Streptomyces nodosus: CP978_10530
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Entry
CP978_10530 CDS
T06839
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
snq
Streptomyces nodosus
Pathway
snq00010
Glycolysis / Gluconeogenesis
snq00020
Citrate cycle (TCA cycle)
snq00620
Pyruvate metabolism
snq00785
Lipoic acid metabolism
snq01100
Metabolic pathways
snq01110
Biosynthesis of secondary metabolites
snq01120
Microbial metabolism in diverse environments
snq01200
Carbon metabolism
snq01210
2-Oxocarboxylic acid metabolism
Module
snq_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
snq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP978_10530 (aceE)
00020 Citrate cycle (TCA cycle)
CP978_10530 (aceE)
00620 Pyruvate metabolism
CP978_10530 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP978_10530 (aceE)
Enzymes [BR:
snq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP978_10530 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Motif
Other DBs
NCBI-ProteinID:
QEV38939
UniProt:
A0A0B5DGS3
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Position
2317953..2320655
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AA seq
900 aa
AA seq
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MTDPHAIQPSELDQLPDRDPEETAEWQASLDAVAEAAGPHRAAYLMRRTLERAEGNGIAL
PKLLETDYVNTIPTSAEPAVPGDEALEARITAWNRWNAAAMVTRGSKHGVGGHIATFASA
AWLYEVGFNHFFHGKEGDGSGDQLYIQGHASPGIYARAFLDGRLDETHLDNFRQEAGGSG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTHRGIKDLSSSHVWAFLGDGEM
DEPEAMAAISLAAREELDNLTFVINCNLQRLDGPVRANFKIVQELEGRFRGAGWNVVKSL
WGTAWDELFALDTTGALVRRLREVPDAQLQTYQTRDAAYIRADFFGKEPALAQMAQLLSD
DKILECFHLSRGGHEARKVYAAYRAALAHKGAPTVILAQTVKGFTLGTGFASKNANHQMK
KLTVDEFKTMRDLLELPIPDSDFADGTVPYGRPGADSPEIRYLQERRAALGGPAPARRVH
PVAPLPAPADKAFAAFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAENGQILNEGITEAGSMADFIAAASSYST
HGEPMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLIGATAGRTTLTGEGLQHADGHSPA
IAATNPAALTYDPAFAYEIAVIVKDGLRRMYGQPAPGEDQDVFYYLTVYNEPLPQPAKPA
LQGVDEAIVKGLYRFNTAESAGLSPAANAPRIQLLGSGTAIHWALDAQRLLAEEWGVAAD
VWSATSWGELRRDAMEADAALLRGEDRVPYVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDYTSLGTDGFGLSDTRDAARRHFGVDAQSIVVAALAQLARRGEVQATAVKEARERYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacccccacgccatccagccgagcgagctcgaccagctcccggaccgtgacccg
gaggagaccgccgaatggcaggcctcgctggatgccgtcgccgaggcggcggggccgcat
cgtgcggcgtatctgatgcgtcgcacgctggagcgcgcggagggcaacggcatcgcgctg
ccgaagctcctcgagacggactacgtcaacaccatccccacctccgccgaaccggccgtg
cccggtgacgaggccctggaggcccggatcaccgcgtggaaccgctggaacgcggccgcg
atggtgacccgtggcagcaagcacggcgtcggcggccacatcgccaccttcgcctccgcc
gcctggctctacgaggtcggcttcaaccacttcttccacggcaaggagggggacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgcgttcctc
gacggccgcctggacgagacgcacctggacaacttccgccaggaggccggcggcagcggt
ctgccctcctacccgcacccgcgccggctgccctggctgtgggagttccccaccgtctcc
atgggtctcggcccgctgtcggcgatctaccaggcgcgcttcaaccgctacctcacccac
cgcggcatcaaggacctctcgtcctcgcacgtatgggcgttcctcggcgacggcgagatg
gacgagccggaggccatggcggcgatctcgctggccgcgcgtgaggagctggacaacctc
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttcaag
atcgtgcaggagctggagggccggttccgcggcgccggctggaacgtcgtcaagtcgctc
tggggcaccgcctgggacgagctgttcgcgctcgacaccaccggcgcgctggtccgccgg
ctgcgcgaggtcccggacgcgcagctgcagacgtaccagacccgcgacgccgcctacatc
cgcgcggacttcttcggcaaggagccggcgctcgcccagatggcacagctgctgagcgac
gacaagatcctcgagtgcttccacctctcccgcggtggtcacgaggcgcgcaaggtctat
gccgcgtaccgggcggccctggcgcacaagggcgcgccgacggtcatcctggcccagacg
gtcaagggcttcacgctcggcaccggcttcgcgtccaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaagacgatgcgtgacctgctcgaactccccatccccgac
agcgacttcgccgacggcacggtcccctacggccgcccgggcgccgactcccccgagatc
cgctacctccaggagcgccgcgcggccctcggcggcccggccccggcccgccgcgtccac
ccggtggccccgctgccggccccggccgacaaggcgttcgccgccttcgacaagggctcg
ggctcgcagaacgtcgccaccacgatggcgttcgtccgcctggtcaaggacctggtgcgc
gacaaggagaccgggaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagtcgctgttcccgtcgctcggcatctactcgcccaaggggcagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccgagaacggccagatcctcaacgag
gggatcaccgaggccggttcgatggccgacttcatcgccgcggcgtcgtcgtactcaacg
cacggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctgggccgcggcttcctgatcggcgccacg
gccggccgcaccacgctgaccggtgaaggcctccagcacgccgacggccactcccccgcc
atcgccgcgaccaacccggccgcgctcacctacgacccggcgttcgcctatgagatcgcg
gtgatcgtgaaggacggtctgcgccgtatgtacgggcagccggcgccgggcgaggaccag
gacgtcttctactacctcacggtctacaacgagccgctgccgcagcccgcgaagcccgcg
ctgcagggcgtcgacgaagccatcgtcaagggtctgtaccgcttcaacaccgccgagtcg
gcggggctctcgcccgctgccaacgccccgcgcatccagctgctgggctccggcacggcg
atccactgggcgctcgacgcccagcggctgctcgccgaggagtggggcgtcgcggcggac
gtgtggtcggcgacctcctggggcgagctgcggcgcgacgccatggaggcggacgcggcg
ctgctgcgcggcgaggaccgggtgccctacgtccgtcaggcgctccagggcgccgagggc
ccggtgctcgcggtctcggactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactacacctcgctgggtaccgacggcttcggtctgtcggacacccgtgacgcg
gcccgccgccacttcggcgtcgacgcccagtcgatcgtcgtcgcggccctggcccagctc
gcccggcgcggcgaggtccaggccacggccgtgaaggaggcgcgggagcgctacggcctg
taa
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