgagaccggccagcagcgctgggtgctcggctcgatgggccccggcaccaag
ctgccgaccctgggccacgccccgtacaccacgctgcgcgacgcctaccagcggaacgcc
gagggcatgatcgccggcggcgccgacgcgctgctgatcgagaccacccaggacctgctc
cagaccaaggcgtcggtgatcggcgcccgccgcgccctggaggcgaccggcgccaacctg
ccggtcatcgtctcggtcaccgtcgagaccaccggcaccatgctgctcggctcggagatc
ggggccgcgctcaccgcgctggagccgctgggcatcgacatgatcggcctgaactgcgcg
accggccccgccgagatgagcgagcacctgcgccacctcgcccgccactcgcgcgtcccg
atctcctgcatgcccaacgccggtctgcccgtcctcggcaaggacggcgcgcactacccg
ctgaccgcccccgagctggccgacgcccaggagaacttcgtccgcgagtacggcctctcc
ctggtgggcggctgctgcggcaccacccccgagcacctgcgccaggtcgtggagcgcgtg
cggggagccgtccccggcgcgcgggacccgcgccccgagccgggcgccgcctcgctctac
cagacggtgccgttccgccaggacacctcgtacctggcgatcggcgagcggaccaacgcc
aacggctccaagaagttccgcacggcgatgctggagggccgctgggacgactgcgtggag
atggcgcgcgagcagatccgcgagggcgcccacctgctggacctctgcgtcgactacgta
ggccgcgacggcgtcgccgacatgacggaactggccgggcggttcgccaccgcctccacc
ctgccgctggtcctcgactccaccgaggtcgacgtgctccgcgccgggctggagaagctg
ggcggacgcgccgtcatcaactccgtcaactacgaggacggggacggccccgagtcgcgg
ttcgccaaggtcaccgcgctggcccaggagcacggcgcggccctgatggcgctgaccatc
gacgaggagggccaggcccgtaccaccgagcacaaggtggccgtggccgagcggctgatc
gaggacctgaccggcaactggggcatccacgagtcggacatcctcatcgacaccctgacc
ttcaccatctgcaccggtcaggaggagtcccgcaaggacggcgtgcacaccatcgaggcg
atccgcgagctgaagcgccgccaccccgacgtgcagaccacgctgggcctgtccaacatc
tccttcgggctcaacccggccgcccgcatcgtcctcaactccgtcttcctcgacgagtgc
gtcaaggccgggctcgactcggcgatcgtgcacgcctccaagatcctgccgatcgcccgg
ctggaggaggagcacgtcaaggtcgccctcgacctcatccacgaccgccgcgccgagggg
tacgacccgctccagacgttccttgagctcttcgagggcgtcgacaccaagtcgatgaag
gccggcaaggccgaggaactcctcgctctcccgctggacgagcggctcaagcgccgcatc
atcgacggcgagaagaacggcctgcacgaggacctggacgaggcgctgaccgagcggccc
gccctggacatcgtcaacgacaccctgctggacggcatgaaggtggtcggcgagctgttc
ggctccggccagatgcagctgcccttcgtcctccagtccgccgaggtcatgaaggacgcg
gtggcttacctggaaccgcacatggagaaggccgagggcgacgaggaggggaagggcacc
atcgtgctcgccaccgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatc
atcctctccaacaacggctacaacgtcgtcaacctcggcatcaagcagcccgtctccgcc
atcctggaggccgccgaggagcaccgcgccgacgtcatcggcatgtccggactcctcgtc
aagtccacggtgatcatgaaggagaacctggaggagctgaaccagcgcggcctggcctcc
ggctaccccgtcatcctcggcggcgccgccctcacccgcgcctacgtcgagcaggacctc
cacgagatctacgagggggaggtccgctacgcccgcgacgccttcgagggcctgcgcctg
atggacgccctcatcgccgtcaagcgcggcgtccccggcgccaccctccccgagctgaag
cagcgcagggtgcgggccaccgcctccgccacggtgaccgaggagcccgaggagggcccg
gtccgctccgagaccgccaccgacaacccggtccccaccccgccgttctggggcacccgc
gtcgccaagggcatcccgctcaaggactacgcctcctggctcgacgagggcgctctcttc
aagggccagtggggcctgaagcagaaccgcgccggcgacggtcccagctacgaggaactg
gtcgagaccgagggccgcccccggctgcgcggctggctggacgagctgcacaccaggaac
ctgctcgaagccgccgtcatccacggctacttcccctgcgtcagcaagggcgacgacctc
atcgtgctcgacgacgcgggcaacgagcggacccgcttcagcttcccccgccagcgccgg
ggcaagcggctctgcctcgccgacttcttccgcccggaggagtccggcgagaccgatgtg
gtcggcttccaggtcgtcaccgtcggctcccgcatcggcgaggccaccgccgaactgttc
gccgccaactcctaccgcgactacctcgaactccacggcctctccgtgcagctcgccgag
gccctcgccgagtactggcacgcccgcgtccgcgccgagctgggcttcggcggggaggac
ccggtggacgtcgaggacatgttcgccctgaagtaccgcggcgcccgcttctcgctcggc
tacggcgcctgcccgaacctggaggaccgcgccaagatcgccgacctgctccagcccgag
cggatcggcgtgcacctctcggaggagttccagctccaccccgagcagtccaccgacgcg
atcgtcatccaccaccccgaggccaagtacttcaacgcgcgctga
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