KEGG   Sphaerotilus sulfidivorans: EWH46_04705
Entry
EWH46_04705       CDS       T06182                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
snn  Sphaerotilus sulfidivorans
Pathway
snn00270  Cysteine and methionine metabolism
snn00450  Selenocompound metabolism
snn00670  One carbon pool by folate
snn01100  Metabolic pathways
snn01110  Biosynthesis of secondary metabolites
snn01230  Biosynthesis of amino acids
snn04980  Cobalamin transport and metabolism
snn04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:snn00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    EWH46_04705 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    EWH46_04705 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    EWH46_04705 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    EWH46_04705 (metH)
   04980 Cobalamin transport and metabolism
    EWH46_04705 (metH)
Enzymes [BR:snn01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     EWH46_04705 (metH)
SSDB
Motif
Pfam: Met_synt_B12 Pterin_bind B12-binding_2 B12-binding MtrH Hera_RBD
Other DBs
NCBI-ProteinID: QEN00149
UniProt: A0A5C1PZJ8
LinkDB
Position
complement(995337..998081)
AA seq 914 aa
MNTSLTPPPMRLSGLEPVEIGQGSLFVNVGERTNVTGSRVFAKMILAGEYEKALAVARQQ
VENGAQIIDINMDEAMLDSKAAMVRFLNLIAGEPEIARVPVMIDSSKWEVIEAGLKCIQG
KGVVNSISLKEGEAEFRRQATRVRRYGAAAVVMAFDEKGQADTFQRKIEICERAYRVLVD
EVGFPPEDIIFDPNIFAIATGIEEHDNYAVDFIEATRWIKQNLPGAKVSGGVSNVSFSFR
GNEPVREAIHTVFLYHAIQAGMDMGIVNAGMVGVYDDLEPELRERVEDVVLNRRKDAGER
LIEIADRAKSAGKDESARLAWRGTPEQPAPVEQRLSHALVHGITDFIEADTEEAWQAIRA
RGGRPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLLPYIEAEKKALQ
DAGGDVKPKGKIVIATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCQDILRKAKEEG
ADIIGLSGLITPSLEEMQYVAAEMQRDPYFAERATPLLIGGATCSRVHTAVKIAPNFSGP
VVYVPDASRAVGVCSDLLSEERAPQYIAELKADYDRVREQHANKKATPMVTLAEARANKT
PLDWATYTPPAPKFLGRREFRNQDLAELAACIDWAPFFQTWDLAGKYPDILSDEVVGEQA
TRVLADGRRMLQRLIDGRWLQASGVMGFWPANTVDDDTIEIYADESRSQVLMRWQPLRMQ
TVRPVIDGVARPNRSLADFIAPKGTKPDYIGLFAVTAGLNVEKKEAQFLSEHDDYSAIML
KALADRLAEAFAERLHQRVRTELWGYAADEALSNEQLIAEAYRGIRPAPGYPACPDHLVK
RAMFEVLDAPAIGMGLTESLAMTPAASVSGFYLAHPQATYFNVGRIGEDQLADYAARAGL
DLADARRALAPVLG
NT seq 2745 nt   +upstreamnt  +downstreamnt
atgaacacctccctcaccccgccgccgatgcgcctgtcgggcctggagccggtcgagatc
ggccagggcagcctcttcgtcaacgtcggcgagcgcaccaacgtcaccggcagccgcgtc
ttcgcgaagatgatcctggccggcgagtacgagaaggcgctggccgtcgcgcgccagcag
gtcgagaacggcgcgcagatcatcgacatcaacatggacgaggccatgctcgacagcaag
gccgcgatggtgcgcttcctcaacctgatcgccggcgagccggagatcgcgcgcgtaccg
