Streptomyces laculatispora: P8A22_28320
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Entry
P8A22_28320 CDS
T09657
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
slai
Streptomyces laculatispora
Pathway
slai00010
Glycolysis / Gluconeogenesis
slai00020
Citrate cycle (TCA cycle)
slai00620
Pyruvate metabolism
slai00785
Lipoic acid metabolism
slai01100
Metabolic pathways
slai01110
Biosynthesis of secondary metabolites
slai01120
Microbial metabolism in diverse environments
slai01200
Carbon metabolism
slai01210
2-Oxocarboxylic acid metabolism
Module
slai_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
slai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
P8A22_28320 (aceE)
00020 Citrate cycle (TCA cycle)
P8A22_28320 (aceE)
00620 Pyruvate metabolism
P8A22_28320 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
P8A22_28320 (aceE)
Enzymes [BR:
slai01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
P8A22_28320 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF5817_CT
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
WLQ43481
LinkDB
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Position
complement(6374671..6377340)
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AA seq
889 aa
AA seq
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MTDPVGKLPSELDQLPDRDPEETAEWAASLDAVTKAAGPHRAAYLMRRSLQHAEGAGLAL
PKLLETDYVNSIPTAAEPAFDGDLAMESRITAWNRWNAAAMVTRGSRLGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLSEQQLDNFRQEAGGEG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRNIKDTSNSHVWAFLGDGEM
DEPESTAALALAAREQLDNLTFVINCNLQRLDGPVRANFRVVQELEGAFRGAGWNVVKTL
WGNAWDELFQLDTTGALVRRLREVPDAQFQTYATRDVAYIRQHFFGAEPALAELAKLLTD
AKIAECFHTSRGGHEARKVYAAYKAAVEHKGAPTVILAQTVKGYTLGPGFESRNANHQMK
KLDGKQFRAMRDLLELPIPDSKLDEGLVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
AVALPQPEERAFSALKKGSGKQELATTMAFVRLAKDLMRDKETGKRWVPIVPDEARTFGM
EALFPSAGIYSPLGQTYDPVDRDQLMYYKEAKDGQVLNEGITEAGAMADFIAASTSYATH
GEPMIPFYIFYSMFGWQRTGDQFWQLGDQLGRGFVVGATAGRTTLTGEGLQHADGHSHLI
ASTNPASLNYDPAFAYEIAVIVQDGLRRMYGPDAENVFYYLTVYNEPKPQPAMPEGVEEG
IVKGLYRFKEGAPATADAPRLQLMASGTAIHWALEAQELLAADWGVTADVWSATSWGELR
REALECDEALLRGEHRVPYVTQALEGAPGPVLAVSDWMRAVPDQISQWVEQDWSSLGTDG
FGLSDTREAARRHFGVDAQSVTVAALAQLARRGEVTASAVKEARERYGL
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccgtaggaaagcttccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgaatgggcggcctccctcgacgccgtcaccaaggccgcaggcccgcac
cgcgccgcatacctgatgcgccgctcgctccagcatgccgagggcgccggtctcgcgctg
cccaaactgctggagaccgattacgtcaactccatcccgaccgccgccgagcccgcgttc
gacggcgacctggcgatggagtcccggatcaccgcctggaaccgctggaacgcggccgcg
atggtcacccgtggctcccggctcggcgtcggcggccacatcgccaccttcgcctcggcg
gcctggctgtacgagaccggcttcaaccacttcttccgcggcaaggagggggacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatatacgcccgcgccttcctg
gacggccggctcagcgagcagcagctcgacaacttccgccaggaggcgggcggcgagggc
ctgccgtcctacccgcacccgcggcgactgccctggctgtgggagttccccaccgtgtcg
atgggtctcggcccgctctcggcgatctaccaggcgcgcttcaaccgctacctgaccaac
cgcaacatcaaggacacgtcgaactcgcacgtctgggccttcctgggcgacggcgagatg
gacgagcccgagtcgaccgccgccctcgccctcgcggcccgtgagcagctcgacaacctg
accttcgtcatcaactgcaacctgcagcggctcgacggtccggtccgcgccaacttccgg
gtggtccaggagctggagggcgcgttccgcggcgccggctggaacgtcgtcaagacgctc
tggggcaacgcctgggacgagctgttccagctcgacaccacgggcgcgctggtgcgccgg
ctcagggaggtcccggacgcgcagttccagacgtacgccacccgcgacgtcgcctacatc
cggcagcacttcttcggcgccgagcccgctctcgccgagctggcgaagctgctcaccgac
gcgaagatcgccgagtgtttccacacctcgcgcggtggccacgaggcccgcaaggtgtac
gcggcgtacaaggccgcggtcgagcacaagggtgcgccgaccgtgatcctcgcgcagacg
gtgaagggctacacgctcggcccgggcttcgagtcgcgcaacgccaaccaccagatgaag
aagctcgacggcaagcagttccgtgccatgcgcgatcttctggagctgccgatcccggac
tcgaagctggacgagggcctggtgccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgtgccgccctcggcggccccgccccggcccgccgggtgcac
gcggtggccctgccgcagcccgaggagcgcgcgttcagcgcgctgaagaagggctccggc
aagcaggaactggccaccacgatggcgttcgtccgcctggccaaggacctgatgcgggac
aaggagaccggcaagcgctgggttccgatcgtcccggacgaggcccgcaccttcggtatg
gaggcgctgttcccgtcggccggcatctactcgccgctgggccagacgtacgacccggtc
gaccgcgaccagctgatgtactacaaggaagccaaggacggccaggtcctcaacgagggc
atcaccgaggccggcgcgatggccgacttcatcgccgcttccacgtcgtacgcgacgcac
ggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcagcgtacgggc
gaccagttctggcagctgggcgaccagctcggccgcggcttcgtggtcggtgccacggcg
ggccgcacgaccctcacgggcgagggcctccagcacgcggacggtcactcgcacctgatc
gcgtccacgaacccggcgtcgctcaactacgacccggcgttcgcgtacgagatcgcggtg
atcgtccaggacggtctgcgccggatgtacggccccgacgccgagaacgtcttctactac
ctgacggtctacaacgagccgaagccgcagcccgcgatgccggaaggcgtcgaggagggc
atcgtcaagggcctctaccgcttcaaggagggcgcgcccgcgacggcggacgcgccgcgc
cttcagctgatggcgtccggtacggcgatccactgggccctggaggcccaggagctgctg
gccgcggactggggtgtcacggccgacgtctggtccgccacctcgtggggcgagctgcgc
cgggaggcgctggagtgcgacgaggcgctgctccgcggcgagcatcgggtgccgtacgtg
acccaggcgctggaaggcgcaccgggtccggtcctcgcggtcagcgactggatgcgcgcg
gtgccggaccagatcagccagtgggtggagcaggactggtcctcgctcggtacggacggc
ttcggcctctccgacacccgcgaggctgcccgccgccacttcggtgtcgacgcgcagtcg
gtgaccgtcgcggcactggcccagctggcccgccgtggtgaggtgaccgcgtcggcggtc
aaggaggcccgcgagcggtacgggctctga
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