Streptomyces liliifuscus: JEQ17_37140
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Entry
JEQ17_37140 CDS
T08169
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
slf
Streptomyces liliifuscus
Pathway
slf00270
Cysteine and methionine metabolism
slf00450
Selenocompound metabolism
slf00670
One carbon pool by folate
slf01100
Metabolic pathways
slf01110
Biosynthesis of secondary metabolites
slf01230
Biosynthesis of amino acids
slf04980
Cobalamin transport and metabolism
slf04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
slf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
JEQ17_37140 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
JEQ17_37140 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
JEQ17_37140 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
JEQ17_37140 (metH)
04980 Cobalamin transport and metabolism
JEQ17_37140 (metH)
Enzymes [BR:
slf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
JEQ17_37140 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
QQM44483
UniProt:
A0A7T7L124
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All DBs
Position
8612422..8615949
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AA seq
1175 aa
AA seq
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MASSPNPSLSSSSAYSRTRTDALREALATRVVVADGAMGTMLQAQDPTMEDFENLEGCNE
ILNLTRPDIVRSVHEEYFAVGVDCVETNTFGANHAALAEYDIAERVFELSESGARIAREV
ADEFTASTGQQRWVLGSMGPGTKLPTLGHAPYTLLRDAYQRNAEGMIAGGADALLVETTQ
DLLQTKASVIGARKALDTLGVDLPLIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGL
NCATGPAEMSEHLRYLARHSRIPLSCMPNAGLPVLGKNGAHYPLTAPELADAQETFVREY
GLSLIGGCCGTTPEHLRQVVERVRDLTPTARDPRPEPGAASLYQTVPFRQDTAYMAIGER
TNANGSKKFREAMLDGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAGRFAT
ASTLPIVLDSTEVPVIRAGLEKLGGRAVINSVNYEDGDGPESRFAKVTGLAQEHGAALIA
LTIDEEGQARTVEHKVAIAERLIEDLTENWGIHESDILIDTLTFTICTGQEESRKDGIST
IEAIRELKRRRPDVQTTLGLSNISFGLNPAARVLLNSVFLDECVKAGLDSAIVHASKILP
IARFDDEQVSTALDLIYDRRAEGYDPLQKLMALFEGATTKSLKAGRAEELAALPLDERLK
RRIIDGEKNGLEADLDEALQTRPALDIVNETLLDGMKVVGELFGSGQMQLPFVLQSAEVM
KTAVAHLEPHMEKTDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVS
AILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRKMAADYPVILGGAALTRAYVEQD
LHEIYEGEVRYARDAFEGLRLMDALIAVKRGVPGASLPELKQRRVRATPQTVVEERPEEG
SVRSDVSIDNPVPEPPFWGTRVIKGIQLKEYSSWLDEGALFKGQWGLKQARKGDGPTYEE
LVETEGRPRLRGLLDQLQTGNLLEAAVVYGYFPCVSKDDDLILLDEQGNERTRFTFPRQR
RGRRLCLADFFRPEESGETDVVGLQVVTVGSRIGEETAKLFEANAYRDYLELHGLSVQLA
EALAEYWHARVRSELGFAGEDPADVEDMFALKYRGARFSLGYGACPDLEDRAKIARLLEP
ERIGVHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3528 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgtcgcctaacccgtccctctcgtcctcctccgcctacagcaggacccgaacc
gatgccctccgcgaggcgctcgccacccgcgtggtggtggccgacggtgcgatgggcacg
atgctgcaggcacaggatccgacgatggaggacttcgagaatctcgaaggctgcaacgag
atcctgaacctcacgcgcccggacatcgtccgatccgtccacgaggagtacttcgccgtc
ggcgtcgactgcgtggagaccaacaccttcggcgccaaccacgcggccctcgccgagtac
gacatcgccgagcgcgtcttcgagctctccgagtcgggtgcccgcatcgcccgcgaggtc
gccgacgagttcaccgcctcgaccgggcagcagcgctgggtgctcggctccatgggcccc
ggcaccaagctgccgaccctcggccacgccccgtacaccctgctgcgcgacgcctaccag
cggaacgcggagggcatgatcgccggcggcgccgacgcgctgctcgtggagaccacccag
