Streptomyces mirabilis: SMIR_11350
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Entry
SMIR_11350 CDS
T10322
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
smib Streptomyces mirabilis
Pathway
smib00020
Citrate cycle (TCA cycle)
smib00630
Glyoxylate and dicarboxylate metabolism
smib00785
Lipoic acid metabolism
smib01100
Metabolic pathways
smib01110
Biosynthesis of secondary metabolites
smib01120
Microbial metabolism in diverse environments
smib01200
Carbon metabolism
smib01210
2-Oxocarboxylic acid metabolism
Module
smib_M00009
Citrate cycle (TCA cycle, Krebs cycle)
smib_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
smib00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SMIR_11350
00630 Glyoxylate and dicarboxylate metabolism
SMIR_11350
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SMIR_11350
Enzymes [BR:
smib01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SMIR_11350
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SMIR_11350
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SMIR_11350
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SMIR_11350
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SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QUW79638
LinkDB
All DBs
Position
2620140..2623976
Genome browser
AA seq
1278 aa
AA seq
DB search
MSPQSPSNSSISTDDQAAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAPAASASAGTAAAGAAGTTTPSAAPQAAPAAPAAPAAPSAPAAPAQAAPAAPAPAQAAA
PAAAPVAPKPAAAAPAPVKAAPAAAKPKAEPATEAPAGPEYVTLRGPAGAVAKNMNASLE
LPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWHYAE
KDGKPTLVKPPHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDG
KLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLG
ISKVMTLTSTYDHRVIQGAASGEFLRIVANLLLGENGFFDEIFEALRIPYEPVRWLKDID
ASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFA
VGGFSGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHSKPEREEQL
RILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHR
GRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAQGTFTGLDGEQIKVSLAA
NPSHLETVDPVIEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRG
YRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAF
EFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDIT
LEEAEQALQDFQGQLEKVFTEVREAVSQGAEVQISDPQAQFPVAVQTAVSQEVVKRIAES
QVNIPDNVTVHPRLLPQLQRRAAMIEDGTIDWGMGETLAIGSLLLEGTPVRLSGQDSRRG
TFGQRHAVLIDRVTGEDFTPLQYLSDDQARYNVYDSLLSEYAVMGFEYGYSLARPDALVM
WEAQFGDFVNGAQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLC
AQNNMTVAQPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTTGAFRP
VIGDDSVEASAVRKVVFCAGKLYYDLEAERQKRGVTDTAIIRIERLYPLAGAELQAEIAK
YPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADIPGAERLRRISRPAGSSPAVGS
AKRHQAEQEQLVREVFEA
NT seq
3837 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgatgaccaagccgccgggaag
aaccccgcggccgcgttcggtgcgaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggggcccctgccgcctcggcttcggcgggtactgcggccgcgggggccgcagggaccacc
accccgtcagcagcgcctcaggccgcgcctgccgctccggcagcccctgccgcgccctcg
gcgcccgcggccccggcccaggccgctcctgcggctcctgcgcccgcccaggccgccgct
cccgcggccgctccggtggctccgaagcccgctgccgccgccccggctcccgtgaaggcc
gctccggccgccgcgaagccgaaggccgagcccgcgaccgaggcccccgcgggtcccgag
tacgtgacgctgcgtggccccgccggtgccgtcgcgaagaacatgaacgcctccctggag
ctgcccacggccacgtccgtgcgcgcggtcccggtgaagctgctcttcgacaaccgcatc
gtcatcaacaaccacctgaagcgcgcccggggcgggaagatctccttcacccacctcatc
