Streptomyces nigrescens: HEK616_57710
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Entry
HEK616_57710 CDS
T08756
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
snig
Streptomyces nigrescens
Pathway
snig00020
Citrate cycle (TCA cycle)
snig00630
Glyoxylate and dicarboxylate metabolism
snig00785
Lipoic acid metabolism
snig01100
Metabolic pathways
snig01110
Biosynthesis of secondary metabolites
snig01120
Microbial metabolism in diverse environments
snig01200
Carbon metabolism
snig01210
2-Oxocarboxylic acid metabolism
Module
snig_M00009
Citrate cycle (TCA cycle, Krebs cycle)
snig_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
snig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
HEK616_57710 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
HEK616_57710 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEK616_57710 (kgd)
Enzymes [BR:
snig01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
HEK616_57710 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
HEK616_57710 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
HEK616_57710 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
HEK616_57710 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BDM72284
LinkDB
All DBs
Position
6373798..6377610
Genome browser
AA seq
1270 aa
AA seq
DB search
MSLQSPNTSSISNEADQAGQGKSPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADY
KPGGATAPSTPAEAPAPAGAAPAQSSPAAPAADGPKPAAAPATPAASAPAPTEPAPAKAA
AEPAAAKPAPKPAAAKPAAAKADGEAPAAGPEFVTLRGPSAAVAKNMNASLELPTATSVR
AVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVQALKAMPSMNYSFAQKDGKPTLV
KPEHVNLGLAIDLVKPNGERQLVVAAIKKAETLSFFEFWQAYEDIVRRARDNKLTMDDFT
GVTASLTNPGGIGTVHSVPRLMPGQSMIMGVGAMDYPAEFQGTSQDALNKMGISKVMTLT
STYDHRVIQGAASGEFLRIMSQLLLGENDFYDEIFKSLRIPYEPIRWMRDIDASHDDDVT
KAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFSGKS
MMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERQHKSPEREEQLRILRRLNS
AEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLAN
IVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAV
DPVVEGVARAKQDIINKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVH
VVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNK
DVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQAL
QDFQGQLEKVFTEVRDATTAPAAPEVPQPKAEFPVFVDTAISQEVVKRIAESQVNIPEHI
TVHPRLLPQLQRRAAQIEDNAIDWGMGETLAVGSLLMEGTAVRLAGQDSRRGTFGQRHAV
LIDRETGEDYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPEALVMWEAQFGDF
VNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVA
MPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKTEEFTSGGFRPVIGDSTVK
PEDVRKVVFCSGKVYYDLDAERQKRGADDTAIVRIERLYPLPGKELQAEIAKFPNAEKYL
WAQEEPANQGAWPFLGLNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQ
AQLVAEVFDA
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacacttcgagcatctcgaacgaggccgatcaagcggggcag
ggcaagagccctgctgctgccttcggccccaatgagtggctcgtcgacgagatctaccag
cagtacctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactac
aagccgggcggcgccaccgcgccgagcacgccggcggaggcccccgcccccgccggggcc
gccccggcccagtcgtcccccgcggccccggccgcggacgggccgaagcccgccgccgcg
ccggccaccccggccgcgagcgccccggcccccaccgagcccgcgccggccaaggccgcc
gccgagcccgccgccgcgaagcccgcgccgaagccggccgccgcgaagccggccgccgcg
aaggccgacggcgaggccccggccgccggtcccgagttcgtcaccctgcgcggcccgtcg
gccgccgttgcgaagaacatgaacgcctccctggagctgccgacggccacgtccgtccgc
gcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctcaagcgc
