KEGG   Streptomyces koyangensis: D0C37_27845
Entry
D0C37_27845       CDS       T06436                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
sky  Streptomyces koyangensis
Pathway
sky00270  Cysteine and methionine metabolism
sky00450  Selenocompound metabolism
sky00670  One carbon pool by folate
sky01100  Metabolic pathways
sky01110  Biosynthesis of secondary metabolites
sky01230  Biosynthesis of amino acids
sky04980  Cobalamin transport and metabolism
sky04981  Folate transport and metabolism
Module
sky_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:sky00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    D0C37_27845 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    D0C37_27845 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    D0C37_27845 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    D0C37_27845 (metH)
   04980 Cobalamin transport and metabolism
    D0C37_27845 (metH)
Enzymes [BR:sky01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     D0C37_27845 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: AXQ58038
UniProt: A0A385DI48
LinkDB
Position
6220521..6224045
AA seq 1174 aa
MASSPTHRTALSAAARADALREALATRVVVADGAMGTMLQAQDPTLDDFQQLEGCNEILN
LTRPDIVTSVHDAYFAVGVDCVETNTFGANHAALGEYDIPERVFELSEAGARVARESADR
FTVETGQQRWVLGSMGPGTKLPTLGHAPYTTLRDAYQRNAEGMIAGGADALLIETTQDLL
QTKASVIGARRALEATGANLPVIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCA
TGPAEMSEHLRHLARHSRVPISCMPNAGLPVLGKDGAHYPLTAPELADAQENFVREYGLS
LVGGCCGTTPEHLRQVVERVRGAVPGARDPRPEPGAASLYQTVPFRQDTSYLAIGERTNA
NGSKKFRTAMLEGRWDDCVEMAREQIREGAHLLDLCVDYVGRDGVADMTELAGRFATAST
LPLVLDSTEVDVLRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTALAQEHGAALMALTI
DEEGQARTTEHKVAVAERLIEDLTGNWGIHESDILIDTLTFTICTGQEESRKDGVHTIEA
IRELKRRHPDVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIAR
LEEEHVKVALDLIHDRRAEGYDPLQTFLELFEGVDTKSMKAGKAEELLALPLDERLKRRI
IDGEKNGLHEDLDEALTERPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKDA
VAYLEPHMEKAEGDEEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSA
ILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLASGYPVILGGAALTRAYVEQDL
HEIYEGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRVRATASATVTEEPEEGP
VRSETATDNPVPTPPFWGTRVAKGIPLKDYASWLDEGALFKGQWGLKQNRAGDGPSYEEL
VETEGRPRLRGWLDELHTRNLLEAAVIHGYFPCVSKGDDLIVLDDAGNERTRFSFPRQRR
GKRLCLADFFRPEESGETDVVGFQVVTVGSRIGEATAELFAANSYRDYLELHGLSVQLAE
ALAEYWHARVRAELGFGGEDPVDVEDMFALKYRGARFSLGYGACPNLEDRAKIADLLQPE
RIGVHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3525 nt   +upstreamnt  +downstreamnt
atggcctcgtcgccgacccatcggaccgcactctccgccgccgcccgcgcggacgccctc
cgcgaagcactggccacccgggtggtggtcgcggacggggcgatgggcacgatgctccag
gcgcaggaccccaccctcgatgacttccagcagctcgaaggctgcaacgagatcctcaac
ctcacccggccggacatcgtcacctccgtccacgacgcctacttcgcggtgggggtcgac
tgcgtcgagaccaacaccttcggtgccaaccacgcggcgctgggggagtacgacatcccc
gagcgggtcttcgagctctccgaggcaggggcccgggtcgcccgcgagagcgccgaccgc
ttcaccgtcgagaccggccagcagcgctgggtgctcggctcgatgggccccggcaccaag
ctgccgaccctgggccacgccccgtacaccacgctgcgcgacgcctaccagcggaacgcc
gagggcatgatcgccggcggcgccgacgcgctgctgatcgagaccacccaggacctgctc
