Streptomyces lincolnensis: SLINC_2518
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Entry
SLINC_2518 CDS
T04801
Name
(GenBank) 2-oxoacid dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sls
Streptomyces lincolnensis
Pathway
sls00010
Glycolysis / Gluconeogenesis
sls00020
Citrate cycle (TCA cycle)
sls00620
Pyruvate metabolism
sls00785
Lipoic acid metabolism
sls01100
Metabolic pathways
sls01110
Biosynthesis of secondary metabolites
sls01120
Microbial metabolism in diverse environments
sls01200
Carbon metabolism
sls01210
2-Oxocarboxylic acid metabolism
Module
sls_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sls00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SLINC_2518
00020 Citrate cycle (TCA cycle)
SLINC_2518
00620 Pyruvate metabolism
SLINC_2518
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SLINC_2518
Enzymes [BR:
sls01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SLINC_2518
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
ANS64742
UniProt:
A0A1B1M8L5
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Position
2989789..2992494
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AA seq
901 aa
AA seq
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MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVAKAAGPHRAAYLMRRTLERAEGNGIAL
PKLLETDYVNTIPTAAEPSAPGDEEMERKITAWNRWNAAAMVTRGSKHGVGGHIATFASA
AWLYETGFNHFFKGKEADGSGDQLYIQGHASPGIYARAFLDGRLSEDHLDNFRRESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTHRGIKDVSASHVWAFLGDGEM
DEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSL
WGSAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGKDPALAEMAKLLSD
DKILECFHLSRGGHEARKVYAAYRAAVEFKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLTVDEFKSMRDLLELPIPDAQFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPAPAEKAFAAFDKGSGTQNVATTMAFVRLIKDLVRDKDSGRRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTSYAT
HGETMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAAIVKDGLRRMYGEAAPGEDQNVFYYLTVYNEPLPQPAKPA
GTAVDEGIVKGLYRFNTAESAGVDVAAANAPRVQLLGSGTAIHWALKAQRLLAEEWGVAA
DVWSATSWSELRRDALEADAALLRGEERVPYVRQALQGAEGPVLAVSDYMRQVPDQIAQW
VEQDYSSLGADGFGLSDTREAARRHFGVDAESVVVAALAQLARRGEVKATAVKEARAKYG
L
NT seq
2706 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgagctcgaccagctccccgaccgggacccc
gaggagaccgccgaatggcaggcctcgctggacgcggtcgccaaggcggccggcccgcac
cgtgccgcgtacctgatgcgccgcacactggagagggcggagggcaacggcatcgcgctg
ccgaagctcctcgagaccgactacgtcaacaccatccccaccgccgccgagccgtccgcg
cccggtgacgaggagatggagcggaagatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccgcggctccaaacacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttcaagggcaaggaggccgacggctcg
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggctcagcgaggaccacctcgacaacttccgccgggagtccggcggcaacggc
ctcccgtcgtatccgcacccgcgccgcctgccctggctgtgggagttcccgacggtgtcg
atgggcctcggcccgctctccgcgatctaccaggcgcgcttcaaccgctacctgacccac
cgcggcatcaaggacgtctccgcctcccacgtctgggccttcctcggcgacggcgagatg
gacgagccggagtcgacggcggcactcgcactggcttcgcgtgaggggctcgacaacctc
accttcgtcatcaactgcaacctccagcgcctcgacggcccggtccgcgcgaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtcaagtcgctg
tggggctcggcgtgggacgagctgttccagctcgacaccacgggtgcgctcgtccgacgg
ctccgcgaggtaccggacgcgcaggtgcagacctaccagacgcgcgacgccgcctacatc
cgccaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctgagcgac
gacaagatcctggagtgcttccacctctcccgcggtggccacgaggcgcgcaaggtgtac
gccgcctacagggccgccgtcgagttcaagggcgccccgacggtcatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaagagcatgcgcgacctgctggagctgccgatccccgac
gcgcagttcgtcgacggggtcgtcccctacggccaccccggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcgggggcccggccccggcccgccgggtccac
cccgtcgccccgctgcccgccccggcggagaaggcgttcgccgccttcgacaagggctcc
ggtacgcagaacgtggcgacgacgatggccttcgtccgtctcatcaaggacctggtccgc
gacaaggacagcggcaggcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagtcgctgttcccctcgctcgggatctactcccccaagggccagacgtacgagccg
gtcgaccgtgaccagctgatgtactacaaggaggccaagaacggccagatcctcaacgag
gggatcaccgaggccggttcgatggccgacttcatcgccgcgtcgacgtcgtacgcgacg
cacggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgtggcttcctcgtcggcgcgacg
gccggccggacgaccctgacgggcgagggcctccagcacgccgacggccactccccggtc
atcgcggccaccaacccggcggcgctgacgtacgaccccgccttcgcgtacgaggtcgcg
gcgatcgtcaaggacggtctgcgccggatgtacggcgaggcggccccgggcgaggaccag
aacgtcttctactacctgaccgtctacaacgagccgctgccgcagcccgcgaagccggcc
ggtaccgccgtcgacgagggcatcgtcaagggcctgtaccgcttcaacaccgccgagtcg
gcgggagtggacgtggcggcggccaacgccccgcgcgtccagctgctgggctccggcacg
gcgatccactgggccctcaaggcacagcggctgctcgccgaggagtggggtgtggccgcc
gacgtgtggtccgcgacctcctggagcgagctgcggcgcgacgcgctggaggcggacgcg
gcgctgctgcgcggcgaggagcgggtgccgtacgtccgtcaggcgctccagggtgccgag
ggtccggtgctggcggtctccgactacatgcgccaggtccccgaccagatcgcgcagtgg
gtcgagcaggactactcctcgctgggcgcggacggcttcggcctctccgacacccgcgag
gccgcccgccgccacttcggcgtcgacgccgagtccgtcgtcgtcgcggccctcgcccag
ctcgcccgccgcggcgaggtcaaggcgacggccgtgaaggaagcgcgcgcgaagtacggc
ctgtag
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