Streptomyces lunaelactis: SLUN_10705
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Entry
SLUN_10705 CDS
T06347
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
slk
Streptomyces lunaelactis
Pathway
slk00010
Glycolysis / Gluconeogenesis
slk00020
Citrate cycle (TCA cycle)
slk00620
Pyruvate metabolism
slk00785
Lipoic acid metabolism
slk01100
Metabolic pathways
slk01110
Biosynthesis of secondary metabolites
slk01120
Microbial metabolism in diverse environments
slk01200
Carbon metabolism
slk01210
2-Oxocarboxylic acid metabolism
Module
slk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
slk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SLUN_10705 (aceE)
00020 Citrate cycle (TCA cycle)
SLUN_10705 (aceE)
00620 Pyruvate metabolism
SLUN_10705 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SLUN_10705 (aceE)
Enzymes [BR:
slk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SLUN_10705 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AVZ72594
UniProt:
A0A2R4T0H3
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Position
2382106..2384775
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AA seq
889 aa
AA seq
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MTDPVGKLPSELDQLPDRDAEETAEWAASLDAVTEHAGPHRAAYLMRRTLQHAERAGVPV
PRLLETDYVNTIPTSAEPAFDGDEAMEARITAWNRWNAAAMVTRGSRFGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLSEQQLDHFRQEAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLHNRSIKDTANSHVWAFLGDGEM
DEPESTAALALAAREQLDNLTFVINCNLQRLDGPVRANFRVVQELEAQFRGAGWNVVKTL
WGSAWDELFQLDTTGALVRRLREVPDAQFQTYATRDVAYIREHFFGTGPALAQLASVLSD
AKIAECFYTSRGGHEARKVYAAYRAAVEHKGAPTVILAQTVKGYTLGKGFESKNANHQMK
KLTSDEFKGMRDLLGLPIPDSAFADGLVPYGHPGADSAEVRYLQERRAALGGPAPARRVQ
AVALPAPEERAFKALEKGSGKQEMATTMAFVRLVKDLMRDKETGRRWVPIVPDEARTFGM
ESLFPSAGIYSPLGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGAMADFIAASTSYATH
GEPMIPFYIFYSMFGWQRTADQMWQLADQLGRGFIVGATAGRTTLTGEGLQHADGHSHLI
ASTNPASLNYDPAFAYEIAVIVKDGLRRMYGPEAENVFYYLTVYNEPKRQPAMPEGVEEG
ILRGLYRFKEGVAASAEAPRLQLLASGTAIHWALEAQELLGSDWGVTADVWSATSWGELR
RDALEADEALLRGEQRTPYVTQALEGAPGPVLAVSDWMRQVPDQISQWVEQDYSSLGTDG
FGLSDTREAARRHFGVDARSIAVAALAQLVKRGEVPASAVKEARERYGF
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccgtaggcaagcttccgagcgagctcgaccagctcccggaccgtgacgcc
gaggagaccgccgagtgggcggcctccctcgacgccgtcaccgagcacgccggcccgcac
cgagccgcgtacctgatgcgccgcaccctccagcacgccgagagggccggcgttcccgtg
ccccggctgctggagacggactacgtcaacaccatccccacctccgccgagcccgccttc
gacggcgacgaggcgatggaagcccgcatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacgcgcggctcccgcttcggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttccgcggcaaggagggcgacggcagc
ggcgaccagctctacatccagggccatgcgtcccccggcatctacgcccgcgccttcctc
gacggacgtctgtccgagcagcagctcgaccacttccgccaggaggccggaggcaacggc
ctgccgtcctacccgcacccgcgccggctgccctggctctgggagttccccaccgtctcg
atgggcctcggcccgctctcggcgatctaccaggcgcgcttcaaccgctatctgcacaat
cgctccatcaaggacaccgccaactcgcacgtctgggccttcctcggcgacggcgagatg
gacgagcccgagtcgaccgcggccctcgccctcgcggcccgtgagcagctcgacaacctg
accttcgtcatcaactgcaatctgcagcgcctcgacggtccggtccgcgccaacttccgt
gtggtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtcaaaacgctg
tggggctccgcctgggacgagctgttccagctcgacaccacgggcgcgctggtccgccgg
ctgcgcgaggtcccggacgcccagttccagacgtacgcgacgcgtgatgtggcgtacatc
cgcgaacacttcttcggcaccgggcccgcgctcgcgcagcttgcctcggtcctgagcgac
gcgaagatcgccgagtgcttctacacctcccgcggcggccacgaggcccgcaaggtgtac
gcggcctaccgcgcggccgtcgagcacaagggcgcgccgaccgtgatcctcgctcagacg
gtgaagggctacacgctcggcaagggcttcgagtccaagaacgccaaccaccagatgaag
aagctgaccagcgacgagttcaagggcatgcgtgacctgctcggactcccgatcccggac
agcgcgttcgcggatggcctggtgccctacggccaccccggcgccgactccgccgaggtc
cgctacctccaggagcgccgcgccgcgctcggcggcccggccccggcccgccgcgtacag
gcggtggcgctgcccgcgcctgaggagcgtgccttcaaggcgctcgaaaagggctccggc
aagcaggagatggccaccaccatggccttcgtgcgcctggtcaaggacctgatgcgggac
aaggagaccggcaggcgctgggttccgatcgtcccggacgaggcccgcaccttcggcatg
gagtcgctcttcccgtcggccgggatctactccccgctggggcagacgtacgagccggtc
gaccgcgaccagctgatgtactacaaggaggccaaggacggccagatcctcaacgagggg
atcaccgaggccggtgccatggcggacttcatcgccgcgtcgacgtcgtacgcgacgcac
ggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacggcc
gaccagatgtggcagctcgccgaccagctcggcaggggcttcatcgtcggtgccaccgcc
ggtcgtacgaccctgaccggtgagggcctgcagcacgcggacggccactcgcatctgatc
gcctccacgaacccggcgtcgctcaactacgacccggcgttcgcgtacgagatcgccgtc
atcgtcaaggacggtctgcgccggatgtacggcccggaagcggagaacgtcttctactac
ctgacggtctacaacgagccgaagcggcagcccgcgatgcccgagggcgtcgaggaaggc
atcctccgcggtctctaccgcttcaaggagggagtcgccgcctcggcggaggctccccgc
ctccagctcctcgcctccggcacggcgatccactgggccctcgaggcgcaggaactgctc
ggctccgactggggagttacggccgacgtctggtccgcgacctcctggggcgagctgcgc
cgggacgcactggaggccgacgaggcactgctgcgcggcgaacagcgtacgccgtacgtc
acccaggcgctggagggcgctccgggcccggtgctggcggtgtccgactggatgcgccag
gtgccggaccagatcagccagtgggtcgagcaggactactcctcgctcggcacggacggc
ttcggtctctccgacacgcgtgaggcggcccgtcgccacttcggcgtggacgcccggtcg
atcgcggtcgccgcgctggcccagctggtcaagcgcggcgaggtcccggcctcggccgtg
aaggaggcgcgcgagcgctacgggttctga
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