gcccggggcgggaaggtctccttcacccacctcatcgggtacgcgatggtgcaggccctc
aaggccatgccgtcgatgaactactccttcgcgcagaaggacggcaagccgaccctggtc
aagcccgagcacgtcaacctcggcctggccatcgacctggtgaagccgaacggcgagcgc
cagctggtcgtcgccgcgatcaagaaggccgagacgctctcgttcttcgagttctggcag
gcctacgaggacatcgtccgccgggcccgggacaacaagctgacgatggacgacttcacc
ggagtcaccgcgtcgctgaccaaccccggcggcatcggcacggtccactccgtgccgcgc
ctgatgcccggccagtcgatgatcatgggcgtcggcgcgatggactaccccgccgagttc
cagggcacctcgcaggacgccctgaacaagatgggcatctccaaggtcatgacgctgacc
agcacctatgaccaccgcgtgatccagggcgccgcctccggcgagttcctgcgcatcatg
agccagctgctgctcggcgagaacgacttctacgacgagatcttcaagtcgctgcggatc
ccctacgagccgatccgctggatgcgcgacatcgacgcgtcgcacgacgacgacgtcacc
aaggccgcccgggtcttcgagctgatccactcctaccgggtccgcggccacgtcatggcc
gacaccgacccgctggagtaccaccagcgcaagcaccccgacctggacatcaccgagcac
ggcctcaccctgtgggacctggagcgggagttcgcggtcggcggcttctccggcaagtcc
atgatgaagctgcgcgacatcctgggcgtgctgcgcgactcgtactgccgcaccaccggc
atcgagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgggtcgag
cgtcagcacaagtcgcccgagcgcgaggagcagctgcgcatcctgcgccggctgaactcc
gccgaggcgttcgagacgttcctgcagaccaagtacgtcggccagaagcgcttctcgctg
gagggcggcgagtccgtcatcccgctgctggacgcggtcatcgactccgcggccgagtcg
cggctggacgaggtcgtcatcggcatggcccaccgcggccgcctcaacgtcctcgccaac
atcgtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaag
tcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggt
ctggacggcgagcagatcaaggtctcgctgaccgccaacccctcccacctggaggccgtg
gacccggtcgtcgagggtgtcgcgcgcgccaagcaggacatcatcaacaagggcggcacg
gacttcaccgtcctgccgatccagctgcacggtgacgccgcgttcgccggccagggcgtg
gtcgccgagacgctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtgcac
gtcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcgtcgcgctcctccatg
tacgccaccgacgtggcccgcatgatcgaggcgccgatcttccacgtgaacggtgacgac
cccgaggccgtcgtccgcgtcgcccgtctggccttcgagttccgccaggcgttcaacaag
gacgtggtcatcgacctcatctgctaccgccgccgcggccacaacgagtcggacaacccg
gccttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctc
tacaccgagtcgctgatcggccgtggtgacatcaccctcgaagaggcggagcaggcgctc
caggacttccagggacagctggagaaggtcttcaccgaggtccgcgacgccacgacggct
ccggccgcccccgaggtgccgcagcccaaggcggagttcccggtcttcgtcgacaccgcg
atctcccaggaggtcgtcaagcggatcgccgagtcgcaggtcaacatccccgagcacatc
accgtgcacccgcgtctgctgccccagctgcagcgccgcgcggcccagatcgaggacaac
gccatcgactggggcatgggcgagaccctcgccgtcggttcgctgctgatggagggcacc
gcggtccggctcgccggccaggactcccgccgcggtacgttcggccagcggcacgcggtg
ctcatcgaccgcgagaccggcgaggactacaccccgctgctctacctctccgaggaccag
gcccgcttcaacgtctacgactcgctgctgagcgagtacgcggcgatgggcttcgagtac
ggctactcgctggcccgccccgaggcgctggtcatgtgggaggcccagttcggtgacttc
gtcaacggcgcgcagaccgtcgtcgacgagttcatctcctcggccgagcagaagtggggc
cagacctccggcgtcaccctcctcctgccgcacggctacgagggccagggcccggaccac
tcctcggcccggatcgagcggttcctgcagctctgcgcgcagaacaacatgaccgtggcg
atgccgacgctgccctccaactacttccacctgctgcgctggcaggtgcacaacccgcac
cacaagccgctcatcgtcttcaccccgaagtcgatgctgcgtctgaaggccgcggcgtcg
aagacggaggagttcacctcgggcggcttccgcccggtgatcggcgactccacggtcaag
cccgaggacgtccgcaaggtcgtcttctgctccggcaaggtctactacgacctggacgcc
gagcggcagaagcggggcgcggacgacaccgcgatcgtccgcatcgagcggctctacccg
ctgcccggcaaggagctccaggcggagatcgccaagttcccgaacgccgagaagtacctg
tgggcgcaggaagagccggcgaaccagggtgcctggccgttcctcggcctcaacctgatc
gaccacctcgacctggcggtcggtgccgacgtcccgcacggcgagcggctgcggcgcatc
tcgcgcccgcactcctcgtccccggccgtcggctccgccaagcgccaccaggccgagcag
gcccagctggtcgcggaggtcttcgacgcgtag
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