ggctacgcgatggtgcaggccatcaaggccatgccgtcgatgaactggcactacgcggag
aaggacgggaagccgaccctcgtcaagcctccgcacgtcaacttcggcctcgccatcgac
ctggtgaagccgaacggcgaccgccagctcgtcgtcgccggcatcaagaaggccgagacg
ctgaacttcttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggc
aagctgacgatggacgacttcacgggtgtcacggtctccctgacgaaccccggcggcctc
ggcaccgtccactccgtcccccgcctgatgcccggccagtcggtcatcatgggcgtcggc
tccatggactacccggcggagttccagggcacctcccaggacaccctgaacaagctcggc
atctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtgatccagggcgccgcc
tccggcgagttcctccgcatcgtcgcgaacctcctcctcggcgagaacggcttcttcgac
gagatcttcgaggccctgcgcatcccctacgagccggtccgctggctcaaggacatcgac
gccagccacgacgacgacgtcacgaaggccgcccgcgtcttcgagctgatccactcctac
cgggtccgcggccacgtcatggccgacaccgacccgctggagtaccgccagcgcaagcac
cccgacctcgacatcaccgagcacggcctcaccctgtgggacctggagcgcgagttcgcg
gtcggcggcttctccggcaagtcgatgatgaagctgcgcgacatcctcggcgtgctgcgc
gactcgtactgccgcaccaccggcatcgagttcatgcacatccaggacccgaagcagcgc
aagtggatccaggaccgcgtcgagcgcccgcactccaagccggagcgcgaggagcagctg
cgcatcctgcgccgcctgaacgcggcggaggccttcgagaccttcctgcagacgaagtac
gtcggccagaagcgcttctccctggagggcggcgagtccgtcatcccgctcctcgacgcc
gtcatcgacagcgccgcggagtcccgcctggacgaggtcgtcatcggcatggcccaccgc
ggccgcctgaacgtcctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgcgag
ttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctg
ggcgcccagggcaccttcaccggcctggacggcgagcagatcaaggtctcgctggccgcc
aacccctcccacctggagacggtcgacccggtcatcgagggcatcgcccgcgccaagcag
gacatcatcaacaagggcggcacggacttcaccgtcctgccggtcgccctgcacggtgac
gcggccttcgcgggccagggtgtggtcgccgagacgctgaacatgtcgcagctgcgcggc
taccgcaccggcggcacggtccacatcgtcatcaacaaccaggtcggcttcaccgccgcc
ccggagtcctcgcgctcctccatgtacgccaccgacgtggcccgcatgatcgaggcgccg
atcttccacgtgaacggcgacgaccccgaggccgtcgtccgcgtcgctcgtctggccttc
gagttccgccaggcgttcaacaaggacgtcgtgatcgacctcatctgctaccgccgtcgc
gggcacaacgagtcggacaacccggcgttcacgcagccgctgatgtacgacctgatcgac
aagaagcgctcggtgcgcaagctctacaccgagtccctgatcggccgcggcgacatcacc
ctcgaagaggccgagcaggcgctgcaggacttccagggccagctggagaaggtcttcacc
gaggtccgcgaggccgtctcgcagggggccgaggtgcagatctcggacccgcaggcgcag
ttcccggtggccgtgcagaccgcggtctcccaggaggtcgtgaagcggatcgccgagtcc
caggtcaacatccccgacaacgtcaccgtccacccgcgtctgctgccgcagctgcagcgc
cgggcggcgatgatcgaggacggcacgatcgactggggcatgggcgagaccctcgccatc
ggctccctcctcctggagggcaccccggtccggctgtcgggtcaggactcccgccgcggc
accttcggccagcgccacgcggtcctgatcgaccgggtcacgggcgaggacttcaccccg
ctccagtacctctccgacgaccaggcccgctacaacgtctacgactccctgctctccgag
tacgcggtcatgggcttcgagtacggctactcgctggcccgcccggacgccctcgtgatg
tgggaggcgcagttcggcgacttcgtcaacggcgcgcagacggtcgtcgacgaatacatc
tcggccgcggagcagaagtggggccagacgtccggcgtcacgctcctcctcccccacggc
tacgagggccagggcccggaccactcctcggcccgcatcgagcgcttcctccagctgtgc
gcgcagaacaacatgacggtcgcccagccgacgctcccgtcgaactacttccacctcctg
cggtggcaggtgcacaacccgcaccacaagccgctggtggtcttcaccccgaagtcgatg
ctgcgcctcaaggccgccgcgtcgaagacggaggagttcaccacgggcgccttccgcccc
gtcatcggcgacgactcggtcgaagcctcggcggtccgcaaggtcgtcttctgcgccggc
aagctgtactacgacctcgaggccgagcgtcagaagcgcggtgtcacggacacggcgatc
atccgcatcgagcgcctgtacccgctcgcgggtgccgagctccaggcggagatcgccaag
tacccgaacgccgagaagtacctgtgggcccaggaggagccggcgaaccagggcgcgtgg
cccttcatcgcgctcaacctgatcgaccacctggacctggccgtcggcgccgacatcccg
ggtgccgagcggctgcgccgcatctcccgcccggccggctcgtccccggccgtgggctcc
gcgaagcggcaccaggccgagcaggagcagctggtgcgtgaggtgttcgaggcgtag
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