KEGG   Streptomyces mirabilis: SMIR_10125
Entry
SMIR_10125        CDS       T10322                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
smib  Streptomyces mirabilis
Pathway
smib03030  DNA replication
smib03410  Base excision repair
smib03420  Nucleotide excision repair
smib03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:smib00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    SMIR_10125 (ligA)
   03410 Base excision repair
    SMIR_10125 (ligA)
   03420 Nucleotide excision repair
    SMIR_10125 (ligA)
   03430 Mismatch repair
    SMIR_10125 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:smib03032]
    SMIR_10125 (ligA)
   03400 DNA repair and recombination proteins [BR:smib03400]
    SMIR_10125 (ligA)
Enzymes [BR:smib01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     SMIR_10125 (ligA)
DNA replication proteins [BR:smib03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     SMIR_10125 (ligA)
DNA repair and recombination proteins [BR:smib03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     SMIR_10125 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     SMIR_10125 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     SMIR_10125 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      SMIR_10125 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT Nlig-Ia HHH_5 HHH
Other DBs
NCBI-ProteinID: QUW79431
LinkDB
Position
complement(2349829..2352024)
AA seq 731 aa
MAGDKDAQPNSLPAEAREQHAQLAEQIEEHRFRYYVKDQPVVSDAEFDQLLRSLEALEER
YPELRTPDSPTQKVAGAYATEFTSVQHRSRMLSLDNAFSDLELAAWAERVAKDVGTSDHH
FLCELKVDGLAVNLTYEHGRLTRAATRGDGRTGEDITPNVRTIAEIPDRLKGDHVPDLVE
IRGEVYFPMEKFEELNARLVEAGDKLFANPRNAAAGSLRQKDPRVTASRPLHMVVHGIGA
LEGFEGLTRLSEAYTLLHSWGLPTTRYAKVVDDLDGVREFIAYYGENRHSVEHEIDGVVV
KLDEIRLQGRLGSTARAPRWAIAWKYAPEEVNTKLVDIKVGVGRTGRVTPYAQVEPVTVA
GSEVEFATLHNQEVVKAKGVLIGDTVVLRKAGDVIPEILGPVVDLRDGTEREFVMPAECP
ECGTPLRAMKEGDIDLRCPNGRTCPAQLRERVSYLAGRECLDIEHFGNVAAAALTRPLEP
AAPPLVDEGDLFDLTVEQLLPIKAYVLDQDSGLPKRDPKTGEEKVVTVFANQKGEPKKNT
LALLDNIAEAKSRPLARFINGLSIRHVGPVAAEALAREFRSIDRIEQATEEELAAVDGVA
GIIATSVKQWFTEDWHREIIRKWKAAGVRLEDEGSGEDEGPRPLEGLTVVVTGTLEHHTR
DGAKEALQSRGGKVTGSVSKKTSFVVVGDNPGSKYDKAMQLKVPVLNEEGFAVLLEQGPE
AAAEVALPTGE
NT seq 2196 nt   +upstreamnt  +downstreamnt
gtggccggcgacaaggacgcacagcccaattccctgcccgccgaggcacgggagcagcac
gcccagctcgctgagcagatcgaggagcaccgcttccggtactacgtgaaggaccagccg
gtcgtcagcgacgcggagttcgaccagttgctgcgctcgctggaggccctggaggagcgg
tatcccgagctgcgcacccccgactccccgacccagaaggtcgcgggcgcgtacgcgacc
gagttcacctccgtccagcaccgctcgcgcatgctctcgctggacaacgctttcagcgac
ctggagctcgcggcctgggccgagcgcgtcgccaaggacgtgggcacctcggaccaccac
ttcctgtgcgagctgaaggtcgacggcctcgcggtcaacctgacctacgagcacggccgc
ctcacccgcgcggcgacccgcggcgacggccgcacgggcgaggacatcacgcccaatgtg
cgcacgatcgcggagattccggaccgcctcaagggcgaccacgtcccggacctggtggag
atccgcggcgaggtctacttcccgatggagaagttcgaggagctcaacgcccgcctggtg
gaggccggcgacaagctcttcgccaacccgcgcaacgcggcggcgggttcgctgcggcag
aaggacccccgcgtcaccgcgagccgccccctgcacatggtggtccacggaatcggcgcc
ctggagggcttcgagggcctcacccggctctccgaggcgtacacactgctgcactcctgg
ggcctgccgaccacgcggtacgcgaaggtggtcgacgacctcgacggcgtacgggagttc
atcgcgtactacggcgagaaccggcactccgtggagcacgagatcgacggagtcgtcgtc
aagctcgacgagatccgtctccagggccgcctcggttccacggcccgcgctccacgctgg
gccatcgcctggaagtacgcgccggaagaggtcaacaccaagctggtcgacatcaaggtc
ggcgtcggccgaacagggcgcgtcactccgtacgcgcaggtcgagccggtcaccgtggcg
ggctcagaggtcgagttcgcgactctgcacaaccaggaggtcgtgaaggccaagggcgtc
ctcatcggggacacggtcgtgctgcgtaaggccggtgacgtcatcccggagatcctcgga
ccggtggtggatctccgcgacggcaccgagcgggagttcgtgatgccggccgagtgcccc
gagtgcgggacgccgctgcgcgccatgaaggaaggcgacatcgacctgcgctgccccaac
ggccgtacctgcccggcccagttgagagagcgcgtctcctacctcgcgggccgggagtgc
ctcgacatcgagcacttcggcaatgtggccgcggcggcgctgacccgtccgctggagccc
gccgccccaccgctcgtcgacgagggcgacctcttcgacctcacggtcgagcagctgctc
ccgatcaaggcgtacgtcctcgaccaggacagcggcctgcccaagcgggaccccaagacc
ggtgaggagaaggtcgtcacggtcttcgccaaccagaagggcgagccgaagaagaacacg
ctcgctctgctcgacaacatcgccgaggcgaagagccgcccgctcgcgcgcttcatcaac
ggactctccatcagacacgtcggcccggtggccgccgaggcgctggcccgcgagttccgt
tccatcgaccgcatcgagcaggccaccgaggaggaactcgccgcggtcgacggggtcgcc
gggatcatcgcgacctcggtcaagcagtggttcacggaggactggcaccgcgagatcatc
cgcaaatggaaggccgccggcgtccggttggaggacgagggttccggcgaggacgagggc
ccgcggcccctcgaaggactcaccgtcgtcgtcaccggcacgctcgaacaccacacgcgg
gacggcgcgaaggaggcccttcagagccggggagggaaggtgaccggttcggtctcgaag
aagacgtctttcgtggtcgtgggcgacaatccaggatctaagtacgacaaggcgatgcag
ctgaaggtgccggttctgaacgaggagggcttcgccgtcctgctcgaacagggaccggag
gccgccgcggaagtcgccctcccgaccggggagtag

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