Streptomyces laculatispora: P8A22_04075
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Entry
P8A22_04075 CDS
T09657
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
slai
Streptomyces laculatispora
Pathway
slai00909
Sesquiterpenoid and triterpenoid biosynthesis
slai01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
slai00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
P8A22_04075 (shc)
Enzymes [BR:
slai01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
P8A22_04075 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
P8A22_04075 (shc)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
DUF6894
Motif
Other DBs
NCBI-ProteinID:
WLQ39276
UniProt:
A0ABY9HXH0
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All DBs
Position
complement(1006381..1008384)
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AA seq
667 aa
AA seq
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MTATTDGSPGAVDPRAASASRPTTESTTAADDVLAAARRAAERSVEHLLGKQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDSATVQAAGRFIRGEQLGDGTWATFHGGPGDLSATIEA
YVALRLAGDRPQDPHMVRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPGEPNPARPPAPAAS
WDGVFQRLDKALHLYHRIAPRRVRRLAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLDHPVMRAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPA
LVKAADWMLDEEIARPGDWSVRRPQLSPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
PARIEAAIERGVRWNVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGHSANPVTRRGIEWLLAEQDVAGGWFGRWGVNYVYGTGSVVPALVAAGLPAAH
PSIRRAVQWLESVQNDDGGWGEDLRSYNEDKWIGHGASTASQTAWALLALLAADRRDTTA
VARGVAWLTGTQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TAVREGA
NT seq
2004 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagccccggggctgtggatccccgcgcagcctcggccagt
agaccgacaaccgaatcaaccaccgccgcggacgacgtactggccgccgcgcggcgggcc
gcggaacgctcggtggagcatctcctcggcaagcaggacgagcagggctggtggaagggc
gacctcgccaccaacgtcaccatggacgccgaggacctcctgctccgccagttcctcgga
atccaggattccgccacggtccaggcggccggccgcttcatccgcggcgagcagctcggt
gacggcacctgggccacgttccacggcggccccggggacctctccgccaccatcgaggcg
tacgtggcactgcggctggccggtgaccggccgcaggacccgcacatggtccgtgccgcg
gggtgggtcagggaacagggcggaatcgcggcgagccgggtgttcacccggatctggctg
gccctgttcggctggtggaaatgggacgacctgccggagctcccgcccgagctgatgttc
ttccccaagtgggtcccgctcaatatctacgacttcggctgctgggcccgccagaccatc
gtgccgctcacggtcgtctccgcgaagcggccggtccggcccgcccccttcgcgctggac
gagctgcacaccgacccgggcgaaccgaacccggccaggccccctgctccggcggccagt
tgggacggtgtcttccagcgcctcgacaaggcgctgcacctctatcaccggatcgccccg
cgcagagtccgccgtctcgccatgaacgcggccgcccgctggatcatcgaacgccaggag
aacgacggctgctggggcgggatccagccgcccgccgtctactccgtcatcgcgctgcac
ctgctgggctacgacctcgaccacccggtgatgcgggccggactcgcctcgctggaccgg
ttcgcggtctggcgcgaggacggcgcccgcatgatcgaggcctgccagtccccggtctgg
gacacctgtctcgccaccatcgcgctcgccgacgccggagtgagccccgatcacccggcg
ctcgtgaaagcggcggactggatgctcgacgaggaaatcgcccggccgggcgactggtcg
gtgcgcaggccccaactctccccgggcggctgggcgttcgagttccacaacgacaactac
cccgatatcgacgacaccgcggaggtggtcctcgcgctgcgccgggtccgccacccggat
ccggcacggatcgaggccgccatcgagcggggggtgcgctggaacgtcggcatgcagtcc
cgcaacggcgcctggggagcgttcgacgccgacaacaccagcccgttccccaaccggctg
cccttctgcgacttcggcgaggtcatcgacccgccgtccgcggacgtcaccgggcacgtg
gtggagatgctcgccatcgagggccattccgcgaaccccgtcacccggcgtggcattgaa
tggctgctcgccgaacaggacgtcgcaggcggctggttcggccggtggggcgtcaactac
gtgtacggaacagggtcggtggtgcccgcgttggtcgccgccggactgcccgcggcgcat
ccctcgatccgccgcgcggtccaatggctggagtccgtccagaacgacgacggcggctgg
ggcgaggacctgcgctcgtacaacgaggacaagtggatcggccacggagcctcgaccgcg
tcccagacggcctgggcgctgctcgcactcctcgccgcggaccggcgggacaccacggcc
gtggcccgcggggtcgcctggctcaccgggacccagcaggccgacggctcctgggacgag
ccgtacttcaccggtaccggcttcccctgggacttctccatcaactaccacctctaccgg
caggtcttcccgctgaccgcactcgggcggtatgtccacggcgaccccttcgccggccgc
accgccgtccgtgagggggcctga
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