Streptomyces nodosus: CP978_22755
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Entry
CP978_22755 CDS
T06839
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
snq
Streptomyces nodosus
Pathway
snq00020
Citrate cycle (TCA cycle)
snq00630
Glyoxylate and dicarboxylate metabolism
snq00785
Lipoic acid metabolism
snq01100
Metabolic pathways
snq01110
Biosynthesis of secondary metabolites
snq01120
Microbial metabolism in diverse environments
snq01200
Carbon metabolism
snq01210
2-Oxocarboxylic acid metabolism
Module
snq_M00009
Citrate cycle (TCA cycle, Krebs cycle)
snq_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
snq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP978_22755
00630 Glyoxylate and dicarboxylate metabolism
CP978_22755
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP978_22755
Enzymes [BR:
snq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP978_22755
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP978_22755
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP978_22755
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP978_22755
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QEV40993
UniProt:
A0A0B5DQX9
LinkDB
All DBs
Position
complement(5027304..5031131)
Genome browser
AA seq
1275 aa
AA seq
DB search
MSPHSPSPSSSSTDDQAGKNPTAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYRPG
AAASPATAGTAAAGAAETTAPAQTAAAAPAPVVPPAAPVAPQIPDAPAAAAPAQPAAAPA
QPATPARPAAPAPVETAAAPAKPKKDVAVLEAPQGPELVTLRGPSAAVAKNMNASLELPT
ATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPAMNWSFAQKDG
KPTLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLT
MDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISK
VMTLTSTYDHRVIQGAASGEFLRVVAGLLLGENGFYDEIFEALRIPYEPVRWLKDIDASH
DDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDIIEHGLTLWDLERDFAVGG
FAGKSLMKLRDILGVLRDSYCRTTGIEYMHIQDPKQRKWIQDRVERPHSKPEREEQLRIL
RRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVVGMAHRGRL
NVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGADGTFTGLDGEQIKVSLVANPS
HLEAVDPVLEGVSRAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRT
GGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFR
QAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEE
AEQALQDYQGQLEKVFTEVREATSQPAAATAEEPQDGFPVAVGTAVSAEVVKRIAASQVN
IPDHITVHPRLLPQLQRRAAMVEDGTIDWGMGETLAIGSLLLEGVPVRLSGQDSRRGTFG
QRHAVIIDRETGEDYTPLQYLSEDQARYNVYDSLLSEYAAMGFEYGYSLARPDALVMWEA
QFGDFVNGAQTVVDEFVSSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQN
NMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTSGQFRPVIG
DDSVDPAAVRKVVFTAGKVYYDLDAERRKRGATDTAIIRLERLYPLAGAELQAEIKKYPN
AEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADIPAGERLRRISRPHGSSPAVGSAKR
HQAEQEQLMREVFDA
NT seq
3828 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacactcccccagtccttcgagtagctcgaccgacgatcaagccgggaagaac
cccacggccgcgttcggtgccaacgagtggctcgtcgacgagatctatcagcagtacctc
caggacccgaattcggtagaccgtgcctggtgggacttcttcgccgactaccggccgggg
gcggctgcctccccggccacggcgggtaccgcggctgcgggggccgcggagaccaccgcc
ccggcacagaccgcggccgccgcaccggcgcccgtcgtcccgcccgccgcacccgtggcg
ccgcagatcccggacgcaccggccgctgccgctccggcgcagccggccgccgctcccgcg
cagccggccaccccggccaggcctgccgcacccgccccggtcgagaccgccgcggcgccc
gccaagcccaagaaggacgtagccgtgctcgaggcgccccagggccccgaactggtgaca
ctgcgcggcccctcggccgccgtcgcgaagaacatgaacgcctcgctggagctgcccacg
gccacgtccgtgcgcgcggtgccggtcaagctgctcttcgacaaccgcatcgtcatcaac
