KEGG   PATHWAY: sle00740
Entry
sle00740                    Pathway                                
Name
Riboflavin metabolism - Streptomyces leeuwenhoekii
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
sle00740  Riboflavin metabolism
sle00740

Other DBs
GO: 0006771
Organism
Streptomyces leeuwenhoekii [GN:sle]
Gene
sle_56540  sle_56540; Riboflavin biosynthesis protein ribBA [KO:K14652] [EC:4.1.99.12 3.5.4.25]
sle_57740  sle_57740; HAD-Superfamily Hydrolase [KO:K20862] [EC:3.1.3.102 3.1.3.104]
sle_56550  sle_56550; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
sle_56520  sle_56520; Riboflavin synthase alpha chain [KO:K00793] [EC:2.5.1.9]
sle_19710  sle_19710; Riboflavin biosynthesis protein ribF [KO:K11753] [EC:2.7.1.26 2.7.7.2]
sle_61090  sle_61090; NADPH-Dependent FMN Reductase [KO:K00299] [EC:1.5.1.38]
sle_08450  sle_08450; FMN reductase [KO:K00299] [EC:1.5.1.38]
sle_31290  sle_31290; FMN reductase [KO:K00299] [EC:1.5.1.38]
sle_07750  sle_07750; FMN reductase [KO:K00299] [EC:1.5.1.38]
sle_31090  sle_31090; Probable aromatic acid decarboxylase [KO:K03186] [EC:2.5.1.129]
sle_04270  sle_04270; Probable aromatic acid decarboxylase [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
PMID:12136096
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
PMID:11856310
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
PMID:12867427
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
PMID:16042598
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
sle00030  Pentose phosphate pathway
sle00040  Pentose and glucuronate interconversions
sle00230  Purine metabolism
sle00860  Porphyrin metabolism
sle00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

DBGET integrated database retrieval system