Serratia marcescens SM39: SM39_3945
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Entry
SM39_3945 CDS
T03592
Symbol
metH
Name
(GenBank) homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
smar
Serratia marcescens SM39
Pathway
smar00270
Cysteine and methionine metabolism
smar00450
Selenocompound metabolism
smar00670
One carbon pool by folate
smar01100
Metabolic pathways
smar01110
Biosynthesis of secondary metabolites
smar01230
Biosynthesis of amino acids
Module
smar_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
smar00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SM39_3945 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SM39_3945 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SM39_3945 (metH)
09150 Organismal Systems
09154 Digestive system
04980 Cobalamin transport and metabolism
SM39_3945 (metH)
Enzymes [BR:
smar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SM39_3945 (metH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BAO35884
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Position
complement(4088042..4091743)
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AA seq
1233 aa
AA seq
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MAMEGVTVTNRVEQLRRQLAQRILVLDGGMGTMIQSYRLDERDFRGERFADWRSDLKGNN
DLLVLTKPEVIAAIHYAYLEAGADILETNTFNATSIAMADYHMESLSAEINYQAACLART
CADEWTARTPEKPRYVAGVLGPTNRTASISPNVNDPAFRNISFDELVTAYRESTRALVEG
GVDLIMIETIFDTLNAKAAAFAVETEFEALGVELPIMISGTITDASGRTLSGQTTEAFYN
SLRHVKPLTFGLNCALGPDELRQYVAELARISETYVTAHPNAGLPNAFGEYDLDAAEMAR
QVGEWAQAGFLNIIGGCCGTTPEHIAAMAKAVEGVPPRRLPEIPVACRLAGLEPLTIDAN
TLFVNVGERTNVTGSARFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAM
VRFLNLIAGEPDIARVPIMIDSSKWSVIEKGLKCIQGKGIVNSISMKEGEEAFIHHAKLV
RRYGAAVVVMAFDEVGQADTRERKFEICRRAYNILTERVGFPPEDIIFDPNIFAVATGIE
EHNNYAVDFIEACADIKTHLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYHAIRNGMD
MGIVNAGQLAIYDDLSAELRDAVEDVILNRREDGTERLLELAEKYRGSKDNDVAVQQAEW
RGWPVEKRLEYSLVKGITEFIELDTEEARQQAERPIEVIEGPLMAGMNVVGDLFGEGKMF
LPQVVKSARVMKQAVAYLEPYIEASKQQGTSAGKILLATVKGDVHDIGKNIVGVVLQCNN
YEIVDLGVMVPTEKILRTAREENVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGG
ATTSKAHTAVKIEQNYSGPTTYVQNASRTVGVVSALLSATQRDEFVARTRKEYETVRIQH
ARKKPRTPPVDLQKARANAMALDWADYQPPVPRQLGVFPVAAGIETLRHYIDWTPFFMTW
SLAGKYPRILEDEVVGEEAKRLFHDANQMLDRLAAERSLNPRGVYGLFPANRVGDDVEVY
RDERRDEVLAVSRHLRQQTEKTDFPNYCLADFVAPKSSGKADYFGAFAVTGGLEEDALAA
AYDAQHDDYNKIMVKALADRLAEAFAEYLHEQVRKLHWGYAADESLSNEELIRENYQGIR
PAPGYPACPEHTEKATIWQLLDVNRHTGMELTESFAMWPGAAVSGWYFSHPESKYFAVAQ
IQRDQVEDYAARKGMSVSEVERWLAPNLGYDAD
NT seq
3702 nt
NT seq
+upstream
nt +downstream
nt
atggcaatggaaggggttacagtgacgaatcgagtagaacaactgcgccgccagttagcg
cagcgcattttggtgttggacggcggcatgggcaccatgatccagagctatcgtctggat
gagcgcgatttccgcggtgagcgtttcgccgactggcgcagcgatctgaaaggcaataac
gatctgctggtgctgaccaagccggaagtgatcgccgccattcattacgcctatctcgag
gcgggcgccgatatccttgaaaccaataccttcaacgccacctccatcgccatggccgac
taccacatggagtcgctgtccgccgagattaactatcaggccgcctgcctggcgcgcacc
tgcgccgacgaatggacggcgcgcacgccggaaaaaccgcgctacgtcgccggggtgttg
gggccgaccaaccgcactgcgtccatctcgccgaacgtcaacgatccggcgttccgcaac
atttcgttcgacgagctggtgacggcttaccgtgaatcgactcgtgcgctggtggagggc
ggcgtcgatctgatcatgatcgaaaccatcttcgacaccctgaatgccaaggccgccgcc
