Streptomyces laurentii: SLA_1992
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Entry
SLA_1992 CDS
T05205
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
slau
Streptomyces laurentii
Pathway
slau00010
Glycolysis / Gluconeogenesis
slau00020
Citrate cycle (TCA cycle)
slau00620
Pyruvate metabolism
slau00785
Lipoic acid metabolism
slau01100
Metabolic pathways
slau01110
Biosynthesis of secondary metabolites
slau01120
Microbial metabolism in diverse environments
slau01200
Carbon metabolism
slau01210
2-Oxocarboxylic acid metabolism
Module
slau_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
slau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SLA_1992
00020 Citrate cycle (TCA cycle)
SLA_1992
00620 Pyruvate metabolism
SLA_1992
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SLA_1992
Enzymes [BR:
slau01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SLA_1992
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
BAU82929
UniProt:
A0A160NW61
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Position
2101912..2104644
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AA seq
910 aa
AA seq
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MASASDRNPIIIGGLPSQVPDFDPEETREWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPYFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFLLDRLTETQLDGFRQ
EKSRFPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSRSHVW
AFLGDGEMDEPESLGQLTLAARENLDNLTFVVNCNLQRLDGPVRGNGKIIQELESVFRGA
GWNVIKLIWDRSWDPLLAQDRDGTLVNRMNTTPDGQYQTYATETGAYIRDHFFGDDQRLR
TMVENMTDDQILHLGRGGHDHRKIFAAFSAAKAHKGQPTVILAKTVKGWTLGPNFEGRNA
THQMKKLTVDDLKGFRDRLHIPITDQQLEEGLPPYYHPGRNSEEIQYMHDRRKALGGYVP
SRVVRAKPLELPDDKTYAAVKKGSGQQSIATTMAFVRLLKDLMRDKELGRRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRELLLSYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSHLLASTNPACVAYDPAFGFEIAHIVQDGLRRMYGPDSEDVFYYLTVYNEPIQHPAEPA
DVDVEGILKGIHLYRRGEAGAIPAQIMASGVGVPWALEAQRILAEEWNVRADVWSATSWN
ELRREAVAVEEHNLLHPEEEQRVPYVTRKLQAAQGPFVAVSDWMRSVPDQIARWVPGTYN
SLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAREGKVDRSALKQAIDRYQLLDASA
ADPGTAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcaacccgatcatcattggcggccttcccagccaggttccc
gacttcgacccggaagagacccgggaatggctcgactccctggacgccgccgtcgacgag
cgaggccgggagcgggcccgttatctcatgctgcggctgatcgagcgggcccgcgagaag
cgcgtcgccgtgccggagatgcgcagcacggactacgtcaacaccatcgcgaccaaggac
gagccgtacttccccggcaacgaggaaatcgagcgcaaggtcctcaacgccacccgctgg
aacgccgccgtcatggtctcgcgcgcccagcgcccgggcatcggcgtcggcggccacatc
gcgaccttcgcctcctccgcgtcgctctacgacgtcggtttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcccccggcatc
tacgcccgcgccttcctcctcgaccggctgaccgagacccagctcgacggcttccggcag
gagaagtcgcggttcccgaacggcctgtcgtcgtacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtgtcgatgggcctcggcccgctcggcgcgatctaccaggcc
cggatgaaccgctacatggaggcgcgcggcatcgccgacacctcccgctcgcacgtgtgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcggccagctgaccctcgcg
gcccgggagaacctcgacaacctcaccttcgtcgtcaactgcaacctccagcggctcgac
ggcccggtacgcggcaacggcaagatcatccaggagctggagtcggtcttccgcggcgcc
ggatggaacgtcatcaagctcatctgggaccgctcctgggacccgctgctcgcccaggac
cgcgacggcaccctcgtcaaccggatgaacaccaccccggacggccagtaccagacgtac
gccacggagaccggcgcgtacatccgcgaccacttcttcggcgacgaccagcggctgcgg
accatggtcgagaacatgaccgacgaccagatcctgcacctggggcgcggcggtcacgac
caccggaaaatcttcgcggcgttctcggcggccaaggcgcacaagggccagccgacggtg
atcctcgccaagaccgtcaagggctggacgctgggccccaacttcgagggccgcaacgcc
acccaccagatgaagaagctcacggtcgacgacctcaagggcttccgcgaccggctgcac
atccccatcacggaccagcagttggaggagggcctgccgccgtactaccacccgggccgg
aactccgaggagatccagtacatgcacgaccgccgcaaggcgctcggcgggtacgtgccc
tcccgcgtggtccgcgccaagccgctggaactgcccgacgacaagacgtacgcggcggtc
aagaagggctccgggcagcagtccatcgccaccacgatggccttcgtccggctgctcaag
gacctgatgcgggacaaggaactcggccggcgcttcgtgctgatcgcgccggacgagtac
cgcaccttcggcatggactcgttcttcccgagcgccaagatctacaacccgctcggccag
cagtacgaggccgtggaccgcgaactgctcctgtcgtacaaggagtccccgaccggccag
atgctgcacgacggcatctcggaggcgggctgcaccgcctcgctgatcgcggccggctcg
gcgtacgccacgcacggcgaaccgctcatcccggtctacgtcttctactcgatgttcggc
ttccagcgcaccggcgaccagttctggcagatggccgaccagctggcgcgcggcttcgtg
ctcggcgcgaccgccggccggaccacgctgaccggtgagggcctgcagcacgccgacggc
cactcccatctgctcgcctcgaccaacccggcctgtgtcgcctacgacccggccttcggc
ttcgagatcgcgcacatcgtccaggacggtctgcgccgcatgtacgggccggactcggag
gacgtcttctactacctgacggtctacaacgagccgatccagcacccggcggagccggcg
gacgtggatgtcgagggcatcctcaagggcatccacctctaccggcgcggcgaggccggg
gcgatccccgcgcagatcatggcgtcgggtgtcggcgtgccgtgggcgctggaggcgcag
cggatcctcgccgaggagtggaacgtccgcgccgacgtgtggtccgcgacctcctggaac
gagctgcgccgcgaggccgtggccgtcgaggagcacaacctgctgcacccggaggaggag
cagcgcgtcccgtacgtgacgcgcaagctccaggccgcgcaggggccgttcgtcgcggtc
tccgactggatgcgttcggtgccggaccagatcgcgcgctgggtgccgggcacctacaac
tcgctgggcgcggacggcttcggcttcgcggacacgcgaggcgcggcccgccgcttcttc
cacatcgacgcccagtcgatcgtgctcgcggtgctcaccgaactggcccgcgagggcaag
gtcgaccgctcggccctgaagcaggccatcgaccggtaccagctgctggacgcgtcggcg
gcggacccggggacggcgggcggcgacgcgtaa
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