gtgatgatcgactcctccaagtgggaggtgatcgaggccggcctgaagtgcatccagggc
aagggcgtcgtcaactcgatctcgctgaaggaaggcgaggccgagttcaggcgccaggcc
acgcgggtgcgccgctacggcgccgcggccgtcgtgatggccttcgacgagaagggccag
gccgacaccttccagcgcaagatcgagatctgcgagcgcgcctaccgggtgctggtcgac
gaggtcggctttccccctgaggacatcatcttcgacccgaacatcttcgcgatcgccacc
ggcatcgaggagcatgacaactacgcggtcgacttcatcgaggccacccgctggatcaag
cagaacctgcccggcgccaaggtctcgggcggcgtgtccaacgtctcgttcagcttccgc
ggcaacgagccggtgcgcgaggccatccacacggtgttcctgtaccacgcgatccaggcc
ggcatggacatgggcatcgtcaacgccggcatggtcggcgtctacgacgacctggagccc
gagctgcgcgagcgcgtggaagacgtggtgctcaaccgccgcaaggatgccggcgaacgc
ctgatcgagatcgccgaccgcgccaagagcgccggcaaggacgaatcggcccggctggcc
tggcgcggcacgcctgaacagcccgcgccggtcgagcagcgcctgtcgcacgccctggtg
cacggcatcaccgatttcatcgaggccgacaccgaggaggcctggcaggcgatccgcgcc
cggggcggccgcccgctgcatgtgatcgaaggcccgctgatggccggcatgaacgtggtg
ggcgacctgttcggcgccggcaagatgttcctgccgcaggtggtcaagtcggcccgcgtg
atgaagcaggcggtggcccacctgctgccctacatcgaggccgagaagaaggcgctgcag
gacgccggcggcgacgtgaagcccaagggcaagatcgtcatcgccaccgtcaagggcgat
gtgcacgacatcggcaagaacatcgtcacggtcgtgctgcagtgcaacaacttcgaggtg
gtcaacatgggcgtgatggtcccgtgtcaggacatcctcaggaaggccaaggaggaaggc
gctgacatcatcggcctctccggcctgatcacgcccagcctggaggagatgcaatacgtc
gccgccgagatgcagcgcgacccctacttcgccgagcgggccacgccgctgctgatcggc
ggcgcgacctgctcgcgcgtgcacaccgcggtgaagatcgccccgaacttcagcggcccg
gtggtgtacgtacccgacgcctcgcgcgcggtgggcgtgtgctcggacctgctgagcgag
gagcgcgcgccccagtacatcgccgagctgaaggccgactacgaccgggtgcgcgagcag
cacgccaacaagaaggccacgccaatggtcacgctggccgaggcgcgcgccaacaagacg
ccgctcgactgggccacctacacgccgccggcgccgaaattcctcggccggcgcgagttc
cgcaaccaggatctggccgagctggccgcctgcatcgactgggcgcccttcttccagacc
tgggacctggccggcaagtaccccgacatcctgagcgacgaggtggtcggcgagcaggcc
acccgcgtgctggccgacggccgccggatgctgcagcgcctgatcgacggccgctggctg
caggcaagcggcgtgatgggcttctggccggccaacacggtcgacgacgacaccatcgag
atctacgccgacgagtcgcgcagccaggtgctgatgcgctggcagccgctgcgcatgcag
acggtgcgcccggtgatcgacggcgtggcgcggccgaaccgctcgctggccgacttcatc
gccccgaagggcacgaagccggactacatcggcctgttcgcggtcaccgccggcctgaac
gtcgagaagaaggaggcgcagttcctcagcgaacatgacgactacagcgccatcatgctc
aaggccctggccgaccgcctggccgaagccttcgccgagcggctgcaccagcgggtgcgc
accgagctgtggggctatgcggccgacgaggcgctctccaacgagcagctgatcgccgag
gcctaccgcggcatccgtccggcgcccggctacccggcctgccccgaccacctcgtcaag
cgcgcgatgttcgaggtgctggatgcgccggccatcggcatgggcctgaccgagagcctg
gcgatgacgccggccgcctcggtcagcggcttctatctggcccacccgcaggcgacctac
ttcaacgtcggccgcatcggcgaggaccagctcgccgactacgctgcccgcgccggcctc
gatctggccgacgcgcggcgtgccctggccccggtgctgggctga

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