KEGG   Serratia marcescens WW4: SMWW4_v1c44580
Entry
SMWW4_v1c44580    CDS       T02448                                 
Symbol
metH
Name
(GenBank) homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
smw  Serratia marcescens WW4
Pathway
smw00270  Cysteine and methionine metabolism
smw00450  Selenocompound metabolism
smw00670  One carbon pool by folate
smw01100  Metabolic pathways
smw01110  Biosynthesis of secondary metabolites
smw01230  Biosynthesis of amino acids
smw04981  Folate transport and metabolism
Module
smw_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:smw00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    SMWW4_v1c44580 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    SMWW4_v1c44580 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SMWW4_v1c44580 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    SMWW4_v1c44580 (metH)
   04980 Cobalamin transport and metabolism
    SMWW4_v1c44580 (metH)
Enzymes [BR:smw01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     SMWW4_v1c44580 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AGE20245
LinkDB
Position
complement(4825868..4829563)
AA seq 1231 aa
MEGVTVTNRVEQLRRQLAQRILVLDGGMGTMIQSYRLDERDFRGERFADWRSDLKGNNDL
LVLTKPEVITAIHYAYLEAGADILETNTFNATSIAMADYHMESLSAEINYQAACLARACA
DEWTARTPEKPRYVAGVLGPTNRTASISPNVNDPAFRNISFDELVAAYRESTRALVEGGV
DLIMIETIFDTLNAKAAAFAVETEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSL
RHVKPLTFGLNCALGPDELRQYVAELARISETYVTAHPNAGLPNAFGEYDLDAAEMARQV
GEWAQAGFLNIIGGCCGTTPEHIAAMAKAVEGVPPRRLPELPVACRLAGLEPLTIDASTL
FVNVGERTNVTGSARFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMVR
FLNLIAGEPDIARVPIMIDSSKWSVIEKGLKCIQGKGIVNSISMKEGEEAFIHHARLVRR
YGAAVVVMAFDEVGQADTRERKFEICRRAYKILTERVGFPPEDIIFDPNIFAVATGIEEH
NNYAVDFIEACADIKTHLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYHAIRNGMDMG
IVNAGQLAIYDDLPGELREAVEDVILNRREDGTERLLELAEKYRGSKDGEAAVQQAEWRG
WPVEKRLEYSLVKGITEFIELDTEEARQQAERPIEVIEGPLMAGMNVVGDLFGEGKMFLP
QVVKSARVMKQAVAYLEPYIEASKQQGTSAGKILLATVKGDVHDIGKNIVGVVLQCNNYE
IVDLGVMVPTEKILRTAREENVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGAT
TSKAHTAVKIEQNYSGPTTYVQNASRTVGVVAALLSATQRDEFVARTRKEYETVRIQHAR
KKPRTPPVDLHKARANAMALDWADYQPPAPRQLGVFPVSAGIETLRHYIDWTPFFMTWSL
AGKYPRILEDEVVGEEAKRLFHDANQMLDRLAAERSLNPRGVYGLFPANRVGDDVEVYRD
EQRSEVLAVSRHLRQQTEKTDFPNYCLADFVAPKSSGKADYFGAFAVTGGLEEDALAAAY
DAQHDDYNKIMVKALADRLAEAFAEYLHEQVRKLHWGYAADENLSNEELIRENYQGIRPA
PGYPACPEHTEKATIWQLLDVNRHTGMELTESFAMWPGAAVSGWYFSHPESKYFAVAQIQ
RDQVEDYAARKGMSVSEVERWLAPNLGYDAD
NT seq 3696 nt   +upstreamnt  +downstreamnt
atggaaggggttacagtgacgaatcgagtagaacaactgcgccgccagttagcgcagcgc
attttggtgttggacggcggcatgggcaccatgatccagagctaccgtctggatgagcgc
gatttccgcggtgagcgtttcgccgactggcgcagcgatctgaaaggcaataacgatctg
ctggtgctgaccaagccggaagtgatcaccgccattcattacgcctatctcgaggcgggc
gctgatatccttgagaccaataccttcaacgccacctccatcgccatggccgactaccat
atggagtcgctgtccgccgagattaactatcaggccgcctgcctggcgcgcgcctgcgcc
gacgaatggacggcgcgcacgccggaaaaaccgcgctacgtcgccggggtgttggggccg
accaaccgcaccgcgtccatctcgccgaacgtcaacgatccggcgttccgcaacatctcg
ttcgatgaactggtggcggcttaccgcgaatcgacccgcgcgctggtggagggcggcgtc
gatctgatcatgatcgagaccatcttcgacaccctcaacgccaaggccgccgcttttgcg
gtggaaactgaattcgaagcgctgggagtggaactgccgatcatgatttccggcaccatc
