Streptomyces nodosus: CP978_11425
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Entry
CP978_11425 CDS
T06839
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
snq
Streptomyces nodosus
Pathway
snq00010
Glycolysis / Gluconeogenesis
snq00020
Citrate cycle (TCA cycle)
snq00620
Pyruvate metabolism
snq00785
Lipoic acid metabolism
snq01100
Metabolic pathways
snq01110
Biosynthesis of secondary metabolites
snq01120
Microbial metabolism in diverse environments
snq01200
Carbon metabolism
snq01210
2-Oxocarboxylic acid metabolism
Module
snq_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
snq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP978_11425 (aceE)
00020 Citrate cycle (TCA cycle)
CP978_11425 (aceE)
00620 Pyruvate metabolism
CP978_11425 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP978_11425 (aceE)
Enzymes [BR:
snq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP978_11425 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
QEV39088
UniProt:
A0A0B5DJB3
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Position
2512297..2515044
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AA seq
915 aa
AA seq
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MASASDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDQRGRERARYLMLRLIEHAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAYLLDRLSERHLDGFRQ
EKSKAPYGLSSYPHPRSMPDFWEFPTVSMGLGSIGAIYQARMNRYMHARGIADTSRSHVW
AFLGDGEMDEPESLGQLSLAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESVFRGA
GWNVIKLIWDRTWDPLLAQDRDGILVNKMNITPDGQFQTYATESGAYIRDHFFGDDHRLR
AMVENMTDAQILHLGRGGHDHRKVYAAFKAAVEHQGQPTVILAKTVKGWTLGPNFEGRNA
THQMKKLTVADLKHFRDRLHLPISDHALESGPPPYYHPGRDSEEIQYMHDRRRLHGGYVP
TRVVRSKPLQLPDDKAYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGRRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKESPTGQMLHDGISEAGCTASMIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLTRGFALGATAGRTTLTGEGLQHADG
HSQLLSSTNPACVAYDPAYSYEIAHIVQDGLRRMYGSSPEHPHGEDVFYYLTVYNEPIRH
PAEPEDVDVEGILRGIHRIAEGTSGAVPAQIMASGVAVPWALQAQRILAEEWQVRADVWS
ATSWNELRREAVDCERHNLLHPEEEERVPYVTRKLSGAEGPFVAVSDWMRSVPDQIARWV
PGAYQSLGADGFGFADTRGAARRFFHIDAQSIVVAVLAELAKAGRVDRSVLKQALDRYQL
LDVTAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttcggcatccgatcgcaatccgatcatcatcggcggcctcccgagtcaggttccg
gacttcgaccccgaggaaacccaggagtggctcgattccctcgacgccgccgtggaccag
cggggccgtgagcgagcccgctatctgatgctccgtctgatcgagcacgcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactatgtgaacaccatcgccaccaaggac
gagccgttcttcccgggcaacgaggagatcgagcgcaagatcctgaacgccacccggtgg
aacgccgccgtgatggtctcccgcgcccagcgtcccggcatcggggtcggcgggcacatc
gccaccttcgcctcctccgcctcgctgtacgacgtggggttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccaggtcttcttccagggccatgcctcgccgggcatc
tatgcgcgcgcctacctcctggaccggctcagcgagcgtcacctggacgggttccgccag
gagaagtccaaggcaccatacggcctctccagctatccgcacccgcgttcgatgccggac
ttctgggagttccccaccgtctccatgggcctcggctcgatcggcgcgatctaccaggcc
cggatgaaccgctatatgcatgcccgcggcatcgcggacacctcccggtcgcatgtgtgg
gccttcctcggcgacggggagatggacgagccggagtcgctgggccagctcagcctcgcc
gcccgtgagggcctggacaatctgaccttcgtggtcaactgcaatctgcagcgcctggac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcggtcttccggggcgcc
ggctggaatgtgatcaaactgatctgggaccgcacctgggacccgctgctggcgcaggac
cgggacggaatcctggtcaacaagatgaacatcactccggacggccagttccagacctat
gcgacggagtccggcgcctacatccgggaccacttcttcggcgacgaccaccggctgcgc
gcgatggtcgagaacatgaccgacgcccagatcctgcacctgggccgcggtggccatgac
caccgcaaggtctatgcggccttcaaggcggccgtggagcaccagggccagccgacggtg
atcctggccaagaccgtcaagggctggacgctgggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgcggacctcaagcacttccgggaccgcctgcat
ctgccgatctccgaccacgccctcgagtccggcccgccgccgtactaccacccggggcgg
gactcggaggagatccagtacatgcacgaccgccgcaggttgcacggcgggtatgtaccg
acccgtgtggtgcggtccaagcccttgcagctgcccgacgacaaggcgtacgccacggtc
aagaaggggtcgggccagcagtccatcgccaccaccatggcgttcgtcaggctgctgaag
gacctcatgcgggacaaggagatcggcaggcggttcgtgctgatcgcgcccgacgagtac
cgcaccttcggaatggactcgttcttcccgagcgccaagatctacaacccgctcggccag
cagtacgagtcggtcgaccgggatctgctgctcgcctacaaggagtcgccgaccggtcag
atgctgcacgacggcatctccgaggcgggctgcacggcgtcgatgatcgcggccggttcg
gcgtacgccacccatggcgagccgctgatcccggtctatgtcttctactcgatgttcggt
ttccagcgcaccggtgaccagttctggcagatggccgaccagctgacccggggattcgcc
ctgggcgcgaccgccggccgtacgaccctgaccggtgagggcctgcagcacgcggacggc
cactcgcagctgctgtcctccaccaacccggcgtgcgtggcctacgacccggcgtactcc
tacgagatcgcgcacatcgtgcaggacgggctgcgccggatgtacggctcctcgcccgag
catccgcacggcgaggacgtcttctactacctcaccgtctacaacgagcccatccggcac
cccgccgagccggaggacgtggacgtcgagggcatcctcaggggcatccaccgcatcgcc
gagggcacctcgggcgccgtcccggcacagatcatggcctccggcgtcgccgtgccctgg
gcgctccaggcacagcggatcctcgccgaggagtggcaggtgcgggccgacgtctggtcg
gcgacctcctggaacgagctgcggcgcgaggccgtggactgcgagcggcacaatctgctg
caccccgaggaggaggagcgggtcccctatgtgacccgcaagctgagcggcgccgagggt
ccgttcgtggccgtgtccgactggatgcgatcggttccggatcagatcgcgcgctgggta
ccgggggcctatcagtccctgggcgccgacggcttcggattcgcggacacccgcggtgcg
gcgcgccgcttcttccatatcgacgcgcagtcgatcgtggtcgcggtgctcgccgagctg
gccaaggcgggcagggtcgaccgctcggtgctcaagcaggcgctcgaccgctatcagctg
ctcgatgtgacggcggccgacccgggagccgcgggcggcgacgcctga
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