Scophthalmus maximus (turbot): 118283187
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Entry
118283187 CDS
T09850
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
smau
Scophthalmus maximus (turbot)
Pathway
smau00140
Steroid hormone biosynthesis
smau01100
Metabolic pathways
Module
smau_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
smau_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
smau_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
smau00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
118283187 (hsd3b1)
Enzymes [BR:
smau01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
118283187 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
118283187 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
KR
NmrA
adh_short
Motif
Other DBs
NCBI-GeneID:
118283187
NCBI-ProteinID:
XP_035460816
UniProt:
A0A2U9CCN8
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Position
14:3376245..3380134
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AA seq
374 aa
AA seq
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MSLRGEVCLVTGAGGFLGKRLVRLLLEEEKTAEIRLLDKRVQPDLLQTLEGCRGDTKLSV
FEGDIRDGDFVRDACRGASVVFHIAAIIDVNESVEYSEIYGVNVKGTQVLLEACLQENIA
SFIYTSTIEVMGPNPRGEPLVNGSEDTVYDCSLKFSYSKTKKEAEQRTLLAHGEALRNGG
RLATCALRPMYIFGEGCSFLLRHMGDGIRNRDVLLRMSLPEARVNPVYVGNVAAAHLQAA
RGLKDPQKRNAMGGKFYFIADDTPPVSYSDFNHVVLSPLGFGIQEKLPLPLGLLYALCFV
LEMLCLMLRPLLRVTPPLNRQLVTMLNTPFTFSYQRAKRDLGYEPRYSWEEARKNTTEWL
ASQLPKERERIRAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgagaggtgaagtgtgcctggtgacgggggccggcggcttcctggggaagagg
ctggtgcggctgctgctggaggaggagaagacggccgagattcggctgctggacaaacgc
gtacagccggacctcctgcaaacgctggagggctgccgaggcgacaccaagctgagtgtt
ttcgagggcgacatccgggacggagacttcgtgagagacgcctgtcgcggggcgtcggtc
gtcttccacatcgcggccatcatcgacgtcaatgagtcggtggagtacagtgaaatctac
ggggtcaatgtcaaagggacgcaggtgctcctggaggcgtgtctccaggagaacatcgcg
tccttcatctacaccagcaccatcgaggtgatgggaccgaacccccggggcgagcccctg
gtcaacggcagcgaggacacggtgtacgactgctccctcaagttttcctacagcaagacc
aagaaggaggcggagcagagaaccctgctggcccacggcgaggcgctccggaacggcggc
cgcctggccacctgcgccctcaggcccatgtacatcttcggggagggctgcagcttcctg
ctgaggcacatgggcgacgggatccggaaccgggacgttctgttgcggatgtccctaccg
gaggcccgcgtgaaccccgtctatgtgggcaacgtggccgcggcccacctgcaggcggcc
cgcggcctcaaggacccgcagaagaggaacgcgatgggggggaagttctacttcatcgcc
gacgacacgccgcccgtgagctactcggacttcaaccacgtcgtgctgtcgcctctgggc
ttcggcattcaggagaagctcccgctgccgctcggcctcctctacgcgctctgcttcgtg
ctggagatgctgtgcctgatgctgcggccgctgctccgcgtcaccccgccgctgaaccgg
cagctcgtcaccatgctgaacacgccgttcaccttctcctaccagagggccaagcgggac
ctgggatacgaaccccgatacagctgggaggaggcgcgcaagaacaccaccgagtggctc
gcgtcgcagctgccgaaggagcgggagcgaatcagagctaaatga
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