Streptomyces moderatus: POD33_03880
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Entry
POD33_03880 CDS
T10886
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
smod Streptomyces moderatus
Pathway
smod00010
Glycolysis / Gluconeogenesis
smod00020
Citrate cycle (TCA cycle)
smod00620
Pyruvate metabolism
smod00785
Lipoic acid metabolism
smod01100
Metabolic pathways
smod01110
Biosynthesis of secondary metabolites
smod01120
Microbial metabolism in diverse environments
smod01200
Carbon metabolism
smod01210
2-Oxocarboxylic acid metabolism
Module
smod_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
smod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
POD33_03880 (aceE)
00020 Citrate cycle (TCA cycle)
POD33_03880 (aceE)
00620 Pyruvate metabolism
POD33_03880 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
POD33_03880 (aceE)
Enzymes [BR:
smod01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
POD33_03880 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
WCH91324
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Position
860805..863552
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATRDEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAFLLDRLSEQNLDAFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKVIQELESIFRGA
GWNVIKLIWDRTWDPLLAQDRDGLLVNRMNTTPDGQFQTYATETGAYIRDHFFGDDQRLR
TMVEGMTDDQILHLGRGGHDHKKIFAAFSAAKAHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPIADKDLDSGPPPYYHPGRDSEEIQYMHDRRKGLGGYVP
TRVVRSQPLALPDDKTYATVKKGSGHQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKESPQGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMSDQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAYSYEIAHIVKDGLRRMYGGDAEHPHGEDVFYYLTVYNEPIQH
PAEPENVDVEGILKGVHRLSAGTAGSIPAQIMASGVAVPWAVEAQKILAEEWNVKADVWS
ATSWNELRREAVECEEHNLLHPEEEQRVPYVTRKLSGAEGPFVAVSDWMRSVPDQIARWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSIVVGVLTELAKEGKVDRSALKQAIDRYQL
LDVSAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatcagatcgcaacccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaggaaacccaggagtggctcgattcgctcgacgccgccgtggacgag
cgcggccgggagcgggcccgctatctgatgctgcggctgatcgagcgggcgcgtgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacacgatcgcgaccagggac
gagccgttcttcccgggcaacgaggagatcgagcgcaagatcctcaacgccacccggtgg
aacgccgcggtgatggtgtccagggcgcagcgccccggcatcggcgtcggcggtcacatc
gccaccttcgcctcctccgcctccctctacgacgtgggcttcaaccacttcttccggggc
aaggacgagggcgacggcggcgaccaggtcttcttccagggccacgcctccccgggcatc
tacgcgcgcgcattcctgctggaccgcctcagcgagcagaacctcgacgcgttccgccag
gagaagtcgaaggcgccgtacggcctgtcctcctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtgtcgatgggcctcggcccgatcggcgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgcggacacctccaagtcgcacgtgtgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcggccagctgtccatcgcc
gcccgtgagggcctggacaacctgaccttcgtggtgaactgcaacctccagcgcctcgac
ggccccgtgcggggcaacggcaaggtcatccaggagctggagtcgatcttccgcggcgcc
ggctggaacgtgatcaagctcatctgggaccgcacctgggacccgctgctcgcccaggac
cgcgacggcctgctggtcaaccgcatgaacaccacgccggacggccagttccagacgtac
gccaccgagacgggcgcgtacatccgcgaccacttcttcggcgacgaccagcggctgcgc
acgatggtcgagggcatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
cacaagaagatcttcgcggccttctcggcggccaaggcgcacaagggccagccgacggtg
atcctcgccaagacgatcaagggctggacgctcggccccaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccggctgcac
ctgccgatcgccgacaaggacctggacagcggaccgccgccgtactaccacccggggcgc
gactccgaggagatccagtacatgcacgaccgccgcaaggggctcggcggttacgtcccg
acgcgtgtggtgcgctcccagccgctggcactgccggacgacaagacgtacgcgaccgtg
aagaagggctcgggtcaccagtccatcgcgacgaccatggccttcgtccggctcctcaag
gaccttatgcgggacaaggagatcggcaagcggttcgtactgatcgcgccggacgagtac
cgcacattcggcatggactccttcttcccgagtgcgaagatctacaacccgctcggccag
cagtacgagtcggtcgaccgcgatctgctgctcgcgtacaaggagtcgccgcagggccag
atgctgcacgacggcatctcggaggccggttgcacggcctcgctgatcgcggcgggctcg
gcgtacgccacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggt
ttccagcgcaccggcgaccagttctggcagatgtcggaccagctggcgcgcggtttcgta
ctgggcgcgaccgccggccgtacgaccctgaccggtgagggcctccagcacgcggacggc
cactcccagctgctcgcctcgaccaacccgggctgcgtcgcctacgacccggcctactcg
tacgagatcgcgcacatcgtcaaggacggtctgcgcaggatgtacggcggcgacgccgag
cacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagcccatccagcac
ccggccgagccggagaacgtcgacgtcgagggcatcctcaagggcgtccaccggctgagc
gcgggcaccgcggggtcgatcccggcgcagatcatggcctcgggtgtcgccgtcccgtgg
gcggtcgaggcgcagaagatcctcgccgaggagtggaacgtcaaggccgacgtctggtcg
gcgacgtcctggaacgagctgcggcgcgaggccgtggagtgcgaggagcacaacctgctg
catcccgaggaggagcagcgggtgccgtacgtgacccggaagctgagcggggccgaggga
ccgttcgtggccgtctccgactggatgcggtcggttccggaccagatcgcgcgctgggtg
ccgggcacctaccagtcgctgggcgcggacggcttcggcttcgcggacacccgtggcgcg
gcccgccgcttcttccacatcgacgcccagtcgatcgtggtcggggtgctgaccgagctg
gccaaggagggcaaggtggaccggtcggcgctgaagcaggcgatcgaccgctaccagctg
ctcgatgtgtcggcggcggacccgggcgccgcaggaggcgacgcgtag
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