Streptomyces pactum: B1H29_12210
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Entry
B1H29_12210 CDS
T07142
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
spac
Streptomyces pactum
Pathway
spac00020
Citrate cycle (TCA cycle)
spac00630
Glyoxylate and dicarboxylate metabolism
spac00785
Lipoic acid metabolism
spac01100
Metabolic pathways
spac01110
Biosynthesis of secondary metabolites
spac01120
Microbial metabolism in diverse environments
spac01200
Carbon metabolism
spac01210
2-Oxocarboxylic acid metabolism
Module
spac_M00009
Citrate cycle (TCA cycle, Krebs cycle)
spac_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
spac00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
B1H29_12210 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
B1H29_12210 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
B1H29_12210 (kgd)
Enzymes [BR:
spac01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
B1H29_12210 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
B1H29_12210 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
B1H29_12210 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
B1H29_12210 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AQS71943
UniProt:
A0A1S6JJK6
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All DBs
Position
3026547..3030374
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AA seq
1275 aa
AA seq
DB search
MSPQSPSNSSISTDTDQAGNAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFAD
YKPGAAAAQSASGAASADSGSAPQAAPAPQAQAPAPARPQAAPQQAAAPAQQAAQPAAAP
AAPAAKPAPAKPAAKPQAKAAAPAKDATAAEAPEGPELVTLRGPAAAVAKNMNASLELPT
ATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYAFGEKDG
KPTLIKPAHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLT
MDDFSGVTVSLTNPGGLGTVHSVPRLMPGQAVIMGVGSMDYPAEFQGTSQDTLNKLGISK
VMTLTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDEIFEALRIPYEPVRWLKDIDASH
DDDVTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGG
FAGKSLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRIERSHTKPEREEQLRIL
RRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRL
NVLANVVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPS
HLEAVDPVLEGVARAKQDIINKGGTDFTVLPVAVHGDAAFAGQGVVAETLNMSQLRGYRT
GGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEACVRVARLAFEFR
QAFNKDVVIDLICYRRRGHNETDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEE
AEQALQDYQGQLEKVFTEVREAASQPAAAEPSDPQAEFPVSVNTAVTAETVKRIAESQVN
IPDHVTVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLEGVPVRLSGQDSQRGTFG
QRHAVLINRETGDEFTPLLYLSEDQARYNVYNSLLSEYAVMGFEYGYSLARPDALVMWEA
QFGDFVNGAQTVVDEFISSAEQKWNQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQN
NMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIG
DDSVEAAAVKKVVFCAGKVYYDLDAERKKRGVTDTAIIRIERLYPLPGAELQAEIAKYPN
AEKYLWTQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKR
HQAEQEQLVREVFEA
NT seq
3828 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcgggcaac
gcgggcaagaaccccgccgccgcgttcggtgccaatgagtggctcgtcgacgagatctat
cagcagtacctccaggatccgaattccgtggaccgagcctggtgggacttcttcgccgac
tacaagccgggagcggccgcggcccagtccgcctccggtgccgcgagcgcggactccggc
agcgccccccaggccgcccccgcgccgcaggcgcaggctcccgccccggctcggccccag
gccgccccccagcaggccgccgcgcccgcacagcaggccgcgcagcccgccgccgccccg
gcggctccggccgcgaagcccgccccggccaagcccgccgccaagccgcaggcgaaggcc
gccgcgcccgccaaggacgccaccgccgccgaggcccccgaggggcccgagctggtgacg
ctgcgcggtcccgccgccgcggtcgcgaagaacatgaacgcctcgctggagctgcccacg
gccacgtccgtgcgcgcggtcccggtgaagctgctgttcgacaaccgcatcgtcatcaac
