Streptomyces lydicus 103: SL103_07045
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Entry
SL103_07045 CDS
T04699
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
slc
Streptomyces lydicus 103
Pathway
slc00010
Glycolysis / Gluconeogenesis
slc00020
Citrate cycle (TCA cycle)
slc00620
Pyruvate metabolism
slc00785
Lipoic acid metabolism
slc01100
Metabolic pathways
slc01110
Biosynthesis of secondary metabolites
slc01120
Microbial metabolism in diverse environments
slc01200
Carbon metabolism
slc01210
2-Oxocarboxylic acid metabolism
Module
slc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
slc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SL103_07045
00020 Citrate cycle (TCA cycle)
SL103_07045
00620 Pyruvate metabolism
SL103_07045
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SL103_07045
Enzymes [BR:
slc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SL103_07045
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AOP46030
UniProt:
A0A1D7VH22
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Position
complement(1653614..1656346)
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERARER
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGVYARAFLLDRLSEAQLDAFRQ
EKSKAPHGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIMQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGILVNKLNTTPDGQFQTYATETGAYIREHFFGDDQRLR
AMVENMTDDQILHLGRGGHDHKKIYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVQDLKGFRDRLHLPIPDKELEDGLPPYYHPGRDSEEIQYMHDRRKSLGGYVP
TRVVRAKPLALPDDKAYAGAKKGSGQQKIATTMAFVRVLKDLMRDKEIGKRFVPIAPDEY
RTFGMDAFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGITEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSRGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVAYDPAYGYEIAHIVKDGLRRMYGENSEDVFYYLTVYNEPILHPAEPA
DVDVEGILKGLHRVKPGEKGEHAAQILASGVAVPWAVEAQQILADEWNVKADVWSATSWN
ELRREAVDAEEHNLLHPEEEQRVPYVTQKLQGAEGPTVAVSDWMRSVPDQIARWVPGTYQ
SLGADGFGFADTRGAARRFFHIDTQSIVLSVLTELAKEGKVDRSLLKQAIDRYQLLDVAA
ADAGEAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgaaacccgatcatcattggcggccttcccagccaggtcccg
gacttcgatcccgaagagacccaggaatggctcgactcgctcgacgcggctgtcgacgag
cgaggccgggaacgtgcccgctatctcatgctgcggctgatcgagcgcgcccgggagagg
cgtgtggccgtgcccgagatgcgcagcacggactacgtcaacaccatcgcgaccaaggac
gagccgttcttccccggcaacgaggagatcgagcgcaaggtcctgaacgcgacccggtgg
aacgccgccgtcatggtgtcccgcgcccagcgtccgggcatcggggtcggcggccacatc
gccaccttcgcctcctcggcgtccctctacgacgtgggcttcaaccacttcttccggggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcgtcgcccggtgtc
tacgcccgcgcgttcctcctcgaccgactgagcgaggcgcagctcgacgccttccgccag
gagaagtcgaaggccccgcacggcctgtccagctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggtccgctcggcgcgatctaccaggcc
cggatgaaccgctacatggaggcgcgcggcatcgccgacacctccaagtcgcacgtgtgg
gcctacctcggcgacggcgagatggacgagccggagtcgctcggccagctgtccatcgcc
gcccgtgagggcctggacaacctgaccttcgtcgtcaactgcaacctgcagcgcctggac
ggcccggtccgcggcaacggcaagatcatgcaggagctggagtcgcagttccgcggcgcc
ggctggaacgtcatcaagctggtgtgggaccgcagctgggacccgctgctcgcgcaggac
cgcgacggcatcctggtcaacaagctgaacaccacccccgacggccagttccagacgtac
gcgaccgagaccggcgcgtacatccgtgagcacttcttcggtgacgaccagcgcctgcgg
gcgatggtcgagaacatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
cacaagaagatctacgcggcgtacgcggcggccaaggcccacaagggccagccgacggtg
atcctcgcgcagaccgtcaagggctggacgctcggtccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgaccgtccaggacctcaagggcttccgcgaccggctgcac
ctgccgatcccggacaaggagctggaggacggcctgccgccgtactaccacccgggccgc
gactccgaagagatccagtacatgcacgaccggcgcaagtcgctgggcggctatgtcccc
acccgcgtcgtgcgcgccaagccgctggcactgccggacgacaaggcgtacgcgggtgcc
aagaagggctcgggccagcagaagatcgccacgaccatggcgttcgtccgggtgctgaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgccgatcgcccccgacgagtac
cgcaccttcggtatggacgcgttcttcccgtcggccaagatctacaacccgctgggccag
cagtacgagtcggtcgaccgcgaactgctcctggcctacaaggagtcgccgaccggccag
atgctgcacgacggcatcaccgaggccggctgcaccgcctcgctgatcgcggcgggctcc
gcctacgccacgcacggcgagccgctgatcccggtctacgtcttctactcgatgttcggg
ttccagcgcaccggcgaccagttctggcagatggccgaccagctctcgcgcggcttcgtg
ctcggcgcgaccgccggccgtacgacgctgaccggtgagggcctgcagcacgccgacggc
cactcccagctgctggcctcgaccaacccggcctgtgtcgcctacgacccggcctacggc
tacgagatcgcgcacatcgtcaaggacggtctgcgccggatgtacggcgagaactccgag
gacgtcttctactacctcaccgtctacaacgagccgatcctgcaccccgcggagccggcc
gacgtcgacgtcgagggcatcctcaagggtctgcaccgcgtcaagcccggcgagaagggc
gagcacgccgcccagatcctcgcctcgggtgtcgccgtgccgtgggccgtcgaggcccag
cagatcctcgcggacgagtggaacgtcaaggcggacgtctggtcggcgacctcctggaac
gagctgcgccgggaggcggtggacgccgaggagcacaacctcctgcacccggaggaggag
cagcgcgtcccgtacgtgactcagaagctccagggcgccgagggcccgacggtcgcggtc
tcggactggatgcgttccgttccggaccagatcgcgcgctgggtgccgggcacctaccag
tcgctgggtgccgacggcttcggcttcgcggacacccgcggcgcggcccgtcgcttcttc
cacatcgacacgcagtccatcgtcctgagcgtgctcaccgagctcgccaaggagggcaag
gtcgaccggtccctgctgaagcaggcgatcgaccgctaccagctcctggacgtcgcggcc
gccgacgcgggtgaggccggcggcgacgcctga
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