Streptomyces nigra: DC008_09305
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Entry
DC008_09305 CDS
T05839
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
snz
Streptomyces nigra
Pathway
snz00010
Glycolysis / Gluconeogenesis
snz00020
Citrate cycle (TCA cycle)
snz00620
Pyruvate metabolism
snz00785
Lipoic acid metabolism
snz01100
Metabolic pathways
snz01110
Biosynthesis of secondary metabolites
snz01120
Microbial metabolism in diverse environments
snz01200
Carbon metabolism
snz01210
2-Oxocarboxylic acid metabolism
Module
snz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
snz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DC008_09305 (aceE)
00020 Citrate cycle (TCA cycle)
DC008_09305 (aceE)
00620 Pyruvate metabolism
DC008_09305 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DC008_09305 (aceE)
Enzymes [BR:
snz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DC008_09305 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
AWE49902
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Position
2005448..2008150
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AA seq
900 aa
AA seq
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MTDPNAIQPSALDQLPDRDPEETAEWQASLDAVAEAAGPHRAAYLMRRTLERAEGTGIAL
PKLLETDYVNTIPTAAEPSAPGDEEMERKITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTEQHLDNFRQEAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTARGVKDVSASHVWAFLGDGEM
DEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVIKTL
WGTAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALAEMAKLLSD
DKILECFHLSRGGHEARKVYAAYKAAVEFKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLSVDEFKAMRDLLELPIKDSDFADGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPAPADKAFAAFDKGSGSQNVATTMAFVRLVKDLVRDKETGRRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTSYAT
HGETMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAAIVKDGLRRMYGEAAPGEDQDVFYYLTVYNEPLPQPAKPA
VDGVDQGIVKGLYRFNTAESAGLSPAANAPRIQLLGSGTAIHWALKAQRLLAEEWGVAAD
VWSATSWTELRRDALEADAALLRGEERVPYVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTRDAARRHFGVDAESIVVAALAQLARRGEVKATAVKEAREKYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgcgctcgaccagctccccgaccgtgacccg
gaggagaccgccgagtggcaggcctcgctggacgcggtcgccgaggcggccggcccgcac
cgtgcggcgtacctgatgcgccgcaccctggagcgggccgagggcaccggcatcgcgctg
cccaagctcctcgagacggactacgtcaacaccatccccaccgccgccgagccgtccgcg
cccggtgacgaggagatggagcggaagatcaccgcgtggaaccgctggaacgcggccgcg
atggtgacccgcggctccaagtacggcgtgggcggtcacatcgccaccttcgcctccgcc
gcgtggctctacgagaccggcttcaaccacttcttcaagggcaaggagggcgacggcagc
ggcgaccagctctacatccagggccacgcctcgccgggcatctacgcccgcgccttcctc
gacggccgcctcaccgagcagcacctggacaacttccgccaggaggcgggcggcaacggc
ctgccgtcgtacccgcacccgcgccggctgccctggctgtgggagttcccgaccgtctcc
atgggtctcggcccgctgtcggcgatctaccaggcccgcttcaaccgctatctgacggcc
cgcggcgtcaaggacgtctccgcgtcccacgtatgggccttcctcggcgacggcgagatg
gacgagccggagtcgacggcggcactcgccctggcctcccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaatttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtgatcaagacgctg
tggggcaccgcctgggacgagctgttccagctcgacaccacgggcgcgctggtccgccgg
ctgcgcgaggtgccggacgcgcaggtgcagacgtaccagacgcgcgacgccgcctacatc
cgcgaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctgagcgac
gacaagatcctcgagtgtttccacctctcgcgcggtggccacgaggcccgcaaggtgtac
gccgcctacaaggccgccgtcgagttcaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctctcggtggacgagttcaaggcgatgcgcgacctgctcgaactgcccatcaaggac
agcgacttcgccgacggcgtggtgccctacggccaccccggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcggcggtcccgccccggcccgccgcgtccac
ccggtggccccgctgccggcccccgccgacaaggcgttcgccgccttcgacaagggctcc
ggctcgcagaacgtcgccaccaccatggcgttcgtccgcctggtcaaggacctggtccgc
gacaaggagaccggcaggcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagagcctcttcccgtccctcggcatctactcgccgaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggcgaagaacgggcagatcctcaacgag
gggatcaccgaggccggttcgatggccgacttcatcgccgcgtcgacgtcgtacgcgacg
cacggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcggacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggcgcgacg
gccggccgcaccacgctgaccggtgagggcctgcagcacgccgacggccactcccccgtc
atcgcggcgaccaacccggcggcgctgacgtacgacccggccttcgcctacgaggtcgcg
gccatcgtcaaggacggtctgcgccggatgtacggcgaggccgccccgggcgaggaccag
gacgtcttctactacctgaccgtctacaacgagccgctgccgcagcccgcgaagcccgcg
gtggacggcgtcgaccagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcg
gccggtctgtccccggcggcgaacgccccgcgcatccagctcctgggctccggcaccgcc
atccactgggcgctgaaggcgcagaggctgctcgccgaggagtggggtgtggccgccgac
gtgtggtccgcgacctcctggacggagctgcgccgtgacgcgctggaggccgacgcggcc
ctgctgcgcggcgaggagcgggtgccgtacgtccgtcaggcgctgcagggcgccgagggc
ccggtgctcgcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactggtcctcgctgggcgccgacggcttcggtctgtccgacacccgtgacgcg
gcccgccgccacttcggggtggacgccgagtcgatcgtcgtcgcggccctggcccagctc
gcccggcgtggcgaggtcaaggccaccgcggtgaaggaagcccgcgagaagtacggcctg
tag
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