Serratia marcescens WW4: SMWW4_v1c47160
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Entry
SMWW4_v1c47160 CDS
T02448
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
smw
Serratia marcescens WW4
Pathway
smw00260
Glycine, serine and threonine metabolism
smw00261
Monobactam biosynthesis
smw00270
Cysteine and methionine metabolism
smw00300
Lysine biosynthesis
smw01100
Metabolic pathways
smw01110
Biosynthesis of secondary metabolites
smw01120
Microbial metabolism in diverse environments
smw01230
Biosynthesis of amino acids
Module
smw_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
smw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
smw_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
smw00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SMWW4_v1c47160 (metL)
00270 Cysteine and methionine metabolism
SMWW4_v1c47160 (metL)
00300 Lysine biosynthesis
SMWW4_v1c47160 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SMWW4_v1c47160 (metL)
Enzymes [BR:
smw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SMWW4_v1c47160 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SMWW4_v1c47160 (metL)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
AGE20503
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Position
complement(5118375..5120810)
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AA seq
811 aa
AA seq
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MNAIAVAGPVSGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPGDMMVVSAAGSTTNQLIN
WLKLSQSDRLSAHQVQQTLRRYHSDLISGLLPPESAEPLIAEFIQDLERLAGLLDGNVDE
VCYAEVVGHGEIWSARLMAAVLNQLDMQAAWLDARDFLRAERAAQPQVDEGRSYPLLQQL
MAQHPGKRLVVTGFISRNDAGETVLLGRNGSDYSATQVGALAGAARVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIE
RVLASGTGAKIVTSHDDVCLIELHVAAQHDFKLAQKELDLVLKRAQIKPLAVGIHPDRNL
VQLCYTSEVVNSALATLQAAALPGELRLREGLALVAMVGAGVCKNPLHSHRFYQQLKDQP
VEFIWQAEDGISLVAVLRQGPTALLIQGLHQSLFRAEKRIGLVLFGKGNIGSRWLELFAR
EQTNISARSGFEFILAGVVDSRRSLLNYDGLDASRALAFFEDEAQELDEESLFLWMRAHP
FDDLVVLDVTASEELAGQYLDFASYGFHVISANKLAGASCSDSYRQIRDAFAKTGRHWLY
NATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQYDGTVPFTELVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGCELGSVDQFFENGEALN
QQMQQRFEAASEMGLVLRHVARFDANGKARVGVEAVRPEHPLASLLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLAQLL
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgaatgcaattgctgtagcagggccggtgagcgggcgtcaactgcacaagtttggcggc
agcagtctggcggatgtgaagtgttatctgcgtgtggccgggattatggcggaatacagc
cagccgggcgacatgatggtggtatcggccgccggcagtaccaccaaccagttgatcaac
tggctgaagctcagccagagcgatcgcctgtctgcgcatcaggtgcagcagacgttgcgt
cgctatcacagcgatcttatcagcggcctgttgccgccggaaagcgccgagccgctgatc
gccgagttcattcaggatctggaacgtctggcggggctgctggacggcaacgtcgacgag
gtatgctatgccgaagtggtcgggcacggcgagatctggtcggcgcgcctgatggcggcg
gtgcttaatcagctggatatgcaggcggcctggctggacgcgcgtgatttcctgcgcgcc
gagcgcgccgcgcagccgcaggtggatgaaggccgttcttacccgctgctgcagcaattg
atggctcaacatccgggcaaacgcctggtggtgaccggcttcatttcgcgcaacgacgct
ggggaaaccgtgttgttggggcgtaacggcagcgactactccgccactcaggtcggcgcg
ttggccggcgctgcgcgcgtcaccatctggagcgacgtggccggggtatacagcgccgat
ccgcgcaaggtgaaagacgcctgcttgctgccgctgctgcgtctggacgaagccagcgag
ctggcgcgcctggcggcgccggtattgcacacccgtaccctgcagccggtctccggcagc
gatatcgatcttcagctgcgctgcagctatcagccggagcagggctcgacgcgcatcgag
cgcgtattggcttccggcaccggcgccaagattgtcaccagccacgacgatgtgtgcctg
attgaactgcacgtcgccgctcaacatgacttcaaactggcgcagaaagagttggatctg
gtgctcaagcgcgcgcagataaaaccgctggcggtgggcatccaccctgaccgcaacctg
gtgcagctgtgttacacctccgaggtggtcaacagcgcgctggcgacgctgcaggccgcg
gcgctgccaggcgagctgcgcctgcgtgaagggttggcgctggtggcgatggtcggcgcc
ggggtgtgcaagaacccgctgcacagccaccgtttctatcagcagttgaaagatcagccg
gtcgagttcatctggcaggcggaagatggcatcagcctggtggcggtattgcgccagggg
ccgaccgcgctgctgatccaggggctgcaccaaagcctgttccgcgccgagaagcgcatc
ggtctggtgctgttcggcaagggcaatatcggctcgcgctggctggagctgttcgcccgt
gagcagaccaatatctccgcgcgcagcggcttcgaatttatcctggcgggggtggtggac
agccgccgcagcctgctgaactatgacgggctggacgccagccgcgcgctggcattcttt
gaggacgaagcgcaggagctggatgaagaatcgctgttcctgtggatgcgcgcgcacccg
ttcgacgatctggtggtgcttgacgtgaccgccagcgaagagctggccgggcagtatctg
gatttcgccagctacggtttccacgtgatcagcgccaacaagttggcgggggcctcgtgc
agcgacagctatcgccaaattcgcgacgccttcgccaaaaccggccgccactggctgtat
aacgccaccgtcggcgccggcctgccggtcaaccacacggtgcgcgatctgcgcgacagc
ggcgacagcattctggcgatcagcggcatcttctccggcacgctctcctggctgttcctg
cagtatgacggcacggtgccgttcaccgagctggtggatcaggcctggcagcaggggctg
accgaaccggatccgcgggtcgatctctccggccaggacgtgatgcgcaagctggtgatc
ctggcgcgcgaagcgggctacgacatcgaaccgaaccaggtgcgggtcgagtcgctggtg
ccggcgggctgcgagctgggctctgtcgatcagttcttcgagaacggtgaggcgctgaac
cagcagatgcagcagcgctttgaggccgccagcgaaatgggcctggtgctgcgccacgtg
gcgcgtttcgacgccaacggcaaggcgcgggtcggcgtggaggcggtgcgccctgagcat
cctctggcctcgctgctgccgtgcgacaacgtgttcgccatcgaaagccgctggtatcgc
gataatccgctggtgatccgcgggccgggcgccggccgcgacgtcaccgccggcgcgatc
cagtcagaccttaaccgattggcgcagctgctttaa
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