Streptomyces marincola: CAG99_21075
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Entry
CAG99_21075 CDS
T08123
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
smao
Streptomyces marincola
Pathway
smao00010
Glycolysis / Gluconeogenesis
smao00020
Citrate cycle (TCA cycle)
smao00620
Pyruvate metabolism
smao00785
Lipoic acid metabolism
smao01100
Metabolic pathways
smao01110
Biosynthesis of secondary metabolites
smao01120
Microbial metabolism in diverse environments
smao01200
Carbon metabolism
smao01210
2-Oxocarboxylic acid metabolism
Module
smao_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
smao00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CAG99_21075
00020 Citrate cycle (TCA cycle)
CAG99_21075
00620 Pyruvate metabolism
CAG99_21075
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CAG99_21075
Enzymes [BR:
smao01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CAG99_21075
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ARQ70999
UniProt:
A0A1W7D248
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Position
complement(4821682..4824414)
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGDEEIERKILNATRWNAAVTVSRAQRPGIGVGGHI
ATFGSSASLYDVGFNHFFRGKDGGDGGDQVYFQGHASPGIYARAFLLDRLSERHLDGFRQ
ERSKAPYGLSSYPHPRMMPDFWEFPTVSMGLGPISAIYQARMNRYMQARGIADTSNSHVW
AFLGDGEMDEPESLGQLTLAAREGLDNLTFIVNCNLQRLDGPVRGNGKIIQELESVFRGA
GWNVIKLIWDRSWDPLLAQDRDGILVNKLNSTPDGQFQTYATETGAYIRDHFFGGDQRLR
AMVEGLSDDQILHLGRGGHDHRKVYAAYKAAKEHQGQPTVILAQTIKGWMLGPSFEGRNA
THQMKKLTVADLKGFRDRLHLPIPDSELESGLPPYYHPGRDSEEIQYMHDRRRELGGYVP
TRVNRAKPLPQPGDKAYAAVRKGSGQQQVATTMAFVRLLKDLMRDKEIGKRFVPIAPDEY
RTFGMDSLFPSAKIYNPLGQTYESVDRDLLLSYKESPTGQMLHDGITEAGCTASLIAAGS
AYATHGEHLIPIYVFYSMFGFQRTGDQFWQMGDQLARGFVLGATAGRTTLTGEGTQHADG
HSQLLASTNPACVSYDPAFGYEIAHIVRDGLRRMYGENAEDVFYYLTVYNEPINQPAEPE
NVDVEGILKGLYRYREGTGTGTRAQILASGVAVPWAVEAQRILAEEWQVTADVWSATSWN
ELRRDAVEAEEHNLLHPEEEQRVPYVTRKLQGAEGPVVAVSDWMRSVPDQIARWVPGTYQ
SLGGDGFGFADTRGAARRFFHIDAQSIVLGVLTELAKEGKIDRSVLKQAIDRYQLLDVAA
ADPGPAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatcagatcgcaacccgatcatcattggcggccttcccagccaggtcccg
gatttcgaccctgaggagactcaggaatggctcgactcgctcgacgccgccgtcgacgag
cgaggccgggaacgggcccgctatctcatgctccgcctgatcgagcgcgcccgtgagaag
cgggtggccgtgcccgagatgcgcagcacggactacgtcaacacgatcgcgaccaaggat
gagccgttcttccccggcgacgaggagatcgagcgcaagatcctgaacgcgacccgctgg
aacgcggccgtgacggtctcccgcgcccagcgccccggcatcggggtgggtggacacatc
gccaccttcggctcgtcggcgtcgttgtacgacgtcggcttcaaccacttcttccgcggc
aaggacggcggtgacggcggggaccaggtctacttccagggtcacgcctcgcccggcatc
tacgcccgagccttcctcctcgaccggctgtccgagcggcacctggacgggttcaggcag
gagcggtcgaaggccccctacggtctgtccagctacccgcacccgcggatgatgccggac
ttctgggaattcccgaccgtctccatgggcctcggcccgatcagcgccatctaccaggcg
cggatgaaccgctacatgcaggcccgcggcatcgccgacacctcgaactcgcacgtgtgg
gcgttcctcggggacggcgagatggacgagcccgagtcgctcggccagctcacgctcgcg
gcccgcgagggtctcgacaacctcacgttcatcgtcaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacggcaagatcattcaggagctggagtccgtgttccgcggcgcc
ggctggaacgtgatcaagctgatctgggaccgctcctgggacccgctgctcgcgcaggac
cgcgacggcatcctggtcaacaagctgaactccacgcccgacgggcagttccagacctac
gcgaccgagaccggcgcctacatccgcgaccacttcttcggtggcgaccagcggctgcgg
gcgatggtcgagggcctgtccgacgaccagatcctgcacctgggccgcggcgggcacgac
caccgcaaggtctacgcggcgtacaaggcggccaaggagcaccagggccagccgacggtg
atcctcgcgcagacgatcaagggctggatgctcgggccgagcttcgagggccgcaacgcg
acccaccagatgaagaagctcaccgtcgccgacctcaagggcttccgcgaccggctgcac
ctgccgatcccggacagcgagctggagtcgggcctgccgccctactaccacccggggcgc
gactccgaggagatccagtacatgcacgaccgccgccgtgaactcggcggctacgtgccc
acccgcgtcaaccgcgccaagccgctcccccagccgggggacaaggcgtacgccgccgtg
cggaagggctcgggccagcagcaggtcgccacgacgatggcgttcgtacggctgctcaag
gacctgatgcgggacaaggagatcggcaagcggttcgtgccgatcgcgccggacgagtac
cgcacgttcggcatggactcgctgttcccctcggcgaagatctacaacccgctggggcag
acctacgagtcggtggaccgggacctgctcctgtcgtacaaggagtcgccgaccgggcag
atgctgcacgacggcatcacggaggccggttgcaccgcgtcgctgatcgccgcgggctcg
gcgtacgcgacgcacggtgagcacctcatcccgatctacgtcttctactcgatgttcggg
ttccagcgcaccggtgaccagttctggcagatgggcgaccagctcgcgcgcggcttcgtg
ctcggcgccaccgcgggccgcacgacgctcaccggcgagggcacccagcacgccgacggg
cactcgcagctgctcgcctcgaccaacccggcctgcgtctcctacgacccggccttcggg
tacgagatcgcgcacatcgtgcgggacggcctgcggcgcatgtacggcgagaacgccgag
gacgtcttctactacctcaccgtctacaacgagccgatcaaccagccggccgagccggag
aacgtcgacgtcgagggcatcctcaagggcctgtaccgctaccgcgagggcacgggcacg
gggaccagggcgcagatcctggcctccggcgtcgccgtgccgtgggccgtggaggcccag
cgcatcctcgcggaggagtggcaggtcacggcggacgtgtggtcggcgacctcgtggaac
gagctgcgccgtgacgccgtcgaggccgaggagcacaacctgctgcaccccgaggaggag
cagcgcgtgccctacgtgacgcgcaagctccagggcgccgagggaccggtcgtggccgtg
tccgactggatgcggtcggttcccgaccagatcgcccgctgggtaccgggcacttaccag
tcgctcggcggcgacggcttcggcttcgccgacaccaggggcgcggcgcgccgcttcttc
cacatcgacgcccagtcgatcgtcctcggcgtgctcaccgagctggccaaggaagggaag
atcgaccgctcggtcctcaagcaggccatcgaccgctaccagctgctcgacgtggcggcg
gccgacccgggccccgcgggcggcgacgcgtaa
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