Streptomyces avermitilis: SAVERM_6020
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Entry
SAVERM_6020 CDS
T00126
Symbol
aceE2
Name
(GenBank) putative pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00010
Glycolysis / Gluconeogenesis
sma00020
Citrate cycle (TCA cycle)
sma00620
Pyruvate metabolism
sma00785
Lipoic acid metabolism
sma01100
Metabolic pathways
sma01110
Biosynthesis of secondary metabolites
sma01120
Microbial metabolism in diverse environments
sma01200
Carbon metabolism
sma01210
2-Oxocarboxylic acid metabolism
Module
sma_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SAVERM_6020 (aceE2)
00020 Citrate cycle (TCA cycle)
SAVERM_6020 (aceE2)
00620 Pyruvate metabolism
SAVERM_6020 (aceE2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SAVERM_6020 (aceE2)
Enzymes [BR:
sma01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SAVERM_6020 (aceE2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF5576
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BAC73732
UniProt:
Q82AN6
LinkDB
All DBs
Position
complement(7246738..7249440)
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AA seq
900 aa
AA seq
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MTDPTAIQPSELDQLPDRDPEETAEWQASLDAVTQAAGPHRAAYLMRRTLERAEGNGIAL
PKLLETDYVNTIPTSAEPVVDGDEEMEHRITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFRGKEADGSGDQLYIQGHASPGIYARAFLDGRLTEHHLDHFRQESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTSRGIKDVSQSHVWAFLGDGEM
DEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTL
WGSAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGADPALVEMAKLIGD
DKILECFHLSRGGHESRKVYAAYRAAVSHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLSTDEFKQMRDLLELPISDSQFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRTH
PLAPLPAPADKTFASFDKGSGSQNVATTMAFVRLVKDLVRDKQTGRRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGSMADFIAASTAYST
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEIAVIVKDGLRRMYGEAAPGEDPNVFYYLTVYNEPVPQPAKPA
GLGIDEGIVKGLYRFNTAESADLSPAANAPRIQLLGSGTAIHWVLQAQRLLAEEWGVAAD
VWSATSWTELRRDALEADAALLRGEERVPFVRQALHGAEGPVLAVSDYMRQVPDQIAQWV
EQDYSSLGADGFGLSDTRDAARRHFGVDAESIVVAALAQLARRGEVKATAVKEARERYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaccgcaatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgagtggcaggcctccctggacgccgtcacccaggcggccgggccgcac
cgtgccgcgtacttgatgcgccgcacactggagcgcgccgagggcaacggcatcgcgctg
ccgaagctgctcgagacggactacgtcaacaccatccccacctccgccgagcccgtcgtg
gacggcgacgaggagatggagcaccggatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccggggcagcaaatacggcgtgggcggccacatcgccaccttcgcctccgcc
gcctggctgtacgagaccggcttcaaccacttcttcaggggcaaggaggcggacggttcc
ggtgaccagctctacatccagggccacgcctccccgggcatctacgcccgcgccttcctc
gacggccggctgaccgagcaccacctcgaccacttccgccaggagtccggcggcaacggt
ctgccgtcgtacccgcacccgcgccgtctcccctggctgtgggagttcccgacggtgtcg
atgggcctcggcccgctctccgcgatctaccaggcgcgcttcaaccgctacctgaccagc
cgcggcatcaaggacgtctcgcagtcccacgtgtgggcgttcctcggcgacggcgagatg
gacgagcccgagtcgaccgcggcactcgccctggcctcccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctccagcgcctcgacggcccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggtgccggctggaacgtcgtcaagacgctg
tggggctcggcctgggacgagctgttccagctcgacaccacgggcgccctcgtacgccgc
ctgcgcgaggtaccggacgcgcaggtgcagacgtaccagacccgcgacgccgcctacatc
cgccaggacttcttcggcgccgacccggccctcgtcgagatggcgaagctgatcggcgac
gacaagatcctcgagtgtttccacctctcccgcggtggtcacgagtcgcgcaaggtctac
gcggcctacagggcggccgtgtcccacaagggcgcgccgacggtgatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgtcgacggacgagttcaagcagatgcgtgacctgctggaactgcccatctccgac
agccagttcgtcgacggcgtggtgccctacggccacccgggcgccgactcccccgaggtc
cgctaccttcaggagcgccgcgcggccctcggcggcccggccccggcccgccgtacgcac
ccgctggccccgctgccggcccccgccgacaagacgttcgcgtccttcgacaagggctcc
ggctcgcagaacgtggcgacgacgatggcgttcgtccggctggtcaaggacctggtccgc
gacaagcagaccggccggcgctgggtgccgatcgtgccggacgaggcccgtaccttcggt
atggagtcgctcttcccgtccctcggcatctattcgccgaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaaggacggccagatcctcaacgag
gggatcaccgaggccggctccatggcggacttcatcgccgcgtccaccgcgtactccacg
cacggcgaagcgatgatccccttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctgggccgcggcttcctggtcggcgcgacg
gccggccgtacgacgctgacgggtgagggcctccagcacgcggacggccactcgccggtc
atcgccgcgaccaacccggcggcgctgacgtacgacccggcgttcgcgtacgagatcgcg
gtcatcgtcaaggacggtctgcgccgtatgtacggcgaggcggccccgggcgaggacccg
aacgtcttctactacctcaccgtctacaacgagccggtgccgcagcccgcgaagccggcc
ggcctcggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacacggccgagtcg
gcggacctgtcccccgccgccaacgccccgcgcatccagctgctgggctccggcacggcg
atccactgggtgcttcaggcgcagcggctgctcgccgaggagtggggtgtggccgccgac
gtgtggtccgcgacctcctggaccgagctgcggcgcgacgcgctcgaggccgacgcggcg
ctgctgcgcggcgaggagcgggtgccgttcgtccgccaggcgctgcacggcgccgagggc
ccggtgctcgcggtctccgactacatgcgtcaggtcccggaccagatcgcgcagtgggtc
gagcaggactactcgtcgctcggtgcggacggcttcggcctctccgacacccgtgacgcg
gcccgccgtcacttcggcgtggacgcggagtcgatcgtcgtcgcggccctggcccagctc
gccaggcgcggcgaggtcaaggccacggcggtgaaggaggcgcgggagcgctacggcctg
tag
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