Streptomyces leeuwenhoekii: sle_49570
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Entry
sle_49570 CDS
T04414
Symbol
sle_49570
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00010
Glycolysis / Gluconeogenesis
sle00020
Citrate cycle (TCA cycle)
sle00620
Pyruvate metabolism
sle00785
Lipoic acid metabolism
sle01100
Metabolic pathways
sle01110
Biosynthesis of secondary metabolites
sle01120
Microbial metabolism in diverse environments
sle01200
Carbon metabolism
sle01210
2-Oxocarboxylic acid metabolism
Module
sle_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
sle_49570 (sle_49570)
00020 Citrate cycle (TCA cycle)
sle_49570 (sle_49570)
00620 Pyruvate metabolism
sle_49570 (sle_49570)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
sle_49570 (sle_49570)
Enzymes [BR:
sle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
sle_49570 (sle_49570)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
CQR64415
UniProt:
A0A0F7VXB9
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Position
chromosome:complement(5824684..5827386)
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AA seq
900 aa
AA seq
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MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVAQAAGPHRAAYLMRRTLERAEGAGIAL
PKLLETDYVNTIPTAAEPAVDGDEEMEARITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFRGKEADGSGDQLFIQGHASPGIYARAFLDGRLGEDHLDNFRRETGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTARGIKDTSASHVWAFLGDGEM
DEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTL
WGSAWDELFQLDTTGALVRRLREVPDAQIQTYQTRDAAYIREDFFGKDPALAEMAKLLSD
DKILECFHVSRGGHEPRKVYAAYRAALAHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLTVDEFKAMRDRLNLPIKDSDFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PVPALPAPAEKAFAAFDKGSGSQNVATTMAFVRLIKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTSYAT
HGEPMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLIGATAGRTTLTGEGLQHADGHTPV
IAATNPASLTYDPAFAYEVAVIVREGLRRMYGEAKEGEDQNVFYYLTVYNEPLPQPAKPA
GLGIDEGIVKGLYRFNTAESAGLTPAAGAPRIQLLGSGTAIHWALKAQKMLTEEWGVAAD
VWSATSWTELRRDAMEADAALLRGEERVPYVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTREAARRHFGVDAESIVVAALAQLAKRGEVKATAVKEARERYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagcccagcgagctggaccagctcccggaccgcgacccc
gaggagaccgccgagtggcaggcctccctggacgccgtcgcccaggcggccgggccgcac
cgtgccgcgtacctgatgcgccgcacgctggagcgcgccgagggcgccggcatcgccctg
ccgaagctcctggagaccgactacgtcaacaccatccccaccgccgccgagcccgccgtg
gacggtgacgaggagatggaggcgcggatcaccgcgtggaaccgctggaacgcggcggcc
atggtgacccggggcagcaagtacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttccggggcaaggaggccgacggctcg
ggcgaccagctcttcatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggctcggcgaggaccacctcgacaacttccgccgcgagaccggcggcaacggc
ctgccgtcctacccgcacccgcggcgcctgccgtggctgtgggagttccccaccgtctcc
atgggcctcggcccgctttccgcgatctaccaggcgcggttcaaccgctacctgaccgcg
cgcggcatcaaggacacctccgcctcgcacgtgtgggcgttcctcggcgacggcgagatg
gacgagcccgagtcgacggcggcgctcgcgctcgcctcccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctccagcgcctggacggcccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtggtcaagacgctg
tggggctcggcctgggacgagctgttccagctcgacaccaccggcgcgctggtacgccgc
ctgcgcgaggtaccggacgcgcagatccagacgtaccagacccgcgacgccgcctacatc
cgtgaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctgagcgac
gacaagatcctcgagtgcttccacgtctcccgtggcggtcacgagccgcgcaaggtctac
gccgcgtaccgggcggcgctcgcccacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggtgagggcttcgcctccaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaaggcgatgcgcgaccgcctgaacctgccgatcaaggac
agcgacttcgtcgacggcgtggtcccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgccgccctcggcggtccggccccggcccgccgcgtgcac
ccggtcccggcgctgcccgccccggccgagaaggcgttcgccgccttcgacaagggctcc
ggctcgcagaacgtcgcgaccacgatggcgttcgtccgcctgatcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagtcgctcttcccgtcgctgggcatctactcgcccaagggccagacgtacgagccg
gtcgaccgcgaccagctcatgtactacaaggaagccaagaacggccagatcctcaacgag
gggatcaccgaggccggctcgatggccgacttcatcgccgcctccacgtcgtacgcgacg
cacggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctgatcggcgccacc
gccggccgcaccaccctgaccggtgagggcctgcagcacgccgacggccacaccccggtg
atcgcggcgaccaaccccgcgtcgctgacgtacgacccggcgttcgcctacgaggtcgcc
gtcatcgtccgcgagggtctgcgccggatgtacggcgaggccaaggagggcgaggaccag
aacgtcttctactacctgacggtctacaacgagccgctgccgcagcccgccaagccggcc
ggcctcggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcc
gcgggcctgaccccggcggcgggtgccccgcgcatccagctcctgggctcgggcacggcg
atccactgggcgctcaaggcgcagaagatgctcaccgaggagtggggcgtggccgccgac
gtgtggtccgcgacctcctggaccgagctgcgccgcgacgcgatggaggccgacgccgcc
ctgctgcgcggcgaggagcgggtgccgtacgtccgccaggcgctccagggcgccgagggc
ccggtgctggccgtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtg
gagcaggactggtcctcgctgggcgccgacggcttcggtctgtcggacacccgtgaggcg
gcccgccgccacttcggcgtcgacgccgagtcgatcgtggtcgcggccctggcccagctc
gccaagcgcggcgaggtcaaggcgacggccgtgaaggaggcgcgcgagcgctacggcctg
tag
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