Streptomyces laurentii: SLA_1776
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Entry
SLA_1776 CDS
T05205
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
slau
Streptomyces laurentii
Pathway
slau00010
Glycolysis / Gluconeogenesis
slau00020
Citrate cycle (TCA cycle)
slau00620
Pyruvate metabolism
slau00785
Lipoic acid metabolism
slau01100
Metabolic pathways
slau01110
Biosynthesis of secondary metabolites
slau01120
Microbial metabolism in diverse environments
slau01200
Carbon metabolism
slau01210
2-Oxocarboxylic acid metabolism
Module
slau_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
slau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SLA_1776
00020 Citrate cycle (TCA cycle)
SLA_1776
00620 Pyruvate metabolism
SLA_1776
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SLA_1776
Enzymes [BR:
slau01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SLA_1776
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
BAU82714
UniProt:
A0A160NX50
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Position
1879976..1882687
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AA seq
903 aa
AA seq
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MTDPVGKIPSELDQLPDRDTEETAEWAASLDAVTKAAGPHRAAYLMRRTLQHAEGAGLAL
PKLLETDYLNTIPTSAEPVIDGDEEMERRITAWNRWNAAAMVTRGAKHGVGGHIATFASA
AWLYETGFNHFFKGKDAKDAPGSGDQLYIQGHASPGIYARAFLDGRLSEDHLDNFRQEAG
GNGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRSIKDVSASHVWAFLGD
GEMDEPEATAALALAAREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVV
KTLWGNAWDELFALDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGKDPALVAMAQL
LSDDKILECFHLSRGGHEPRKVYAAYKAALEFKGAPTVILAQTVKGFTLGEGFASKNANH
QMKKLSSDEFKQMRDLLDLPIPDARFDDGQVPYGHPGADSAEVRYLQERRAALGGPAPAR
RVHPLAPLPAPADKAFAAFDKGSGTQSIATTMAFVRLVKDLVRDKETGKRWVPIVPDEAR
TFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAVNGQILNEGITEAGSMADFIAASTS
YATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGH
SPVIAATNPAALSYDPAFAYEIAAIVKEGLRRMYGEAAEGEDQNVFYYLTVYNEPMPQPA
KPGHAGVDEGILKGLYRFNTAESAGLELPANASRVQLLASGTAIHWALEAQKLLAAEWGV
AADVWSATSWTELRRDALEADAALLRGEERVPYVRQALEGVDSPVLAVSDYMRQVPDQIA
QWVEQDYTSLGADGFGISDTRVASRRHFGVDAQSIVVAALAQLARRGEVQATSVKEARER
YGL
NT seq
2712 nt
NT seq
+upstream
nt +downstream
nt
atgaccgatcccgtaggcaagattccgagcgagctcgaccagctcccggaccgtgacacc
gaggagaccgccgagtgggcggcctccctcgacgccgtcaccaaggccgccggccctcac
cgggccgcctacctgatgcgccgcacgctccagcacgccgagggcgcgggcctggccctg
cccaagctgctggagacggactacctcaacaccatccccacctccgccgagcccgtcatc
gacggtgacgaggagatggagcgccggatcaccgcctggaaccgctggaacgcggccgcg
atggtcacccgcggcgccaagcacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttcaagggcaaggacgccaaggacgct
cccgggtccggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgc
gccttcctcgacggccggctgtccgaggaccacctcgacaacttccgccaggaggccggc
ggcaacggcctgccctcctacccgcacccgcgccggctgccctggctgtgggagttcccc
accgtctccatgggcctcggcccgctctccgcgatctaccaggcgcgcttcaaccgctac
ctgaccaaccgctccatcaaggacgtctccgcctcccacgtgtgggccttcctcggcgac
ggcgagatggacgagcccgaggccacggcggcgctcgcgctggcggcccgcgagggtctg
gacaacctgaccttcgtcatcaactgcaacctgcagcgcctcgacggtccggtccgcgcc
aacttcaagatcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtc
aagaccctgtggggcaacgcctgggacgagctgttcgcgctcgacaccaccggcgccctg
gtccgccgcctccgcgaggtgccggacgcccaggtccagacgtaccagacccgcgacgcc
gcctacatccgccaggacttcttcggcaaggacccggcgctcgtcgcgatggcgcagctg
ctgagcgacgacaagatcctcgagtgcttccacctctcccgcggtggccacgagccgcgc
aaggtgtacgccgcgtacaaggccgccctggagttcaagggcgcgccgaccgtcatcctg
gcgcagaccgtcaagggcttcaccctcggtgagggcttcgcgtcgaagaacgcgaaccac
cagatgaagaagctctcgtcggacgagttcaagcagatgcgtgacctgctcgacctgccg
atcccggacgcgcggttcgacgacggccaggtgccctacggccacccgggcgccgactcc
gccgaggtccgctacctccaggagcgccgcgccgccctcggcggccccgccccggcccgc
cgcgtccacccgctcgcgccgctgccggccccggccgacaaggcgttcgccgccttcgac
aagggctccggcacgcagtccatcgccaccacgatggccttcgtgcgcctggtcaaggac
ctcgtccgggacaaggagaccggcaagcgctgggtcccgatcgtgcccgacgaggcccgc
accttcggcatggagtcgctgttcccgtcgctcggcatctactcgccgaagggccagacg
tacgagccggtcgaccgcgaccagctgatgtactacaaggaggccgtcaacggccagatc
ctgaacgagggcatcaccgaggccggctcgatggccgacttcatcgccgcctcgacgtcg
tacgcgacgcacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctgg
cagcggaccgccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtc
ggcgcgaccgccggccgcaccaccctgaccggtgagggcctgcagcacgccgacggccac
tccccggtgatcgcggccaccaacccggcggcgctctcctacgacccggcgttcgcctac
gagatcgcggccatcgtcaaggagggcctgcgccggatgtacggcgaggcggccgagggc
gaggaccagaacgtcttctactacctcaccgtctacaacgagccgatgccgcagccggcc
aagccgggccacgcgggcgtcgacgagggcatcctcaagggcctgtaccgcttcaacacg
gccgagtcggccggcctggagctgcccgcgaatgcctcgcgcgtccagctgctcgcctcc
ggcaccgcgatccactgggccctggaggcgcagaagctgctcgccgccgagtggggcgtg
gccgccgacgtgtggtccgcgacctcctggaccgagctgcgccgcgacgcgctggaggcc
gacgcggccctgctgcgcggcgaggagcgcgtcccgtacgtgcgccaggccctggaaggc
gtggactccccggtcctggccgtctcggactacatgcgccaggtcccggaccagatcgcg
cagtgggtcgagcaggactacacctcgctgggcgccgacggcttcggcatctcggacacc
cgcgtcgcgtcccgccgccacttcggcgtcgacgcccagtcgatcgtggtcgccgccctg
gcccagctcgcccgccgcggcgaggtccaggccacctcggtgaaggaggcccgcgagcgc
tacggcctgtag
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