Streptomyces lincolnensis: SLINC_2718
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Entry
SLINC_2718 CDS
T04801
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sls
Streptomyces lincolnensis
Pathway
sls00010
Glycolysis / Gluconeogenesis
sls00020
Citrate cycle (TCA cycle)
sls00620
Pyruvate metabolism
sls00785
Lipoic acid metabolism
sls01100
Metabolic pathways
sls01110
Biosynthesis of secondary metabolites
sls01120
Microbial metabolism in diverse environments
sls01200
Carbon metabolism
sls01210
2-Oxocarboxylic acid metabolism
Module
sls_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sls00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SLINC_2718
00020 Citrate cycle (TCA cycle)
SLINC_2718
00620 Pyruvate metabolism
SLINC_2718
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SLINC_2718
Enzymes [BR:
sls01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SLINC_2718
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ANS64942
UniProt:
A0A1B1M956
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Position
3211795..3214542
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERRILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAFLLDRLSEQNLDAFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIFQARMNRYMHAREIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGA
GWNVIKLVWDRTWDPLLAQDRDGLLVNRMNTTPDGQFQTYATETGAYIRDHFFGDDQRLR
AMVENMTDDQILHLGRGGHDHRKIFAAYKAAVEHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKGFRDRLHLPISDQELESGAPPYYHPGRDSEEIQYMHDRRNSLGGYVP
TRVVRSKPLALPEDKTYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGRRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRDLLLAYKESPQGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMSDQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIVQDGLRRMYGTSEEHPHGEDVFYYLTVYNEPIQH
PAEPANVDVEGILKGIHRFSEGTAGSIPAQIMASGVAVPWAVEAQKTLAEEWNVKADVWS
ATSWNELRREAVECEEHNLLHPEEEQRVPWVTRKLTGAEGPFVAVSDWMRSVPDQISRWV
PGTYQSLGADGFGFADTRGAARRHFHIDAQSIVLGVLTELAKAGKVDRSALKQAVDRYQL
LDVSAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaggaaacccaggagtggctcgactccctcgacgccgccgtggacgag
cgcggccgggagcgggcccgctatctgatgctgcggctgatcgagcgggcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacaccatccccaccaagagc
gagccgttcttcccgggcaacgaggagatcgagcgcaggatcctcaacgccacccgctgg
aacgcggccgtgatggtctcgcgcgcccagcggcccggcatcggcgtcggcggccacatc
gccaccttcgcctcctccgcctcgctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccaggtcttcttccagggccacgcctcgccgggcatc
tacgcccgcgcgttcctcctcgaccggctcagcgagcagaacctcgacgccttccggcag
gagaagtcgaaggcgccgtacgggctgtccagctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtgtcgatgggccttggcccgatcggcgcgatcttccaggcc
cggatgaaccgctacatgcacgcgcgcgagatcgcggacacctcgaagtcgcatgtgtgg
gcgttcctgggcgacggcgagatggacgagcccgagtcgctcggccagctgtccatcgcc
gcccgtgagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcggctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgatcttccggggcgcc
ggctggaacgtcatcaagctggtgtgggaccgcacctgggacccgctgctcgcccaggac
cgcgacggtctgctggtcaaccggatgaacaccacgccggacggccagttccagacgtac
gccaccgagaccggcgcgtacatccgcgaccacttcttcggtgacgaccagcggctgcgc
gcgatggtcgagaacatgaccgacgaccagatcctgcacctggggcgcggcggccacgac
caccggaagatcttcgcggcgtacaaggcggccgtcgagcacaagggccagccgacggtc
atcctcgccaagaccatcaagggctggacgctcggtcccaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagggcttccgcgaccggctgcac
ctgccgatctccgaccaggagctggagtccggcgcgccgccgtactaccacccgggccgg
gactcggaggagatccagtacatgcacgaccggcgcaactcgctgggcgggtacgtgccg
acgcgtgtggtgcgctcgaagccgctcgcgctgcccgaggacaagacgtacgcgaccgtg
aagaagggctccgggcagcagtcgatcgccaccaccatggccttcgtgcgtctactcaag
gacctcatgcgggacaaggagatcggcaggcggttcgtgctgatcgcgccggacgagtac
cgcacgttcggcatggactccttcttccccagtgcgaagatctacaacccgctcggccag
cagtacgaggccgtggaccgggatctgctgctcgcgtacaaggagtcgccgcagggtcag
atgctgcacgacggcatctccgaggccggctgcacggcctcgctgatcgcggcgggttcg
gcgtacgccacgcacggcgagccgctcatcccggtgtacgtcttctactcgatgttcggg
ttccagcgcaccggcgaccagttctggcagatgtcggatcagttggcgcgcggtttcgtc
ctgggtgcgaccgcggggcgtacgacgctgaccggtgaggggctccagcacgccgacggc
cactcgcagttgctcgcgtcgaccaacccgggctgtgtggcgtacgacccggcgttcggg
ttcgagatcgcgcacatcgtgcaggacggtctgcgccggatgtacggcacgtccgaggag
cacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagccgatccagcac
ccggccgagcctgcgaacgtggacgtcgagggcatcctcaagggcatccaccgcttcagc
gagggcacggcgggctcgatcccggcgcagatcatggcgtcgggtgtcgcggtcccgtgg
gccgtcgaggcgcagaagaccctcgccgaggagtggaacgtgaaggccgacgtgtggtcg
gcgacctcctggaacgagctgcggcgcgaggccgtggagtgcgaggagcacaatctgctg
cacccggaggaggagcagcgggtgccgtgggtgacccggaagctgaccggcgcggagggt
ccgttcgtggccgtgtccgactggatgcgatcggttccggaccagatctcgcggtgggtg
ccggggacgtaccagtcgctgggcgcggacggtttcggcttcgcggacacccgtggggcg
gcccgccggcacttccacatcgacgcgcagtcgatcgtgctgggtgtgctgaccgagctg
gccaaggcgggcaaggtggaccggtcggcgctgaagcaggccgtcgaccgctaccagctg
ctcgacgtctcggccgcggatccgggggccgcgggcggcgacgcgtag
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