Streptomyces avermitilis: SAVERM_2376
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Entry
SAVERM_2376 CDS
T00126
Symbol
pks9-4
Name
(GenBank) putative 3-oxoacyl-ACP synthase I
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00253
Tetracycline biosynthesis
sma01056
Biosynthesis of type II polyketide backbone
sma01100
Metabolic pathways
sma01110
Biosynthesis of secondary metabolites
Module
sma_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
SAVERM_2376 (pks9-4)
00253 Tetracycline biosynthesis
SAVERM_2376 (pks9-4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
sma01004
]
SAVERM_2376 (pks9-4)
01008 Polyketide biosynthesis proteins [BR:
sma01008
]
SAVERM_2376 (pks9-4)
Enzymes [BR:
sma01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
SAVERM_2376 (pks9-4)
2.3.1.260 tetracycline polyketide synthase
SAVERM_2376 (pks9-4)
Lipid biosynthesis proteins [BR:
sma01004
]
Polyketide synthase
Component type
SAVERM_2376 (pks9-4)
Polyketide biosynthesis proteins [BR:
sma01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
SAVERM_2376 (pks9-4)
Nonaketide PKS
SAVERM_2376 (pks9-4)
Decaketide PKS
SAVERM_2376 (pks9-4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
BAC70087
UniProt:
Q79ZF4
LinkDB
All DBs
Position
complement(2900251..2901483)
Genome browser
AA seq
410 aa
AA seq
DB search
MRAPGGGNAKEFWELISSGTSAIRTISLFDASGFRSRIAGECDFDPVAEGFSAQEIRRMD
RSAQLAVAATREAVADAGLDLAETDPHRCGVSVGSAIGGTMSLDREYNVLSDGGRKWLLD
HEYAVPHMYNYLVPTSIAADVAWTVGAEGPVSLVSTGCTAGIESVSHAARLIREGSADVM
LAGGSDASLSPICVACFDAIKATTPRNDEPATASRPFDRTRNGFVLAEGSAMLVLEELNH
ARERGARVYAEIGGWDVRANAYHMTGLRTEGPELAKAIEVALRMAGRVPEQVDYVNAHGS
GTKQNDAHETDAFKRTLGDHAYRTPVSSIKSMIGHSLGAIGSIEIAACALAIDAGLIPPT
ANLHEPDPELGLDYVPLSARQADLRTVLKVGSGFGGFQSAMVLTQGGSDE
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
gtgcgcgccccgggcggaggaaacgccaaggagttctgggagctgatctcctccggcacc
tcggccatacgcaccatctcgctcttcgacgcgtccgggttccgctcccggatcgcgggc
gagtgcgatttcgacccggtcgcggagggcttctccgcgcaggagatccggcgcatggac
cggagcgcgcagctcgccgtcgccgcgaccagggaagccgtcgcggacgccggactcgac
ctggccgagacggacccgcatcgctgcggggtcagcgtcggcagcgccatcggcggcacg
atgagcctggaccgggagtacaacgtgctctccgacggcggccgcaagtggctccttgac
cacgagtacgcggtgccgcacatgtacaactatctcgtcccgacgtcgatcgccgcggac
gtggcctggacggtcggggcggaaggccccgtgtccctggtgtccacgggatgcaccgcg
ggcatcgagtcggtgtcccacgcggcgcggctgatccgcgagggctccgccgacgtgatg
ctggccggcggctcggacgcgtccctctcaccgatctgcgtcgcctgcttcgacgcgatc
aaggcgacgacgccgcgcaacgacgaaccggccaccgcgtcccgcccgttcgaccgcacc
cggaacggcttcgtgctcgccgaaggcagcgcgatgctggtgctggaagagctgaaccac
gccagggaacgcggcgcgcgcgtctacgcggagatcggcggatgggacgtgcgcgccaac
gcgtaccacatgaccggactcaggaccgagggcccggaactggccaaggccatcgaggtg
gcgctgcggatggccgggcgggtgcccgagcaggtcgactacgtgaacgcgcacggctcc
ggtacgaagcagaacgacgcgcacgagaccgacgcgttcaagcgcactctcggcgaccac
gcctaccggacgccggtcagttcgatcaagtccatgatcgggcactcgctgggcgcgatc
ggctcgatcgagatcgcggcatgcgcgctggccatcgacgccgggctcattccgccgacc
gccaacctgcacgaacccgacccggaactggggctcgactacgtgccgctgtcggcgcga
caggcggacctgcggacggtgctcaaggtcggcagcgggttcggcggtttccagagcgcc
atggtgctgacccaggggggatccgatgagtag
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