Streptomyces moderatus: POD33_19785
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Entry
POD33_19785 CDS
T10886
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
smod Streptomyces moderatus
Pathway
smod00020
Citrate cycle (TCA cycle)
smod00630
Glyoxylate and dicarboxylate metabolism
smod00785
Lipoic acid metabolism
smod01100
Metabolic pathways
smod01110
Biosynthesis of secondary metabolites
smod01120
Microbial metabolism in diverse environments
smod01200
Carbon metabolism
smod01210
2-Oxocarboxylic acid metabolism
Module
smod_M00009
Citrate cycle (TCA cycle, Krebs cycle)
smod_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
smod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
POD33_19785
00630 Glyoxylate and dicarboxylate metabolism
POD33_19785
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
POD33_19785
Enzymes [BR:
smod01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
POD33_19785
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
POD33_19785
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
POD33_19785
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
POD33_19785
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WCH94246
LinkDB
All DBs
Position
complement(4333236..4337036)
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AA seq
1266 aa
AA seq
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MSPQSPSNSSISTDTDQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAGAAAPAGTAAAGAADTTTAPKPAPAAPAAPAAPSVPAPAPAAAQPAPAAQAPAAAPAK
PAAPAPAAKPAQQKKAEPAAASAEGPELVTLRGPAAAVAKNMNASLEVPTATSVRAVPVK
LLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTLVKPEHI
NFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLGMDDFTGVTVS
LTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDH
RVIQGAASGEFLRIVANFLLGEGNFYDEIFEALRIPYEPVRWLKDIDASHDDDVTKAARV
FELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSLMKLR
DILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERPHTKPEREEQLRILRRLNAAEAFE
TFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANIVGKS
YAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQINVSLAANPSHLETVDPVIE
GIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINN
QVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVID
LICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQG
QLEKVFTEVREAVTAQPAAGPVSDPQAEFPVAVSTAISSETVKRIAESQVNIPDTFHVHP
RLLPQLQRRATMVEDGTIDWGMGETLAVGSLLLEGTPVRLSGQDSQRGTFGQRHAVLIDR
ETGEEHTPLQYLAEEQARYNVYNSLLSEYAVMGFEYGYSLARPDALVMWEAQFGDFVNGA
QTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQNNMTVAMPTL
PSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTSGQFRPVIGDASVDPAAV
RKVVFVAGKLYYDLEAERVKRGITDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLWAQE
EPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQLV
REVFEA
NT seq
3801 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcgggcaag
aaccccgcggccgcgttcggtccgaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccc
ggcgccggcgccgcggcgccggcgggtactgcggccgcgggggccgcagacaccaccacg
gcccccaagcccgcgcccgccgccccggctgctccggccgcaccgtcggtgcccgcgccg
gcccccgcggccgcgcagcccgcgcccgccgcgcaggccccggccgccgctccggcgaag
cccgccgcgcccgctccggccgcgaagcccgctcagcagaagaaggccgagcccgccgcc
gcctcagccgagggccccgagctcgtcacgctgcgcggcccggccgccgcggtcgcgaag
aacatgaacgcctcgctggaggtgcccacggccacgtccgtgcgcgcggtcccggtgaag
ctgctgttcgacaaccgcatcgtcatcaacaaccacctgaagcgcgcccggggcgggaag
