Streptomyces nigrescens: HEK616_13080
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Entry
HEK616_13080 CDS
T08756
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
snig
Streptomyces nigrescens
Pathway
snig00010
Glycolysis / Gluconeogenesis
snig00020
Citrate cycle (TCA cycle)
snig00620
Pyruvate metabolism
snig00785
Lipoic acid metabolism
snig01100
Metabolic pathways
snig01110
Biosynthesis of secondary metabolites
snig01120
Microbial metabolism in diverse environments
snig01200
Carbon metabolism
snig01210
2-Oxocarboxylic acid metabolism
Module
snig_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
snig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HEK616_13080
00020 Citrate cycle (TCA cycle)
HEK616_13080
00620 Pyruvate metabolism
HEK616_13080
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEK616_13080
Enzymes [BR:
snig01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HEK616_13080
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transket_pyr
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
BDM67821
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Position
complement(1484456..1487179)
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AA seq
907 aa
AA seq
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MPDPVRLPYSQLDQLPDRDPEETAEWRESLDAVTKAAGPHRAAYLMRRTLEQSGLALPQL
LESDYLNTIPTAAEPAVPGDEAMEARIAAWNRWNAAAMVSRGAKYGVGGHIATFASAAWL
YETGFNHFFRGKEAGGTSRSSGAENGGGSGDQLYIQGHAAPGIYARAFLDGRLTEEHLDH
FRREAGGKGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDVSDSHV
WAFLGDGEMDEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRG
AGWNVVKTLWGTAWDELFRLDTTGALARRLREVPDAQFQTYATRDAAYIRDHFFGAEPAL
VEMAKLLSDDKILECFHLSRGGHEARKVYAAYKAAVEHKGAPTVILAQTVKGFTLGKGFE
SKNANHQMKKLTVDEFKVMRDLLELPISDSDFTDGQVPYGHPGADSPEVRYLQERRAELG
GPAPARRSHPLAPLPAPADKAFAAFDKGSGNQSVATTMAFVRLVKDLIRDKQTGKRWVPI
VPDEARTFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGSMADF
IAAATAYATHGETMIPFYIFYSMFGWQRTADQMWQLGDQLGKGFLVGATAGRTTLTGEGL
QHADGHSPMIASTNPAALTYDPAFAYEVAAIVKDGLRRMYGETAPGEDPNVFYYLTVYNE
PMPQPAKPAGVDEGIVRGLYRFNTAATAGVPVPADAPGIQLLASGTAIHWALKAQQLLAE
EWGVAADVWSATSWTELRRDALAADEATLRGEQRTPYVREALSGVETPVLAVSDYMRQVP
DQIAQWVEQDYSSLGADGFGLSDTREAARRHFGVDAESLVVAALAQLARRGDVPASAVKE
ARERYGF
NT seq
2724 nt
NT seq
+upstream
nt +downstream
nt
atgcccgaccccgtgcgcctgccgtacagccagctcgaccagctcccggaccgcgacccc
gaggagacggccgagtggcgcgagtcgctcgacgccgtcaccaaggcggcgggcccgcat
cgcgccgcctacctgatgcgccgcaccctggagcagtcggggctcgcgctcccccagctc
ctggagagcgactacctcaacaccatccccaccgccgccgagcccgccgtgccgggtgac
gaggcgatggaagcccggatcgccgcctggaaccgctggaacgcggccgcgatggtctcc
cgcggcgccaagtacggcgtcggcggccacatcgcgaccttcgcgtccgcggcctggctc
tacgagaccggcttcaaccacttcttccgcggcaaggaggctgggggcacctcccgttcg
agcggagccgagaatgggggaggcagcggcgaccagctctacatccagggccacgccgcg
cccggcatctacgcccgcgccttcctcgacggccgcctcaccgaggagcacctcgaccac
ttccgccgcgaggccggcggcaagggcctgccgtcctacccgcacccgcggcggctgccc
tggctgtgggagttcccgacggtgtcgatgggcctcggcccgctgtcggccatctaccag
gcgcgcttcaaccgctacctgaccaaccgcggcatcaaggacgtctccgactcgcacgtc
tgggcgttcctgggcgacggcgagatggacgagccggagtcgaccgcggcactcgcgctc
gcctcccgtgagggcctggacaacctcaccttcgtcatcaactgcaacctgcagcgcctg
gacggcccggtccgcgccaacttcaagatcgtgcaggagctggaggcccagttccgcggc
gccggctggaacgtcgtcaagacgctgtggggcaccgcctgggacgagctcttccggctc
gacaccaccggcgcgctggcccgccggctgcgcgaggtgccggacgcccagttccagacc
tacgcgacccgcgacgcggcctacatacgcgaccacttcttcggcgccgagcccgccctc
gtcgagatggccaagctgctctccgacgacaagatcctggagtgcttccacctctcgcgc
ggcggccacgaggcgcgcaaggtgtacgcggcgtacaaggcggccgtggagcacaagggc
gcgccgaccgtgatcctcgcgcagacggtcaagggcttcaccctcggcaagggcttcgag
tccaagaacgccaaccaccagatgaagaagctgaccgtggacgagttcaaggtcatgcgc
gacctgctcgaactccccatctccgacagcgacttcaccgacggccaggtcccctacggc
cacccgggcgccgactcccccgaggtccgctacctccaggagcgccgcgcggagctgggc
ggcccggccccggcccgccgctcccacccgctcgcgccgctgccggccccggccgacaag
gccttcgccgccttcgacaagggctccggcaaccagtccgtggccacgaccatggccttc
gtccgcctggtcaaggacctcatccgcgacaagcagaccggcaagcgctgggtgccgatc
gtccccgacgaggcccgcaccttcggcatggagtcgctcttcccgtcgctcgggatctac
tcccccaagggccagacgtacgagccggtcgaccgcgaccagctgatgtactacaaggaa
gccaaggacggccagatcctcaacgagggcatcaccgaggccggttcgatggcggacttc
atcgccgccgccaccgcgtacgccacgcacggcgagacgatgatccccttctacatcttc
tactcgatgttcggctggcagcgcaccgccgaccagatgtggcagctcggcgaccagctc
ggcaagggcttcctggtcggcgccacggccggccgcaccacgctgaccggtgagggcctg
cagcacgcggacggccactcgccgatgatcgcgtcgaccaacccggcggcgctgacgtac
gacccggcgttcgcgtacgaggtcgcggcgatcgtcaaggacggcctgcgccgcatgtac
ggcgagaccgcccccggcgaggacccgaacgtcttctactacctcacggtctacaacgag
ccgatgccgcagccggccaagccggcgggcgtcgacgagggcatcgtccgcggcctgtac
cgcttcaacaccgcggccacggcgggcgttccggtgcccgccgacgccccggggatccag
ctgctggcctccggcaccgcgatccactgggcactcaaggcccagcagctgctcgccgag
gagtggggcgtggccgccgacgtgtggtccgcgacctcctggacggagctgcggcgcgac
gcgctggcggccgacgaggccacgctgcgcggcgagcagcgcacgccgtacgtccgcgag
gcgctcagcggcgtcgagacgccggtcctggccgtcagcgactacatgcgccaggtcccg
gaccagatcgcgcagtgggtcgagcaggactactcctccctcggggcggacggcttcggc
ctgtccgacacgcgtgaggcggcccgccgccacttcggcgtcgacgccgagtcgctcgtg
gtcgcggccctggcccagctcgcccgccgcggcgacgtcccggcctccgcggtcaaggag
gcccgggagcgctacggcttctga
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