tttgcggtggaaaccgaattcgaagcgctgggggtggaactgccgatcatgatttccggc
accatcaccgacgcttccggccgcactttgtccggccagaccaccgaggcgttttacaat
tcgctgcgccacgtcaagccgctgaccttcggcctgaactgcgctctgggcccggacgaa
ctgcgtcagtacgtcgccgagctggcgcgcatctcggagacctacgtcaccgcgcacccg
aacgccggtttgccgaacgccttcggcgagtacgatctggatgcggccgagatggcgcgc
caggtcggggagtgggcgcaggccggcttcctcaatatcatcggcggctgctgcggcacc
acgccggaacatatcgccgcgatggccaaggcggtcgagggcgtgccgccgcgccggctg
ccggagatcccggtcgcctgccgcctggcgggcctggagccgctgaccatcgatgccaac
accctgttcgtcaacgtcggcgagcgcaccaacgtcaccggttcggcacgattcaaacgg
ttgatcaaagaagagaaatacaacgaggcgctcgacgtggcgcgccagcaggtcgagagc
ggcgcgcagatcatcgacatcaacatggacgaggggatgctcgacgccgaagcggcgatg
gtgcgcttcctcaacctgatcgccggcgagccggatatcgcccgggtgccgatcatgatc
gactcctccaagtggtccgttatcgagaaaggcctgaaatgcatccagggcaagggaatc
gtcaactcgatctcgatgaaggagggcgaagaggcctttatccatcacgccaaactggtg
cgccgttatggcgccgcggtggtggtgatggcgttcgacgaagtggggcaggctgacacc
cgcgagcgcaagttcgagatctgccgccgcgcctataacattctgaccgagcgcgtcggc
ttcccgccggaagacatcattttcgacccgaacattttcgccgtcgctaccggtatcgaa
gagcacaacaactacgccgtcgactttatcgaagcctgtgccgacatcaaaacccacctg
ccgcacgcgatgatctccggcggcgtgtccaacgtgtcgttctcgttccgcggcaacgat
ccggtgcgtgaagcgatccacgcggtgttcctgtatcacgccattcgcaacggcatggac
atgggcatcgtcaacgccgggcaactggcgatttatgacgatttaagcgccgagctgcgc
gacgcggtggaggacgtgatcctcaaccgtcgcgaggacggcaccgaacgcctgctggag
ctggcggaaaagtaccgtggcagcaaagataatgacgtggcggtgcagcaggcggagtgg
cgcggctggccggtggagaaacggctggagtattcgctggtgaagggcatcaccgaattt
atcgagctggacaccgaagaagcgcggcagcaggccgaacgcccgatcgaagtgatcgaa
gggccgctgatggcggggatgaacgtggtcggcgatctgttcggcgagggcaagatgttc
ctgccgcaggtggtgaaatccgcccgcgtgatgaagcaggcggtggcctacctggaaccc
tacatcgaggccagcaagcagcagggcacctccgcgggcaaaatcctgttggcgacggtg
aagggcgacgtgcacgacatcggcaagaacatcgtcggcgtggtattgcagtgtaacaac
tatgaaatcgtcgatctgggcgtgatggtgccgacggagaaaatcctgcgcaccgcgcgc
gaggagaacgtggatatcatcggcctgtcgggcctgatcacgccatcgctggacgagatg
gtcaacgtggccaaagagatggagcgccagggctttacgttgccgctgctgatcggcggc
gccaccacctccaaggcgcacaccgcggtgaagatcgagcagaactacagcggcccgacc
acctacgtgcagaatgcttcgcgcaccgtgggcgtggtgtcggcgctgctgtccgccacc
cagcgcgacgagtttgtggcgcgtacccgcaaagagtatgaaacggtgcgcattcagcac
gcgcgcaaaaagccgcgcacgccgccggtcgatctgcagaaggcgcgcgccaacgccatg
gcgctggactgggccgattatcagccgcctgtgccgcggcagctcggcgtgttcccggtg
gcggccggcatcgagacgctgcgccactacatcgactggacgccgttcttcatgacctgg
tcgctggcgggcaaatacccgcgcatcctggaagacgaggtggtgggggaagaggccaaa
cgcctgttccacgacgccaatcagatgctggatcggctggccgccgagcgcagcctcaac
ccgcgcggcgtttacggtctgttcccggccaaccgcgtcggagatgacgtggaggtgtac
cgcgacgaacggcgtgacgaggtgctggcggtgagccgccatctgcgccagcagacggaa
aaaaccgacttcccgaactactgcctggcggactttgtggcgccgaaaagcagcggcaag
gccgactacttcggcgccttcgcggtgaccggcgggctggaggaggacgcgctggcggcg
gcgtacgacgcgcagcacgacgattacaacaaaatcatggtcaaggcgctggcggatcgc
ctggcggaggccttcgccgaatacctgcatgagcaggtgcgcaagctgcactggggctat
gccgccgacgagagcctgagcaacgaagagctgatccgcgaaaactatcagggcatccgg
ccggcgccgggctacccggcctgcccggaacacaccgagaaagcgaccatttggcagctg
ctggacgtcaaccgccacaccggcatggagctgacggagtccttcgccatgtggccgggg
gcggcggtgtccggctggtacttcagccatcctgaaagcaagtacttcgcggtggcgcag
atccagcgcgatcaggtggaagactacgcggcgcgtaaagggatgagcgtgagcgaggtc
gaacgctggctggcgcctaacctcggctacgacgccgactga
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