aaccacctgaagcgcgcccggggcgggaagatctccttcacgcacctgatcggctacgcg
atggtccaggccatcaaggcgatgccggcgatgaactggtcgttcgcgcagaaggacggc
aagcccaccctcgtcaagccggagcacgtcaacctcggcctggccatcgacctggtgaag
ccgaacggcgaccgccagctggtcgtcgcggcgatcaagaaggccgagacgctcaacttc
ttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgtgacggcaagctcacg
atggacgacttcaccggggtgacggtctccctcaccaaccccggcggcctcggcaccgtc
cactcggtcccgcggctgatgcccggacagtcggtgatcatgggcgtcggctccatggac
tacccggccgagttccagggcacctcccaggacacgctgaacaagctcggcatctccaag
gtcatgacgctcacgtcgacctatgaccaccgggtgatccagggcgccgcctccggtgag
ttcctgcgcgtcgtcgcgggcctcctgctcggcgagaacggcttctacgacgagatcttc
gaggcgctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcctcgcac
gacgacgacgtcaccaaggccgcacgggtcttcgagctgatccactcctaccgggtccgc
ggccatgtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctg
gacatcatcgagcacggcctcaccctgtgggacctggagcgcgacttcgccgtcggcggc
ttcgccggcaagtcgctgatgaagctgcgcgacatcctcggtgtgctgcgcgactcgtac
tgccgcaccaccggcatcgagtacatgcacatccaggaccccaagcagcgcaagtggatc
caggaccgggtggagcgcccgcactccaagccggagcgcgaggagcagctgcgcatcctg
cgccgtctgaacgcggcggaggccttcgagaccttcctgcagaccaagtacgtcggccag
aagcgcttctccctggagggcggcgaatcggtcatcccgctgctcgacgcggtgatcgac
agcgcggcggagtcccgtctggacgaggtcgtggtcggcatggcccaccgcggccggctg
aacgtgctggcgaacatcgtcggcaagtcgtacgcccagatcttccgcgagttcgagggc
aatctcgaccccaagtcgatgcacggctccggcgacgtcaagtaccacctgggcgccgac
ggcaccttcacgggcctggacggcgagcagatcaaggtctccctggtcgccaacccctcg
catctggaggcggtggacccggtcctggagggtgtctcccgcgccaagcaggacatcatc
aacaagggcggcacggacttcacggtcctgccggtggcgatccacggcgacgcggccttc
gcgggccagggcgtggtggccgagaccctcaacatgtcgcagctgcgcggttaccgcacc
ggcggcacggtccatgtcgtcatcaacaaccaggtcggcttcacggcggccccggagtcg
tcccgctcctcgatgtacgccaccgatgtggcgcgcatgatcgaggccccgatcttccat
gtgaacggtgacgacccggaggcggtcgtgcgcgtcgcacggctggccttcgagttccgt
caggcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaac
gagtcggacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgc
tcggtgcgcaagctgtacaccgagtcgctgatcggccggggcgacatcaccctggaggag
gccgagcaggcccttcaggactaccagggccagctggagaaggtcttcaccgaggtccgc
gaggccacctcgcagccggccgcggccaccgcggaggagccgcaggacggcttcccggtg
gcggtcggcacggcggtctccgccgaggtcgtcaagcggatcgccgcctcccaggtcaac
atccccgaccacatcaccgtccacccgcgcctgctgccccagctccagcgccgggcggcg
atggtcgaggacggcaccatcgactggggcatgggcgagaccctggcgatcggctcgctg
ctgctcgagggcgtcccggtccggctgtcgggccaggactcgcgccgcggcaccttcggc
cagcgccacgcggtcatcatcgaccgtgagacgggcgaggactacaccccgctgcagtac
ctgtccgaggaccaggcgcgctacaacgtctatgactcgctgctgtccgagtacgcggcg
atgggcttcgagtacggctactcgctggcccgcccggacgcgctggtgatgtgggaggcg
cagttcggcgacttcgtcaacggcgcgcagacggtcgtggacgagttcgtctcgtcggcg
gagcagaagtggggccagacgtccggcgtcaccctcctcctgccgcacggctacgagggc
cagggcccggaccactcgtccgcgcgccccgagcggttcctccagctctgcgcccagaac
aacatgacggtcgcgatgccgaccctgccctcgaactacttccacctcctgcggtggcag
gtgcacaacccgcaccacaagccgctggtggtcttcaccccgaagtcgatgctgcgtctg
aaggccgccgcgtcgaaggcggaggagttcacctcgggccagttccgcccggtcatcggc
gacgactcggtcgacccggccgccgtgcgcaaggtcgtcttcacggcgggcaaggtctac
tacgacctggacgccgagcgccgcaagcgcggtgcgaccgacacggcgatcatccggctg
gagcggctgtacccgctggcgggtgccgagctccaggcggagatcaagaagtaccccaac
gccgagaagtacctgtgggcccaggaggagccggcgaaccagggtgcctggccgttcatc
gccctgaacctcatcgaccacctggacctggcggtcggcgcggacatcccggccggcgag
cgtctgcgtcgcatctcgcggccgcacggctcgtccccggcggtcggttccgcgaagcgg
caccaggccgagcaggagcagctgatgcgtgaggtgttcgacgcgtga
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