Streptomyces lydicus 103: SL103_08365
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Entry
SL103_08365 CDS
T04699
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
slc
Streptomyces lydicus 103
Pathway
slc00010
Glycolysis / Gluconeogenesis
slc00020
Citrate cycle (TCA cycle)
slc00620
Pyruvate metabolism
slc00785
Lipoic acid metabolism
slc01100
Metabolic pathways
slc01110
Biosynthesis of secondary metabolites
slc01120
Microbial metabolism in diverse environments
slc01200
Carbon metabolism
slc01210
2-Oxocarboxylic acid metabolism
Module
slc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
slc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SL103_08365
00020 Citrate cycle (TCA cycle)
SL103_08365
00620 Pyruvate metabolism
SL103_08365
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SL103_08365
Enzymes [BR:
slc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SL103_08365
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AOP46247
UniProt:
A0A1D7VHP8
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Position
complement(1944357..1947056)
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AA seq
899 aa
AA seq
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MPDPVRLPYSQLDQLPDRDPEETAEWRESLDAVTKAAGPHRAAYLMRRALEHTARTEGTA
LPSLLETDYVNTIPTSAEPDFPGDEALEARITAWNRWNAAAMVTRGSKLGLGGHIATFAS
AAWLYETGFEHFFHGKEDQSSGGSGDQLYIQGHASPGIYARAFLEGRLTEDHLDHFRQEA
GGEGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLEHRGIKDTANSHVWAFLG
DGEMDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRPNFKIVQELEAQFRAAGWNV
VKALWGRAWDEVFALDTDGALIRRLGETPDAQFQTYATRDAAYLREHFFGANESLQAIAR
TLSDAKLLELFQTSRAGHEPRKVYAAYRAAVEHKGAPTVILAQTVKGFTLGTGFESRNAN
HQMKKLTMAEFRTMRDVLELPIPDSALEGDLVPYWRPAEDSPEMVYLRERRAALGGPAPA
RKVVPKPLPMPADKTFDALKKGSGSQEIATTMAFVRLVKDLMRDKETGRRWVPIVPDEAR
TFGMESLFPTAGLYSPKGATYDPVDRDQLLWYKEARDGQILNEGITEAGSLADFTAAATS
YATHGEPMIPFYIFYSMFGWQRTADQFWALADQLGRGFVIGATAGRTTMTGEGLQHADGH
SHLIASTNPAALSYDPAFAYEVAVIVKEGLRRMYGSTEAHPAGEDVFYYLTVYNETKVQP
AMPEGVEEGILKGLYRYQEAAPDAAADAPRLQLLASGTAVHWALEAQELLAADWGVAADV
WSAPSWTELRRDALECDAARLEGEDRIPYVTRALAGAPGPVVAVSDWMRAVPDQIAPWVE
QDWTSIGTDGFGLSDTREAARRHFGVDAQSVVVQSLAALARRGEVKPEAVKEAKERYGL
NT seq
2700 nt
NT seq
+upstream
nt +downstream
nt
atgcccgaccccgtgcgcctgccgtacagccagctcgaccagctcccggaccgcgacccc
gaggagaccgccgagtggcgcgagtcgcttgacgccgtcaccaaggcagcgggtccgcat
cgcgccgcctacctgatgcgccgtgccctggagcacaccgcgcgcaccgagggcaccgcc
ctgccgtccctgctggagacggactacgtcaacaccatcccgacctccgccgagcccgac
ttcccgggcgacgaggcgctggaggcccggatcaccgcctggaaccgctggaacgccgcc
gcgatggtcacccgcggctccaagctcggcctcggcggccacatcgccaccttcgcgtcc
gccgcctggctgtacgagaccggcttcgagcacttcttccacggcaaggaggaccagtcc
tccggcggctccggcgaccagctctacatccagggccacgcctctcccggcatctacgcc
cgtgccttcctcgaaggccgcctcaccgaggaccacctcgaccacttccgccaggaggcc
ggcggcgagggcctgccctcctacccgcacccgcggcggctgccctggctgtgggagttc
ccgaccgtctccatgggcctcggcccgctctccgcgatctaccaggcgcgcttcaaccgc
tacctggagcaccgcggcatcaaggacaccgccaactcccacgtctgggcgttcctgggc
gacggcgagatggacgagcccgagtcgaccgccgccctggcgctggcgggccgtgagggc
ctggacaacctcaccttcgtcatcaactgcaacctgcagcgcctggacggcccggtccgc
cccaacttcaagatcgtgcaggagctggaggcccagttccgcgccgccggctggaacgtc
gtcaaggcgctgtggggccgcgcctgggacgaggtcttcgcgctcgacacggacggcgcg
ctgatacgccgcctcggcgagacccccgacgcgcagttccagacgtacgccacccgcgac
gccgcctacctgcgcgagcacttcttcggcgcgaacgagtcgctgcaggccatcgcccgt
acgctctccgacgccaagctgctggagctgttccagacctcccgcgccggccacgagccg
cgcaaggtctacgccgcctaccgggccgccgtcgagcacaagggcgcgccgacggtcatc
ctggcgcagaccgtcaagggcttcaccctcggcacgggcttcgagtcccgcaacgccaac
caccagatgaagaagctcaccatggcggagttccgcaccatgcgtgacgtgctcgaactc
cccatcccggacagcgcgctggagggcgacctggtgccgtactggcgcccggccgaggac
tcccccgagatggtctacctgcgcgagcggcgcgccgccctcggcggcccggcgcccgcc
cgcaaggtcgtccccaagccgctgccgatgccggccgacaagaccttcgacgcgctgaag
aagggctccggcagccaggagatcgccaccaccatggcgttcgtacggctggtcaaggac
ctgatgcgggacaaggagaccggcaggcgctgggtgccgatcgtccccgacgaggcccgc
accttcggcatggagtcgctcttcccgacggccggtctctactcccccaagggcgcgacg
tacgaccccgtcgaccgcgaccagctcctttggtacaaggaggccagggacggccagatc
ctcaacgagggcatcaccgaggccggttcgctcgccgacttcaccgccgccgcgacgtcg
tacgcgacgcacggcgagccgatgatccccttctacatcttctactcgatgttcggctgg
cagcgcaccgccgaccagttctgggcgctggccgaccagttgggccgcggcttcgtgatc
ggcgccaccgcgggccgtacgacgatgaccggcgagggcctgcagcacgccgacgggcac
tcgcacctgatcgcgtcgaccaaccccgcggcactctcctacgacccggccttcgcctac
gaggtggcggtcatcgtcaaggagggcctgcgccggatgtacggctcgaccgaggcccac
ccggccggcgaggacgtcttctactacctcacggtctacaacgagaccaaggtccagccc
gccatgccggaaggcgtcgaggagggcatcctcaagggcctctaccgctaccaggaggcg
gctcccgacgcggccgccgacgccccgcgcctgcagctgctggcttcgggcacggccgtc
cactgggccctggaggcgcaggaactgctggccgccgactggggcgtggcggcggacgtc
tggtcggcgccgtcctggacggagctgcgccgggacgccctggagtgcgacgccgcccgt
ctggagggcgaggaccggatcccgtacgtcacccgtgccctggctggcgcccccggtccg
gtcgtcgcggtcagcgactggatgcgggccgttccggaccagatcgccccctgggtcgag
caggactggacctccatcgggaccgacggcttcggcctgtccgacacccgcgaggcagcc
cgccgccacttcggtgtggacgcccagtccgtcgtcgtccagtccctggccgccctggcc
cgccgcggcgaggtcaagccggaggcggtcaaggaggcgaaggagcgctacgggctgtga
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