Streptomyces leeuwenhoekii: sle_52760
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Entry
sle_52760 CDS
T04414
Symbol
sle_52760
Name
(GenBank) Cobalt-precorrin-3B C(17)-methyltransferase
KO
K13541
cobalt-precorrin 5A hydrolase / cobalt-factor III methyltransferase / precorrin-3B C17-methyltransferase [EC:
3.7.1.12
2.1.1.272
2.1.1.131
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00860
Porphyrin metabolism
sle01100
Metabolic pathways
sle01240
Biosynthesis of cofactors
Module
sle_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
sle_52760 (sle_52760)
Enzymes [BR:
sle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.131 precorrin-3B C17-methyltransferase
sle_52760 (sle_52760)
2.1.1.272 cobalt-factor III methyltransferase
sle_52760 (sle_52760)
3. Hydrolases
3.7 Acting on carbon-carbon bonds
3.7.1 In ketonic substances
3.7.1.12 cobalt-precorrin 5A hydrolase
sle_52760 (sle_52760)
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Motif
Pfam:
TP_methylase
CbiG_N
CbiG_C
Motif
Other DBs
NCBI-ProteinID:
CQR64734
UniProt:
A0A0F7VW48
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Position
chromosome:complement(6189769..6191460)
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AA seq
563 aa
AA seq
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MIGLISATSAGAAARDRLAAAWPDRTRVYDGPVKDAVRRAFAECEQLVCFLATGAVVRLV
APLLEEKTTDPGVVCVDEAGRFAVSLVGGHGGGANDLARAVGEVLGAEPVVTTATDATGV
AGLDTLGLPVEGAVAAVSRALLDGEPVALRAEVAWPLPPLPVAGDGPYTIRVTDRLVEPA
EREAVLRPPTLVVGVGASKGAPVTEVLEVIDGALRDAGLSVRSVAELATVDAKAGEPGIV
EAAARLGVPLVTYAAGDLARVEVPNPSDAPLAAVGTPSVAEAAALVRGGELLVPKRKSAA
SPAMATCAVVRRPGRGRLAVVGLGPGARDLLTPRAKAELERASVLVGLDQYVDQIRDLLR
PGTRILESGLGAEEERARTAVAEARKGHAVALIGSGDAGVYAMASPALAEASDDIDVVGV
PGVTAALAAGAILGAPLGHDHVSISLSDLHTPWEVIERRVRAAAEADLVVTFYNPRSRGR
DWQLPKALAILAGHREPGTPVGVVRNASRPDESSRVTTLAALDPATVDMMTVVTVGNTAT
RLIAGRMVTPRGYRWQENQEEPE
NT seq
1692 nt
NT seq
+upstream
nt +downstream
nt
gtgatcggcctcatttccgccacctcggcgggagcggcggcgcgggaccggctggccgcg
gcgtggccggaccgcacgcgcgtgtacgacggcccggtgaaggacgccgtgcggcgggcg
ttcgccgagtgcgagcaactggtgtgcttcctggcgacgggggcggtcgtccggctggtc
gcgccgctgctggaggagaagacgaccgatccgggcgtggtctgcgtcgacgaggccggg
cggttcgcggtgtcgctggtcggcgggcacggcggcggcgccaacgacctcgcccgcgcg
gtcggcgaggtgctgggtgccgagccggtggtgacgacggcgacggacgccaccggtgtc
gcgggactggacacgctcgggctgcccgtggagggcgcggtcgccgcggtgtcgcgggcc
ctgctggacggcgaaccggtggcgctgcgggccgaggtggcctggccgctgccgccgctg
ccggtcgccggcgacgggccgtacacgatccgggtgacggaccgtctcgtcgagcccgcc
gagcgggaggccgtgctgcgcccgccgacgctggtggtcggggtcggcgcgtccaagggg
gcgcccgtgaccgaggtgctcgaggtgatcgacggtgccctgcgggacgcggggctgtcc
gtgcgcagcgtcgccgagctggccaccgtggacgccaaggccggggagcccggcatcgtc
gaggccgccgcccggctgggggtgccgctggtgacgtacgccgccggggacctggcccgc
gtggaggtgcccaacccctccgacgcgccgctcgccgcggtgggcacgccctcggtcgcg
gaggcggcggcgctggtgcgcggcggcgaactcctcgtgcccaagcggaagtcggcggcc
agccccgccatggcgacctgcgcggtcgtacggcggcccggacgcggccggctcgcggtg
gtcgggctcgggccgggcgcccgcgacctgctcaccccgcgcgccaaggccgaactggag
cgggcgtcggtgctggtcggcctcgaccagtacgtcgaccagatccgcgacctgctgcgg
cccggcacccggatcctggagtcggggctcggcgcggaggaggaacgggcgcggacggcg
gtggccgaggcccgcaaggggcacgccgtcgcgctgatcggcagcggcgacgccggggtg
tacgccatggcctcccccgcgctcgccgaggcgtccgacgacatcgacgtggtcggcgtc
ccgggggtcacggcggcgctcgcggccggggcgatcctgggggcgccgctgggccacgac
catgtgtcgatcagcctgtccgacctgcacaccccgtgggaggtcatcgagcggcgggtg
cgggcggcggccgaggccgatctcgtcgtgaccttctacaacccgcgcagccggggccgc
gactggcagctccccaaggcgctcgcgatcctcgccgggcaccgggagccggggacaccg
gtcggtgtcgtccgcaacgcctcccggcccgacgagtccagccgggtgacgacgctcgcc
gcgctcgatccggccacggtcgacatgatgacggtcgtgacggtgggcaacaccgcgacc
cgcctgatcgcgggacgcatggtgaccccgcgcggctaccgctggcaggagaaccaggag
gaaccggagtga
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