gacctgctgcagaccaaggcgtcggtcatcggcgcccgcaaggccctggacaccctcggc
gtcgacctgccgctgatcgtctcggtgaccgtcgagaccaccggcaccatgctgctcggc
tcggagatcggcgccgcgctcaccgcgctggagccgctcggcatcgacatgatcggcctg
aactgcgccacgggccccgccgagatgagcgagcacctgcgctatctggcccgccactcc
cgcatcccgctgtcctgcatgccgaacgcgggcctccccgtcctcggcaagaacggcgcc
cactacccgctcacggcacccgagctggccgacgcccaggagaccttcgtacgcgagtac
ggcctctccctgatcggcggctgctgcggcacgacccccgagcacctgcgccaggtcgtc
gagcgcgtccgggacctgacgccgaccgcgcgcgacccgcgccccgagcccggcgccgcc
tcgctctaccagaccgtgccgttccgccaggacaccgcgtacatggcgatcggcgagcgg
acgaacgccaacggctcgaagaagttccgcgaggccatgctggacggccgctgggacgac
tgtgtggagatggcccgcgaccagatccgcgagggcgcgcacatgctcgacctgtgcgtc
gactacgtgggccgcgacggcgtcgccgacatggaggagctggccggccgcttcgccacc
gcctccaccctgccgatcgtgctcgactccaccgaggtccccgtcatccgggccggcctg
gagaagctcggcggccgcgcggtcatcaactccgtcaactacgaggacggcgacggcccc
gagtcgcgcttcgcgaaggtcaccgggctcgcgcaggagcacggcgccgcgctgatcgcg
ctgaccatcgacgaggagggccaggcccgcaccgtcgagcacaaggtcgccatcgccgag
cgcctgatcgaggacctgacggagaactggggcatccacgagtcggacatcctcatcgac
accctgaccttcacgatctgcaccggtcaggaggagtcccgcaaggacggcatctcgacg
atcgaggcgatccgcgaactcaagcgccgccgcccggacgtacagaccaccctcggtctg
tccaacatctccttcggcctcaacccggccgcccgtgtcctgctcaactcggtcttcctc
gacgagtgcgtcaaggcgggcctcgactcggcgatcgtgcacgcgtcgaagatcctgccg
atcgcccgcttcgacgacgagcaggtcagcacggccctcgacctgatctacgaccgtcgc
gccgagggttacgaccccctccagaagctgatggcgctgttcgagggcgccaccaccaag
tccctgaaggcgggccgggccgaggaactggccgcgctgcccctggacgagcggctcaag
cggcgcatcatcgacggcgagaagaacggactggaagccgatctcgacgaggcactccag
acccgccccgccctcgacatcgtcaacgagacgctcctcgacggcatgaaggtcgtcggt
gagctgttcggttccggccagatgcagctgccgttcgtgctccagtcggccgaggtcatg
aagaccgccgtggcccatctcgaaccgcacatggagaagaccgacgacgagggcaagggc
accatcgtgctggccaccgtccgcggcgatgtccacgacatcggcaagaacctcgtcgac
atcatcctgtccaacaacggctacaacgtcgtcaacctcggcatcaagcagcccgtctcc
gcgatcctggaggccgccgaggagcaccgcgccgacgtcatcggcatgtcgggcctgctg
gtcaagtccacggtgatcatgaaggagaacctggaggagctcaaccagcgcaagatggca
gccgactaccccgtgatcctcggcggcgcggccctcaccagggcgtacgtcgagcaggac
ctgcacgagatctacgagggcgaagtccgctacgcccgggacgcgttcgagggcctgcgc
ctgatggacgcgctgatcgcggtcaagcgcggtgtgcccggcgcgagcctgcccgagctg
aagcagcgccgggtcagggccaccccccagacggtcgtcgaggagcgccccgaggagggc
tcggtccgctccgacgtgtccatcgacaacccggttcccgagccgccgttctggggcacc
cgcgtcatcaagggcatccagctcaaggagtactcctcctggctcgacgagggcgcgctc
ttcaagggccagtggggcctcaagcaggcgcgcaagggcgacgggccgacgtacgaggag
ctggtggagaccgagggccggccgcggctgcgcggtctcctcgaccagctgcagacgggg
aacctgctggaggcggccgtcgtctacggctacttcccgtgcgtgtccaaggacgacgac
ctgatcctcctggacgagcagggcaacgagcgcacccgcttcaccttcccgcgccagcgc
cgtggccgccggctctgcctggccgacttcttccggcctgaggagtccggcgagacggac
gtcgtcggcctccaggtcgtcaccgtcggctcccgcatcggcgaggagactgccaagctc
ttcgaggcgaacgcctaccgcgactacctcgaactgcacggtctgtccgtgcagttggcc
gaggccctcgccgagtactggcacgcgcgcgtgcgttccgaactcggcttcgcgggggag
gacccggccgacgtcgaggacatgttcgcgctcaagtaccgcggcgcccgcttctccctc
ggctacggcgcctgccccgatctggaggaccgcgccaagatcgcccgcctcctggagccc
gagcggatcggcgtccacctctccgaggagttccagctccacccggaacagtccacggac
gcgatcgtgatccaccacccggaggcgaagtacttcaacgccaggtaa
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