KEGG   Streptomyces lividans: SLIV_12950
Entry
SLIV_12950        CDS       T03222                                 
Name
(GenBank) Actinorhodin polyketide putative beta-ketoacyl synthase 1
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
slv  Streptomyces lividans
Pathway
slv00253  Tetracycline biosynthesis
slv01056  Biosynthesis of type II polyketide backbone
slv01100  Metabolic pathways
slv01110  Biosynthesis of secondary metabolites
Module
slv_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:slv00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    SLIV_12950
   00253 Tetracycline biosynthesis
    SLIV_12950
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:slv01004]
    SLIV_12950
   01008 Polyketide biosynthesis proteins [BR:slv01008]
    SLIV_12950
Enzymes [BR:slv01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     SLIV_12950
    2.3.1.260  tetracycline polyketide synthase
     SLIV_12950
Lipid biosynthesis proteins [BR:slv01004]
 Polyketide synthase
  Component type
   SLIV_12950
Polyketide biosynthesis proteins [BR:slv01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     SLIV_12950
    Nonaketide PKS
     SLIV_12950
    Decaketide PKS
     SLIV_12950
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N
Other DBs
NCBI-ProteinID: AIJ13579
LinkDB
Position
complement(2964944..2966218)
AA seq 424 aa
MKRRVVITGVGVRAPGGNGTRQFWELLTSGRTATRRISFFDPSPYRSQVAAEADFDPVAE
GFGPRELDRMDRASQFAVACAREAFAASGLDPDTLDPARVGVSLGSAVAAATSLEREYLL
LSDSGRDWEVDAAWLSRHMFDYLVPSVMPAEVAWAVGAEGPVTMVSTGCTSGLDSVGNAV
RAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHASRPFDGTRDGFVLAEG
AAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTGLKADGREMAETIRVALDESRTDA
TDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHSLGAIGSLEIAACV
LALEHGVVPPTANLRTSDPECDLDYVPLEARERKLRSVLTVGSGFGGFQSAMVLRDAETA
GAAA
NT seq 1275 nt   +upstreamnt  +downstreamnt
ttgaagcgcagagtcgtcatcacgggcgtcggcgtccgcgcccccggcgggaacggcacc
cggcagttctgggaactgctcacctcggggcggacggcgacgcgccggatctcgttcttc
gacccctcgccctaccgttcacaggtcgcggcggaggccgacttcgacccggtcgccgag
ggcttcggcccgcgggagctcgaccggatggaccgggcctcgcagttcgccgtggcctgt
gcccgggaggcgttcgccgccagcgggctcgacccggacaccctcgaccccgcccgggtc
ggggtcagcctcggcagcgcggtggcagcggcgaccagcctggagcgcgagtatctgctg
ctgtcggactccggccgtgactgggaggtcgacgcggcctggctgtcccgacacatgttc
gactacctggtgcccagcgtcatgccggccgaggtcgcctgggcggtcggcgccgagggc
ccggtcacgatggtctccaccggctgcacctcgggcctggactccgtcggcaacgcggtc
cgggcgatcgaggagggcagcgccgacgtgatgttcgcgggagccgccgacaccccgatc
accccgatcgtcgtcgcctgcttcgacgcgatccgcgccacgacggcgcgcaacgacgac
ccggagcacgcctcgcggccgttcgacggtacgcgcgacggcttcgtgctggccgaagga
gccgcgatgttcgtcctggaggactacgacagcgcgctggcccgcggagcccgcatccac
gccgagatctcggggtacgcgacgcgctgcaacgcgtaccacatgacgggcctgaaggcc
gacggccgcgagatggccgagaccatccgggtcgccctcgacgagtcccgcacggacgcg
acggacatcgactacatcaacgcgcacggctccggcacccggcagaacgaccgccacgag
acagcggcgtacaagcgcgccctcggcgaacacgcccggcgcactccggtcagctcgatc
aagtcgatggtcggccactcgctgggcgcgatcggctcgctggagatcgcggcctgcgta
ctcgccctcgaacacggcgtggtgcccccgaccgccaacctgcgcaccagcgaccccgag
tgcgatctcgactacgttccgctggaggccagggagcggaagctgcggtccgtactcacc
gtgggcagcggcttcggcggcttccagagcgcgatggtgctgcgcgacgccgagaccgcg
ggggcggccgcatga

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