atctccttcacgcacctgatcggctacgcgatggtgcaggccatcaaggccatgccgtcg
atgaactactccttcgcggagaaggacggcaagccgaccctggtcaagccggagcacatc
aacttcggcctcgccatcgacctggtcaagcccaacggcgaccgccagctcgtggtcgcg
ggcatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatc
gtccggcgcgcccgcgacggcaagctcggcatggacgacttcaccggcgtcacggtctcc
ctgaccaaccccggcggcctcggcaccgtccactccgtcccgcgtctgatgcccggccag
tcggtcatcatgggcgtcggctccatggactacccggcggagttccagggcacctcccag
gacaccctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccac
cgggtcatccagggcgccgcgtccggcgagttcctgcggatcgtcgcgaacttcctgctc
ggcgagggcaacttctacgacgagatcttcgaggcgctgcgcatcccctacgagccggtc
cgctggctcaaggacatcgacgccagccacgacgacgacgtcacgaaggccgcccgcgtc
ttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctg
gagtaccgccagcgcaagcaccccgacctcgacatcaccgagcacggcctcaccctgtgg
gacctggagcgcgagttcgcggtcggcggcttctccggcaagtccctgatgaagctgcgc
gacatcctcggtgtcctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcac
atccaggacccgaagcagcgcaagtggatccaggaccgcatcgagcgcccgcacaccaag
ccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgccgcggaggccttcgag
accttcctgcagacgaagtacgtcggccagaagcgcttctccctggagggcggcgagtcc
gtcatcccgctgctcgacgcggtgctggactcggccgccgagtcccgcctggacgaggtc
gtcatcggcatggcccaccgcggccgcctgaacgtcctcgccaacatcgtcggcaagtcg
tacgcccagatcttccgtgagttcgagggcaacctcgacccgaagtcgatgcacggctcc
ggcgacgtgaagtaccacctgggcgccgagggcaccttcacgggcctggacggcgagcag
atcaacgtctcgctggccgcgaacccctcccacctggagacggtcgacccggtcatcgag
ggcatcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctg
cccgtcgccctgcacggcgacgcggccttcgcgggccagggcgtggtggcagagaccctg
aacatgtcgcagctgcggggctaccgcaccggcggcacggtccacatcgtcatcaacaac
caggtcggcttcacggcggcgcccgagtcctcgcgctcctccatgtacgccaccgacgtg
gcccgcatgatcgaggctccgatcttccacgtgaacggcgacgacccggaggccgtggtc
cgcgtcgcgcggctcgccttcgagttccgtcaggcgttcaacaaggacgtggtgatcgac
ctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccagccg
ctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctc
atcggtcgcggcgacatcaccctggaagaggccgagcaggcgctccaggactaccagggc
cagctggagaaggtcttcaccgaggtccgcgaggccgtcacggcccagccggccgccggt
cccgtctcggacccgcaggcggagttcccggtcgccgtgagcaccgcgatctcctcggag
accgtgaagcggatcgccgagtcccaggtcaacatccccgacaccttccacgtccacccg
cgtctgctgccgcagctccagcgccgggcgacgatggtcgaggacgggacgatcgactgg
ggcatgggcgagacgctggccgtcggctccctcctcctggagggcaccccggtccgcctc
tccggccaggactcccagcgcggcaccttcggccagcggcacgcggtcctcatcgaccgt
gagacgggcgaggagcacaccccgctccagtacctcgccgaggagcaggcgcgctacaac
gtctacaactccctgctctccgagtacgcggtcatgggcttcgagtacggctactcgctg
gcccgccccgacgcgctcgtgatgtgggaggcgcagttcggcgacttcgtcaacggcgcg
cagacggtggtcgacgagtacatctcggcggcggagcagaagtggggccagacgtccggc
gtcaccctgctgctcccccacggctacgagggccagggcccggaccactcctcggcccgt
gtcgagcgcttcctccagctgtgcgcccagaacaacatgacggtcgcgatgccgaccctg
ccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctg
gtggtcttcaccccgaagtcgatgctgcgcctcaaggccgccgcgtcgaagacggaggag
ttcacgtcgggtcagttccgcccggtcatcggcgacgcgtcggtggacccggccgcggtc
cgcaaggtcgtcttcgtcgcgggcaagctgtactacgacctggaggccgagcgggtcaag
cgcggcatcacggacacggcgatcatccggatcgagcggctgtacccgctccccggtgcg
gagctccaggccgagatcgccaagtacccgaacgccgagaagtacctgtgggcccaggag
gagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctggac
ctggcggtcggcgccgacgtcccgcacggcgagcgcctgcggcggatctcccgcccgcac
ggctcgtccccggcggtcggttcggccaagcgccaccaggcggagcaggagcagctggtg
cgcgaggtgttcgaggcgtaa
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