cagaccaaggcgtcggtgatcggcgcccgccgcgccctggaggcgaccggcgccaacctg
ccggtcatcgtctcggtcaccgtcgagaccaccggcaccatgctgctcggctcggagatc
ggggccgcgctcaccgcgctggagccgctgggcatcgacatgatcggcctgaactgcgcg
accggccccgccgagatgagcgagcacctgcgccacctcgcccgccactcgcgcgtcccg
atctcctgcatgcccaacgccggtctgcccgtcctcggcaaggacggcgcgcactacccg
ctgaccgcccccgagctggccgacgcccaggagaacttcgtccgcgagtacggcctctcc
ctggtgggcggctgctgcggcaccacccccgagcacctgcgccaggtcgtggagcgcgtg
cggggagccgtccccggcgcgcgggacccgcgccccgagccgggcgccgcctcgctctac
cagacggtgccgttccgccaggacacctcgtacctggcgatcggcgagcggaccaacgcc
aacggctccaagaagttccgcacggcgatgctggagggccgctgggacgactgcgtggag
atggcgcgcgagcagatccgcgagggcgcccacctgctggacctctgcgtcgactacgta
ggccgcgacggcgtcgccgacatgacggaactggccgggcggttcgccaccgcctccacc
ctgccgctggtcctcgactccaccgaggtcgacgtgctccgcgccgggctggagaagctg
ggcggacgcgccgtcatcaactccgtcaactacgaggacggggacggccccgagtcgcgg
ttcgccaaggtcaccgcgctggcccaggagcacggcgcggccctgatggcgctgaccatc
gacgaggagggccaggcccgtaccaccgagcacaaggtggccgtggccgagcggctgatc
gaggacctgaccggcaactggggcatccacgagtcggacatcctcatcgacaccctgacc
ttcaccatctgcaccggtcaggaggagtcccgcaaggacggcgtgcacaccatcgaggcg
atccgcgagctgaagcgccgccaccccgacgtgcagaccacgctgggcctgtccaacatc
tccttcgggctcaacccggccgcccgcatcgtcctcaactccgtcttcctcgacgagtgc
gtcaaggccgggctcgactcggcgatcgtgcacgcctccaagatcctgccgatcgcccgg
ctggaggaggagcacgtcaaggtcgccctcgacctcatccacgaccgccgcgccgagggg
tacgacccgctccagacgttccttgagctcttcgagggcgtcgacaccaagtcgatgaag
gccggcaaggccgaggaactcctcgctctcccgctggacgagcggctcaagcgccgcatc
atcgacggcgagaagaacggcctgcacgaggacctggacgaggcgctgaccgagcggccc
gccctggacatcgtcaacgacaccctgctggacggcatgaaggtggtcggcgagctgttc
ggctccggccagatgcagctgcccttcgtcctccagtccgccgaggtcatgaaggacgcg
gtggcttacctggaaccgcacatggagaaggccgagggcgacgaggaggggaagggcacc
atcgtgctcgccaccgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatc
atcctctccaacaacggctacaacgtcgtcaacctcggcatcaagcagcccgtctccgcc
atcctggaggccgccgaggagcaccgcgccgacgtcatcggcatgtccggactcctcgtc
aagtccacggtgatcatgaaggagaacctggaggagctgaaccagcgcggcctggcctcc
ggctaccccgtcatcctcggcggcgccgccctcacccgcgcctacgtcgagcaggacctc
cacgagatctacgagggggaggtccgctacgcccgcgacgccttcgagggcctgcgcctg
atggacgccctcatcgccgtcaagcgcggcgtccccggcgccaccctccccgagctgaag
cagcgcagggtgcgggccaccgcctccgccacggtgaccgaggagcccgaggagggcccg
gtccgctccgagaccgccaccgacaacccggtccccaccccgccgttctggggcacccgc
gtcgccaagggcatcccgctcaaggactacgcctcctggctcgacgagggcgctctcttc
aagggccagtggggcctgaagcagaaccgcgccggcgacggtcccagctacgaggaactg
gtcgagaccgagggccgcccccggctgcgcggctggctggacgagctgcacaccaggaac
ctgctcgaagccgccgtcatccacggctacttcccctgcgtcagcaagggcgacgacctc
atcgtgctcgacgacgcgggcaacgagcggacccgcttcagcttcccccgccagcgccgg
ggcaagcggctctgcctcgccgacttcttccgcccggaggagtccggcgagaccgatgtg
gtcggcttccaggtcgtcaccgtcggctcccgcatcggcgaggccaccgccgaactgttc
gccgccaactcctaccgcgactacctcgaactccacggcctctccgtgcagctcgccgag
gccctcgccgagtactggcacgcccgcgtccgcgccgagctgggcttcggcggggaggac
ccggtggacgtcgaggacatgttcgccctgaagtaccgcggcgcccgcttctcgctcggc
tacggcgcctgcccgaacctggaggaccgcgccaagatcgccgacctgctccagcccgag
cggatcggcgtgcacctctcggaggagttccagctccaccccgagcagtccaccgacgcg
atcgtcatccaccaccccgaggccaagtacttcaacgcgcgctga

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