Streptomyces avermitilis: SAVERM_2972
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Entry
SAVERM_2972 CDS
T00126
Symbol
sucA
Name
(GenBank) putative 2-oxoglutarate dehydrogenase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00020
Citrate cycle (TCA cycle)
sma00630
Glyoxylate and dicarboxylate metabolism
sma00785
Lipoic acid metabolism
sma01100
Metabolic pathways
sma01110
Biosynthesis of secondary metabolites
sma01120
Microbial metabolism in diverse environments
sma01200
Carbon metabolism
sma01210
2-Oxocarboxylic acid metabolism
Module
sma_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sma_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SAVERM_2972 (sucA)
00630 Glyoxylate and dicarboxylate metabolism
SAVERM_2972 (sucA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SAVERM_2972 (sucA)
Enzymes [BR:
sma01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SAVERM_2972 (sucA)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SAVERM_2972 (sucA)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SAVERM_2972 (sucA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SAVERM_2972 (sucA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BAC70683
UniProt:
Q82J10
LinkDB
All DBs
Position
3724011..3727841
Genome browser
AA seq
1276 aa
AA seq
DB search
MSPQSPSNSSISTDDQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPG
AAAASAPAGTAAAGAAETTTPAPAAPTAAAPAAPAAPAPAAPAPAPAAPAPAAAPAVPKP
AAAAPAPAAAKPAAAAPAQPKAAAATEAAEGPTFVPLRGPAAAVAKNMNASIEVPTATSV
RAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWHYAEKDGKPTL
VKPAHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDF
TGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTL
TSTYDHRVIQGAASGEFLRIVANFLLGEGGFYDEIFEALRIPYEPVRWLKDIDASHDDDV
TKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGK
SLMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERSHSKPEREEQLRILRRLN
AAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLA
NIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGASGTFTGLDGEQIKVSLAANPSHLET
VDPIIEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTV
HIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFN
KDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQA
LQDFQGQLEKVFTEVREAISTPGEAPAPEPQPEFPVAVPTAVSQEVVKRIAESQVNIPDH
VTVHPRLLPQLQRRAAMIEDDTIDWGMGETLAIGSLLLEGTPVRLSGQDSRRGTFGQRHA
VLIDRVTGEDFTPLQYLADDQARLNVYDSLLSEYAVMGFEYGYSLARPDALVMWEAQFGD
FVNGAQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTV
AQPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTTGAFRPVIGDDTV
DAAAVRKVVFCAGKLYYDLEAERKKRGATDAAAAETAIIRLERLYPLPGAELQAEIAKYP
NAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAK
RHQAEQEQLVREVFEA
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacgaccaagccgggaagaac
cccgctgcggccttcggacccaacgagtggctcgtcgacgagatctatcagcagtacctc
caggacccgaattcggtagaccgagcctggtgggacttcttcgccgattacaagccgggc
gcagctgccgcctcggctccggcgggtactgcggccgcgggggccgcagagaccaccacg
ccggctccggccgcgccgaccgctgcggcccccgccgctcccgcggcaccggctccggcc
gccccggcaccggctccggccgctccggctcccgcggccgctccggcggtcccgaagccc
gctgccgcggctccggccccggccgccgcgaagccggccgccgccgcgcccgcccagccg
aaggccgccgcggcgaccgaggccgccgagggccccacgttcgtcccgctgcgcggtccc
gccgccgcggtcgcgaagaacatgaacgcctcgatcgaggtgcccacggccacgtccgtg
cgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctgaag
cgtgcccggggcgggaagatctccttcacccacctcatcgggtacgcgatggtgcaggcc
