Streptomyces lavendulae subsp. lavendulae: SLAV_29220
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Entry
SLAV_29220 CDS
T05314
Symbol
metH2
Name
(GenBank) Methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
slx
Streptomyces lavendulae subsp. lavendulae
Pathway
slx00270
Cysteine and methionine metabolism
slx00450
Selenocompound metabolism
slx00670
One carbon pool by folate
slx01100
Metabolic pathways
slx01110
Biosynthesis of secondary metabolites
slx01230
Biosynthesis of amino acids
slx04980
Cobalamin transport and metabolism
slx04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
slx00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SLAV_29220 (metH2)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SLAV_29220 (metH2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SLAV_29220 (metH2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SLAV_29220 (metH2)
04980 Cobalamin transport and metabolism
SLAV_29220 (metH2)
Enzymes [BR:
slx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SLAV_29220 (metH2)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ATZ27629
UniProt:
A0A2K8PLM0
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Position
6532137..6535649
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AA seq
1170 aa
AA seq
DB search
MASLPNPPADTQTRADALREALATRVVVADGAMGTMLQAQDPTMEDFQQLEGCNEVLNVT
RPDIVRSVHEAYYSVGVDCVETNTFGANFAALAEYDIPERNFELSEAGARIAREVADEFT
ASTGQQRWVLGSIGPGTKLPTLGHITYAQIRDAYQINAEGLISGGADALLVETTQDLLQT
KSSIIGARRAMEALGVSVPLICSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATG
PAEMSEHLRYLARNARIPLSCMPNAGLPVLTKQGAHYPLSAPELADAQETFVREYGLSLV
GGCCGTTPEHLRQVVERVRGTAVTARSPQPEPGAASLYQTVPFRQDTSYMAIGERTNANG
SKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMQELAGRFATASTLP
IVLDSTEVPVIQAGLEKLGGRAVINSVNYEDGDGPESRFAKVTQLAREHGAALIALTIDE
EGQARTVGHKVAIAERLIADLTGNWGIRESDILIDTLTFTICTGQEESRKDGIATIESIR
ELKRRHPDVQTTLGLSNISFGLNPAARVLLNSVFLDECVKAGLDSAIVHASKILPIARFD
EEQVTTALDLIYDRREGDYDPLQKLMALFEGVNTKSLKAGRAEELLALPLDERLQRRIID
GEKNGLEADLDEALRTRPALDIVNDTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTAVA
YLEPHMEKTDDEGKGTIVLATVRGDVHDIGKNLVDIILTNNGYNVVNIGIKQPVSAILEA
AQEHKADVIGMSGLLVKSTVIMKENLEELNQRKLAADYPVILGGAALTRAYVEQDLHEIY
EGEVRYARDAFEGLRLMDALIAVKRGVPGAALPELKQRRVAKRTSPALQEEEPQEPGGRS
DVAVDNPVPTPPFWGTRVVKGIPLKDYASWLDEGALFKGQWGLKQARAGGATYEELVESE
GRPRLRGLLEKLHTENLLEAAVVYGYFPCVSKGDDLIILDEQGNERTRFTFPRQRRGRRL
CLADFFRPEESGETDVVGLQVVTVGSKIGEATAKLFESDSYREYLELHGLSVQLAEAMAE
YWHARVRAELGFGGEDPAAVEDMFDLKYRGARFSLGYGACPDLEDRAKIADLLQPERIGV
HLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3513 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgttgccgaacccgcccgctgacacccagacccgggccgatgccctccgggag
gcgctcgcgacccgtgtggtcgtcgccgacggagccatgggaacgatgctccaggcgcag
gaccccacgatggaggacttccagcagctcgaaggctgcaacgaggtcctgaacgtgacg
cgccccgacatcgtgcgctccgtccacgaggcgtactactcggtgggtgtggactgcgtc
gagacgaacaccttcggtgcgaacttcgcggcgctcgccgagtacgacattcccgagcgg
aacttcgagctgtcggaggccggtgcgcggatcgcgcgtgaggtggcggacgagttcacc
gcttcgacgggtcagcagcggtgggtgctgggttccatcggcccgggcaccaagcttccc
accctgggccacatcacttacgcgcagatccgtgacgcctatcagatcaatgcggagggt