accgacgcctccggccgcaccctgtccggccagaccaccgaagcgttttacaattcgctg
cgccacgtcaagccgctgaccttcggcctgaactgcgccctggggccggatgagctgcgt
cagtacgtcgccgagctggcgcgcatctcggagacctacgtcaccgcgcacccgaacgcc
ggtttgccgaacgccttcggcgagtacgatctggatgcggccgagatggcgcgccaggtt
ggggagtgggcgcaggccggcttcctcaatatcatcggcggctgctgcggcaccacgccg
gaacatatcgccgcgatggccaaggcggtcgagggcgtgccgccgcgccggctgccggag
ctcccggtcgcctgccgcctggccggtctggaaccgctgaccatcgacgccagcaccctg
ttcgtcaacgtcggcgagcgcaccaacgtcaccggttcggcgcgattcaaacgcctgatc
aaagaagaaaaatacaacgaggcgctcgacgtggcgcgccagcaggtcgagagcggcgcg
cagatcatcgatatcaacatggacgaggggatgctcgacgccgaagcggcgatggtgcgt
ttcctcaacctgatcgccggcgagccggatatcgcccgggtgccgatcatgatcgactcc
tccaagtggtccgttatcgagaaaggcctgaaatgcattcagggcaagggcatcgtcaac
tcgatctcgatgaaggagggcgaagaggcctttatccaccacgcccggctggtgcgccgc
tatggcgccgcggtggtggtgatggcgttcgacgaagtgggccaggcggacacccgcgag
cgcaagttcgagatctgtcgccgcgcctataaaattttgaccgaacgcgtcggtttcccg
ccggaagacatcattttcgacccgaacatcttcgccgtcgccaccggcatcgaagagcac
aacaactacgccgtcgactttatcgaagcctgcgccgacatcaaaacccatctgccacac
gcgatgatctccggcggggtgtccaacgtgtcgttctcgttccgcggcaacgatccggtg
cgcgaggcgatccacgcggtgttcctgtatcacgccattcgcaatggcatggacatgggc
atcgtcaacgccgggcaactggcgatttatgacgatctgcctggcgagctgcgcgaggcg
gtagaggacgtgatcctcaaccgtcgcgaggacggcaccgaacgcctgctggagctggcg
gaaaagtaccgcggcagcaaagacggcgaagcggcggtgcagcaggcggagtggcgcggc
tggccggtggaaaagcggctggagtattcgctggtgaagggcatcaccgagtttatcgag
ttggacaccgaagaggcgcggcagcaggccgaacggccgatcgaagtgattgaagggccg
ctgatggcggggatgaacgtggtcggcgatctgttcggcgagggcaagatgttcctgccg
caggtggtgaaatccgcccgcgtgatgaagcaggcggtggcctacctggaaccgtacatc
gaggccagcaagcagcagggcacctccgcggggaaaatcctgctggcgacggtgaagggc
gacgtgcacgacatcggcaagaacatcgtcggcgtggtgctgcagtgcaacaactatgaa
atcgtcgatcttggcgtgatggtgccgacggagaaaatcctgcgcaccgcgcgcgaggag
aacgtcgacatcatcggcctgtcggggctgatcacgccgtcgctcgacgagatggtcaac
gtggccaaagagatggagcgccagggctttaccctgccgctgctgatcggcggcgccacc
acctccaaggcgcacaccgcggtgaaaatcgagcagaactacagcggcccgaccacctac
gtgcaaaacgcctcgcgcaccgtgggcgtggtggcggcgctgctgtccgccacccagcgc
gatgagtttgtggcgcgcacccgcaaagagtatgaaacggtgcgcattcagcacgcgcgc
aaaaaaccgcgcacgccgccggtcgatttgcacaaggcgcgcgccaacgccatggcgctg
gactgggccgactatcagccgccggcgccgcggcagcttggcgtattcccggtgtcggcc
ggcatcgagacgctgcgccactatatcgactggacgccgttcttcatgacctggtcgctg
gcgggcaaatacccgcgcatcctggaagacgaggtggtgggggaagaggccaagcgcctg
ttccacgacgccaatcagatgctggatcggctggccgccgagcgcagcctcaacccgcgc
ggcgtttacggcctgttcccggccaaccgcgtcggcgacgacgtggaagtgtaccgcgac
gaacagcgcagcgaggtgctggcggtgagccgccatctgcgtcagcagacggaaaaaacc
gacttcccgaactactgcctggcggacttcgtggcgccgaaaagcagcggcaaggccgac
tacttcggtgccttcgcggtgaccggcgggctggaggaggacgcgctggcggcggcgtac
gacgcacagcacgacgattacaacaaaatcatggtcaaggcgctggcggatcgtctggcg
gaggctttcgccgaatacctgcacgaacaggtgcgcaagttgcactggggttatgccgcc
gacgagaatctgagcaacgaagaactgatccgcgaaaactatcagggcatccggccggcg
ccgggctacccggcctgcccggagcacaccgaaaaagcgaccatctggcagctgctggac
gtcaaccgccacaccggcatggaactgacggagtccttcgccatgtggccgggggcagcg
gtgtccggctggtacttcagccatcctgagagcaagtacttcgcggtggcgcagatccag
cgcgatcaggtggaagactacgcggcgcgtaaagggatgagcgtgagcgaggtcgaacgc
tggctggcgccaaacctcggctacgacgccgactga

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