Streptomyces malaysiensis: SMALA_2106
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Entry
SMALA_2106 CDS
T05189
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
smal
Streptomyces malaysiensis
Pathway
smal00010
Glycolysis / Gluconeogenesis
smal00020
Citrate cycle (TCA cycle)
smal00620
Pyruvate metabolism
smal00785
Lipoic acid metabolism
smal01100
Metabolic pathways
smal01110
Biosynthesis of secondary metabolites
smal01120
Microbial metabolism in diverse environments
smal01200
Carbon metabolism
smal01210
2-Oxocarboxylic acid metabolism
Module
smal_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SMALA_2106
00020 Citrate cycle (TCA cycle)
SMALA_2106
00620 Pyruvate metabolism
SMALA_2106
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SMALA_2106
Enzymes [BR:
smal01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SMALA_2106
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ATL82340
UniProt:
A0A291SND4
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Position
2747365..2750040
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AA seq
891 aa
AA seq
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MTDLVRTQPSALDQLPDRDPEETAEWGASLDAVARAAGSHRASYLMRRTLERAESAGLAL
PPLLESDYLNTIPTAAEPAFPGDEAMERRITAWNRWNAAAMVTRGSRDGLGGHIATFASA
AWLYETGFQHFFRGKEADGSGDQLYIQGHASPGIYARAFLDGRLTERHLDHFRREAGGEG
LPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLAARGIKDTANSHVWAFLGDGEM
DEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRAAGWNVVKSL
WGSAWDELFAQDTTGALVRRLREVPDGQFQTYATRDAAYIREHFFGAEPELARLAQGFTD
AKLAECFHTSRAGHEPRKVYAAYRAAMAHKGAPTVVLAQTVKGWTLGPGFESRNANHQMK
KLTGKEFRAMRDLLELPIPDSKLDEHLVPYVHPGPDSPEVRYLQERRAALGGPAPARRVH
PVALPEPSAKPFETLAKGSGSQEIATTMAFVRLVKDLMREKETGRRWVPIVPDEARTFGM
ESLFPTAGIYSPLGQTYDPVDRDQLLYYKEAANGQILNEGITESGSMADFTAAATSYATH
GEPMIPFYIFYSMFGWQRTADQMWALADQLGRGFLIGATAGRTTMTGEGLQHADGHSPLI
ASTNPAALAYDPAFAYEVGAIVREGLRRMYGPEAEDVFYYLTVYNEPKVQPSMPTGEGVE
EGILKGLYRYREATAPAADSPRIQLLASGTAIHWTLEAQKLLADDWGVAADVWSATSWSE
LRRDALSCDAAQLNGEDRVPYVTRALAGAPGPVLAVSDWMRAVPDQISQWVEQDWYSLGT
DGFGLSDTREAARRHFGVDAPAIVVAALSRLARQGAVPATAPKEAAERYGI
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgaccgatctcgtacgcacgcagccgagtgcgctcgaccagcttcccgaccgtgacccc
gaggagaccgccgaatggggcgcctccctggacgccgtcgcgcgggcggccgggtcacac
cgcgcctcgtacctcatgcgccgcaccctggagcgcgccgagagcgccgggctcgcgctg
ccgcccctgctggagtcggactacctcaacaccatcccgaccgccgccgagcccgcgttc
ccgggcgacgaggccatggagcgccgcatcaccgcctggaaccggtggaacgcggcggcg
atggtcacccgcggcagccgtgacggcctcggcggccacatcgccaccttcgcctccgcc
gcctggctctacgagacgggcttccagcacttcttccgcggcaaggaggcggacggcagc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacgggcggctgaccgagcgccatctggaccacttccgccgcgaggcgggcggcgagggc
ctgccgtcctatccgcatccgcggcggctgccgtggctgtgggagttccccaccgtctcg
atggggctcggcccgatctccgcgatctaccaggcccgtttcaaccgctatctggcggcc
cgtggcatcaaggacaccgccaactcccacgtctgggccttcctcggcgacggcgagatg
gacgagccggagtcgacggccgcgctcgccctggccggccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctccagcgcctcgacggcccggtgcgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcgcggcgggctggaacgtggtcaagtccctg
tggggctccgcctgggacgagctgttcgcgcaggacaccacgggcgcgctggtgcgccgg
ctgcgcgaggtcccggacggccagttccagacgtacgcgacccgcgacgcggcctatatc
cgcgagcacttcttcggcgccgagccggagctggcccggctcgcccaggggttcaccgac
gccaagctggccgagtgtttccacacctcgcgcgcgggccatgagccccgcaaggtgtac
gcggcctaccgcgcggccatggcgcacaagggcgccccgaccgtggtgctcgcccagacc
gtcaagggctggacgctgggccccggcttcgagtcgcgcaacgccaaccaccagatgaag
aagctgacgggcaaggagttccgcgccatgcgggacctcctcgaactccccatcccggac
agcaagctggacgagcacctcgtcccctacgtccaccccggccccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcggcggcccggccccggcccgcagggtccac
ccggtggccctgcccgagccgtccgcgaagccgttcgagacgctcgccaagggctccggc
agccaggagatcgccaccaccatggccttcgtccggctggtcaaggacctgatgcgggag
aaggagaccgggcggcgctgggtgccgatcgtgccggacgaggcacggaccttcggcatg
gagtcgctcttccccaccgccgggatctactccccgctcggccagacctacgacccggtc
gaccgcgatcagctcctgtactacaaggaggccgcgaacggtcagatcctcaacgagggg
atcaccgagtccggttcgatggccgacttcaccgccgccgcgacgtcgtacgcgacccac
ggcgagccgatgatccccttctacatcttctactcgatgttcggctggcagcgcaccgcc
gaccagatgtgggcgctcgccgaccagctcggccgcggcttcctcatcggcgccaccgcc
ggccgtacgacgatgaccggcgagggcctccagcacgccgacggccactccccgctgatc
gcctccaccaacccggcggcgctcgcctacgacccggccttcgcctacgaggtcggcgcg
atcgtgcgggagggtctgcggcggatgtacggccccgaggccgaggacgtcttctactac
ctgacggtctacaacgagcccaaggtccagccgtcgatgcccacgggcgagggcgtcgag
gagggcatcctcaagggcctgtaccgctaccgggaggccacggccccggccgcggactcc
cctcgtatccagctgctcgcctccggcaccgccatccactggacgctggaggcccagaaa
ctcctcgccgacgactggggcgtggccgccgacgtgtggtccgccacctcctggagcgag
ctgcgccgcgacgccctgtcctgtgacgcggcgcagctcaacggcgaagaccgggtcccg
tacgtcacccgtgccctggcaggcgcaccgggcccggtcctcgccgtcagcgactggatg
cgtgccgtccccgaccagatcagccagtgggtcgagcaggactggtactcactgggcacg
gacggcttcggcctctccgacacccgcgaggccgcccgccgccacttcggcgtggatgcc
ccggccatcgtggtggccgcactgtcccggctggcccgccaaggcgcggtcccggccacc
gcgcccaaggaagccgcggagcggtacggcatctga
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