ctgatctccggcggggcggatgccctgctggtggagaccacgcaggacctgctgcagacg
aagtcctcgatcatcggtgcccggcgcgcgatggaggccctcggggtcagcgttccgctg
atctgctccgtcaccgtcgagaccaccggcacgatgctcctgggttcggagatcggcgcg
gcgctgacggcgttggagccgctggggatcgacatgatcggtctgaactgcgcgaccggc
cccgcggagatgagtgagcacctgcgctacctggcgcgcaacgcccgtatcccgctgtcc
tgcatgccgaacgcgggtctgccggtgctgacgaagcagggtgcgcactatccgctgtcg
gctcctgagctggcggatgcgcaggagacgttcgtgcgtgagtacggtctgtctctggtc
ggcggctgctgtggcaccactccggagcatctgcggcaggtggtggagcgggtgcgtggc
acggccgtcaccgcgcgcagcccgcagcccgagccgggtgccgcttcgctgtatcagacg
gtgccgttccggcaggacacctcgtacatggcgatcggtgagcggacgaacgcgaacggg
tcgaagaagttccgtgaggcgatgctggaggcgcgctgggacgactgtgtggagatggcc
cgggaccagatccgtgagggcgcgcacatgctcgatctgtgtgtggactacgtcgggcgt
gacggtgtcgcggacatgcaggaactcgccgggcgtttcgcgaccgcctcgacgctgccg
atcgtgctggactccaccgaggttccggtgatccaggccggtctggagaagctgggcggg
cgtgcggtcatcaactcggtcaactacgaggacggtgacgggcccgagtcccgcttcgcg
aaggtcacgcagctggcgcgggagcacggtgccgcgctgatcgcgctgacgatcgacgag
gagggccaggcccgcacggtcgggcacaaggtcgccatcgccgagcgtctcatcgccgac
ctgacggggaactgggggatccgcgagtcggacatcctcatcgacacgctcacgttcacg
atctgcacggggcaggaggagtcccgtaaggacggcatcgcgacgatcgagtcgatccgt
gagctcaagcgccgccaccccgacgtgcagaccaccctcggtctgtcgaacatctccttc
ggcctgaacccggccgcgcgtgtcctgctgaactccgtgttcctcgacgagtgtgtgaag
gcgggtctggattcggcgatcgtgcacgcgtcgaagatcctgccgatcgcccggttcgac
gaggagcaggtcaccaccgccctggatctgatctacgaccgccgtgagggtgactacgac
ccgctgcagaagctgatggccctcttcgagggcgtcaacaccaagtccctgaaggccggc
cgcgccgaggaactcctcgccctgccgctggatgaacgcctccagcgccgcatcatcgac
ggcgagaagaacggtctggaggccgacctcgacgaagccctgcggacacgcccggccctg
gacatcgtcaacgacacgctcctggaaggcatgaaggtcgtcggtgagctgttcggctcc
ggccagatgcagctgcccttcgtcctgcagtcggcggaggtgatgaagacggccgtcgcc
tacctcgaaccgcacatggagaagacggacgacgagggcaagggcacgatcgtgctggcc
accgtccgcggggacgtccacgacatcgggaagaacctcgtcgacatcatcctgacgaac
aacggctacaacgtcgtcaacatcgggatcaagcagccggtctccgcgatcctggaggcc
gcgcaggaacacaaggccgacgtgatcggcatgtcgggtctcctggtcaagtccaccgtg
atcatgaaggagaacctggaggagctcaaccagcgcaagctggccgcggactaccccgtc
atcctcggcggcgccgccctcacccgcgcctacgtcgaacaggacctccacgagatctac
gaaggcgaagtccgctacgcacgcgacgccttcgaaggcctccgcctcatggacgccctc
atcgccgtcaagcgaggcgtccccggtgccgccctccccgagctcaagcagcgccgcgtc
gccaagcggaccagccccgccctccaggaggaggagccgcaggagccgggcggccgctcc
gacgtggccgtcgacaatcccgtccccacgccgcccttctggggcacccgcgtggtcaag
ggcatcccgctcaaggactacgcctcctggctggacgagggcgccctgttcaagggccag
tggggtctgaagcaggcccgcgcgggcggtgccacgtacgaggagctcgtcgagagcgag
ggccgtccacgcctgcgcggcctcctggagaagctgcacaccgagaacctgctcgaagcg
gcggtcgtctacggctacttcccctgcgtctccaagggcgacgacctgatcatcctcgac
gagcagggcaacgagcggacccgcttcaccttccctcgccagcgccgcggccggcgcctg
tgcctcgcggacttcttccgccccgaggagtccggcgagaccgacgtggtcggcctccag
gtggtcaccgtgggttcgaagatcggcgaggccaccgccaagctgttcgagtccgactcc
taccgcgagtacctggagctgcacggcctgtccgtccagctcgccgaggccatggccgag
tactggcacgcccgcgtccgcgccgagctcggcttcggcggcgaggacccggccgccgtg
gaggacatgttcgacctcaagtaccggggagcccgcttctccctcggctacggcgcctgc
cccgacctggaggaccgggcgaagatcgccgacctcctccagccggagcggatcggcgtc
cacctctcggaggagttccagctccaccccgagcagtccaccgacgccatcgtgattcac
caccccgaagcgaagtatttcaacgcacgctga
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