aaccacctcaagcgcgcccggggcgggaagatctccttcacgcacctgatcggctacgcg
atggtgcaggccatcaaggccatgccctcgatgaactacgcgttcggcgagaaggacggc
aagccgacgctcatcaagccggcacacgtcaacctcggtctcgccatcgacctggtcaag
cccaacggcgaccgccagctcgtcgtcgcggcgatcaagaaggccgagacgctgaacttc
ttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaagctgacg
atggacgacttctccggcgtcacggtctccctgaccaaccccggcggcctcggcaccgtc
cactcggtgccgcgcctgatgcccggccaggccgtcatcatgggcgtcggctcgatggac
taccccgcggagttccagggcaccagccaggacaccctgaacaagctcggcatctcgaag
gtcatgacgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgag
ttcctgcgccaggtcgccaacctcctcctcggcgagaacggcttctacgacgagatcttc
gaggcactgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcctcgcac
gacgacgacgtcaccaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgc
ggccacgtcatggccgacaccgacccgctggagtaccagcagcgcaagcaccccgacctg
gacatcaccgagcacgggctcaccctgtgggacctggagcgcgagttcgcggtcggcggc
ttcgccggcaagtccctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtac
tgccgcaccaccggcgtcgagttcatgcacatccaggaccccaagcagcgcaagtggatc
caggaccgcatcgagcgctcgcacaccaagccggagcgcgaggagcagctccgcatcctg
cgccgcctgaacgccgccgaggcgttcgagacgttcctccagaccaagtacgtcggccag
aagcgcttctccctggagggcggcgagtccgtcatcccgctgctggacgcggtcatcgac
tcggcggccgagtcccgcctggacgaggtcgtcatcggcatggcccaccgcggccggctg
aacgtgctggccaacgtcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggc
aacctcgacccgaagtcgatgcacggctccggtgacgtgaagtaccacctgggcgccgag
ggcaccttcaccggcctggacggcgagcagatcaaggtctcgctggtcgccaacccctcg
cacctggaggcggtggaccctgtcctggagggcgtcgcgcgcgccaagcaggacatcatc
aacaagggcggcacggacttcaccgtcctgcccgtcgcggtccacggcgacgcggccttc
gcgggccagggcgtggtggccgagaccctgaacatgtcgcagttgcgcggctaccgcacc
ggcggcacggtccacgtcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcc
tcgcgctcctcgatgtacgcgacggacgtggcccgcatgatcgaggccccgatcttccac
gtgaacggcgacgacccggaggcctgcgtccgcgtggcgcgcctggccttcgagttccgc
caggcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaac
gagaccgacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgc
tcggtgcgcaagctgtacaccgagtccctcatcggtcgcggcgacatcaccctggaagag
gccgagcaggcgctgcaggactaccagggccagctcgagaaggtcttcaccgaggtgcgc
gaggccgcctcccagccggccgccgccgagccctcggacccgcaggccgagttcccggtc
tccgtgaacaccgcggtcaccgccgagaccgtcaagcggatcgccgagtcccaggtcaac
atccccgaccacgtcaccgtgcacccgcggctgctgccgcagctccagcgccgggcggcg
atggtcgaggacggcacgatcgactggggcatgggcgagaccctcgccgtcggctcgctc
ctcctggagggcgtcccggtccggctgtccggccaggactcgcagcgcgggaccttcggc
cagcggcacgcggtgctcatcaaccgcgagaccggtgacgagttcacgccgctgctgtac
ctgtccgaggaccaggcccggtacaacgtctacaactccctgctctccgagtacgcggtg
atgggcttcgagtacggctactcgctggcccgccccgacgcgctggtgatgtgggaggcg
cagttcggcgacttcgtcaacggcgcccagacggtcgtggacgagttcatctcgtcggcc
gagcagaagtggaaccagacctccggtgtcaccctcctcctgccgcacggctacgagggc
cagggcccggaccactcctcggcccgcccggagcgcttcctgcagctctgcgcgcagaac
aacatgacggtcgcgatgccgaccctgccgtcgaactacttccacctcctgcggtggcag
gtgcacaacccgcaccacaagccgctggtcgtcttcaccccgaagtcgatgctgcgcctc
aaggccgccgcctcgaaggcggaggagttcacaacgggccagttccgcccggtcatcggc
gacgactcggtcgaggcggccgcggtcaagaaggtcgtcttctgcgcgggcaaggtctac
tacgacctcgacgccgagcggaagaagcgcggtgtgacggacacggccatcatccgcatc
gagcgcctgtacccgctgccgggtgccgagctccaggcggagatcgccaagtacccgaac
gccgagaagtacctgtggacccaggaggagccggcgaaccagggtgcctggccgttcatc
gcgctcaacctgatcgaccacctggacctggcggtcggcgccgacgtcccgcacggcgag
cgcctgcgccgcatctcgcgcccgcacggctcctccccggccgtcggttccgccaagcgg
caccaggccgagcaggagcaactggtgcgtgaggtgttcgaggcctga
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