atcaaggccatgccgtcgatgaactggcactacgcggagaaggacgggaagcccaccctc
gtcaagcccgcgcacgtcaacttcggcctcgccatcgacctggtgaagcccaacggcgac
cgccagctcgtcgtcgccggcatcaagaaggccgagacgctgaacttcttcgagttctgg
caggcctacgaggacatcgtccgccgcgcccgtgacggcaagctgacgatggacgacttc
accggtgtcacggtctccctgaccaaccccggcggcctcggcaccgtccactcggtcccg
cgtctgatgcccggccagtcggtcatcatgggcgtcggctccatggactacccggcggag
ttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatgacgctc
acgtcgacctacgaccaccgggtgatccagggcgccgcgtccggcgagttcctgcggatc
gtcgcgaacttcctcctcggcgagggcggcttctacgacgagatcttcgaggctctgcgg
atcccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtc
acgaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatg
gccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctggacatcaccgag
cacggcctcacgctctgggacctggagcgcgagttcgcggtcggcggcttcgcgggcaag
tccctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccacc
ggcatcgagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcatc
gagcgctcgcactccaagccggagcgcgaggagcagctgcgcatcctgcgccgcctgaac
gcggcggaggccttcgagaccttcctccagacgaagtacgtcggccagaagcgcttctcc
ctggagggcggcgagtccgtcatcccgctgctggacgcggtcatcgactccgccgccgag
tcccgcctggacgaggtcgtcatcggcatggcccaccgcggccgcctgaacgtgctcgcc
aacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccg
aagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccagcggcaccttcacc
ggcctggacggcgagcagatcaaggtctcgctggccgccaacccgtcccacctggagacg
gtcgacccgatcatcgagggcatcgcccgcgccaagcaggacatcatcaacaagggcggc
acggacttcacggtcctgccggtcgccctgcacggtgacgcggccttcgcgggccagggc
gtggtggccgagaccctgaacatgtcgcagctgcgcggttaccgcacgggcggcacggtc
cacatcgtcatcaacaaccaggtcggcttcacggccgccccggagtcgtcgcgttcgtcg
atgtacgcgaccgatgtggcccgcatgatcgaggcgccgatcttccacgtgaacggcgac
gaccccgaggccgtcgtccgcgtcgcccgcctggccttcgagttccgccaggcgttcaac
aaggacgtcgtcatcgacctgatctgctaccgccgtcggggccacaacgagtccgacaac
ccggcgttcacgcagcccctgatgtacgacctgatcgacaagaagcgctcggtgcgcaag
ctctacaccgagtccctgatcggccggggcgacatcacgctggaagaggcggagcaggcg
ctccaggacttccagggccagctggagaaggtcttcaccgaggtccgcgaggccatctcc
accccgggcgaggcgccggctcccgagccgcagcccgagttcccggtggccgtgccgacc
gcggtctcccaggaggtcgtgaagcggatcgccgagtcccaggtcaacatccccgaccac
gtcaccgtgcacccgcggctgctgccgcagcttcagcgccgtgcggcgatgatcgaggac
gacacgatcgactggggcatgggcgagaccctggccatcggctcgctgctcctcgagggc
accccggtccgtctttcgggccaggactcccgccggggcacgttcggccagcgccacgcc
gtcctgatcgaccgggtcacgggcgaggacttcaccccgctccagtacctcgcggacgac
caggcgcgcctgaacgtctacgactccctgctctccgagtacgcggtcatgggcttcgag
tacggctactcgctggcccgccccgacgccctcgtgatgtgggaggcgcagttcggtgac
ttcgtcaacggcgcgcagacggtcgtcgacgagtacatctcggccgccgagcagaagtgg
ggccagacgtccggcgtcaccctgctcctcccgcacggctacgagggccagggtccggac
cactcctcggcccgtatcgagcgcttcctccagctgtgcgcgcagaacaacatgacggtc
gcccagccgacgctcccgtcgaactacttccacctcctgcggtggcaggtgcacaacccg
caccacaagccgctggtggtcttcaccccgaagtcgatgctgcgcctcaaggccgccgcc
tcgaagacggaggagttcaccacgggcgccttccgccccgtcatcggcgacgacaccgtc
gacgccgccgcggtccgcaaggtcgtcttctgcgccggcaagctgtactacgacctcgag
gccgagcggaagaagcgcggcgccacggacgcagcggctgccgagaccgcgatcatccgc
ctcgagcgcctgtacccgctgccgggtgccgagctccaggcggagatcgccaagtacccg
aacgccgagaagtacctgtgggcccaggaggagccggcgaaccagggcgcatggcccttc
atcgccctcaacctgatcgaccacctggacctggcggtcggcgcggacgttccgcacggg
gagcgactgcggcgcatctcccgcccgcacagctcttcgccggccgtgggttccgccaag
cggcaccaggctgagcaggagcagttggtgcgagaggtgttcgaggcgtag
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