KEGG   Streptomyces paludis: DVK44_04210
Entry
DVK44_04210       CDS       T06964                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
spad  Streptomyces paludis
Pathway
spad00270  Cysteine and methionine metabolism
spad00450  Selenocompound metabolism
spad00670  One carbon pool by folate
spad01100  Metabolic pathways
spad01110  Biosynthesis of secondary metabolites
spad01230  Biosynthesis of amino acids
spad04980  Cobalamin transport and metabolism
spad04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:spad00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    DVK44_04210 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    DVK44_04210 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    DVK44_04210 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    DVK44_04210 (metH)
   04980 Cobalamin transport and metabolism
    DVK44_04210 (metH)
Enzymes [BR:spad01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     DVK44_04210 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: AXG77019
UniProt: A0A345HJZ5
LinkDB
Position
complement(969824..973333)
AA seq 1169 aa
MASSPTPSTDSRTRIDALREALATRVVVADGAMGTMLQAQDPTMEDFQDLEGCNEILNVT
RPDIVRSVHEEYFAVGVDCVETNTFGTNYAALAEYDIEDRVHELSEAGARIAREVADEFT
AATGQQRWVLGSMGPGTKLPTLGHAPYGTLRDAYQQNAEGMIAGGADALLIETTQDLLQT
KAAVLGARRAQRIAGTNLPVICSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATG
PAEMSEHLRYLARHSRIPLSCMPNAGLPVLGKNGAHYPLSAAELADAQETFVREYGLSLV
GGCCGTTPEHLRQVVERVRGADLAERTPHPEPGAASLYQTVPFRQDTSYLAIGERTNANG
SKKFREAMLAGRWDDCVEMARDQIREGAHLLDLCVDYVGRDGVADMAELAGRFATASTLP
IVLDSTELPVLRAGLEKLGGRAVINSVNYEDGDGPESRFTKVTELAVEHGAALIALTIDE
EGQARTVEHKVAIAERLITDLTTKWGVHESDILIDCLTFTICTGQEESRGDGIATIGAIR
ELKRRHPDVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIARLE
EEQVKAAHDLIYDRRAEGYDPLQKLMELFEGVNTKSMKAGRAEELLALPLDERLQRRIID
GEKNGLEADLDEALTSRPALEIVNDTLLAGMKVVGELFGSGQMQLPFVLQSAEVMKTAVA
HLEPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVAAILDA
AEEHRADVIGMSGLLVKSTVIMKENLQELNQRQMAADYPVILGGAALTRAYVEQDLHEIY
EGEVRYARDAFEGLRLMDALIAVKRGVPGAALPELKQRRVRAVTAPVAEERAEEGTVRSD
VSVANPVPTPPFWGTRVVKGIQLKEYASWLDEGALFKGQWGLKEARKGGPSYEELVETEG
RPHLRGWLDRMHTENMLEAAVVYGYFPCVSKGDDLILLRDDGSERTRFTFPRQRRGRRLC
LADFFRPEESGETDVVGLQVVTVGSKIGEATAELFEANSYRDYLELHGLSVQLAEALAEY
WHARVRSELGFAGEDPAEVSDMFALKYRGARFSLGYGACPDLEDRAKIAELLEPERIGVQ
LSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3510 nt   +upstreamnt  +downstreamnt
atggcctcgtcgccgaccccctccaccgacagccggacccgtatcgacgccctgcgcgag
gcgctcgccacccgcgtggtggtcgccgacggggccatgggcaccatgctccaggcccag
gatccgacgatggaggacttccaggatctggagggctgcaacgagatcctgaacgtgaca
cgcccggacatcgtccgctccgtgcacgaagagtatttcgcggtcggcgtcgactgcgtc
gagaccaacaccttcggtaccaactacgccgccctcgccgagtacgacatcgaggaccgg
gtccacgagctgtccgaggccggcgcccggatcgcccgcgaggtggccgacgagttcacc
gccgccaccggacagcagcgctgggtgctcggctccatgggccccggcaccaagctgccc
accctgggccacgccccgtacggcaccctgcgcgacgcctaccagcagaacgccgagggc
atgatcgccggcggcgccgacgcgctgctgatcgagaccacccaggacctgctccagacc
aaggccgccgtcctcggcgcccgccgggcccagcggatcgccggtacgaacctcccggtg
atctgctccgtcacggtggagaccaccggcacgatgctcctcggctccgagatcggcgcg
gccctcaccgccctggagccgctcggcatcgacatgatcgggctcaactgcgccaccggc
cccgccgagatgagcgagcacctgcgctatctcgcccgtcactcccgtatcccgctctcc
tgcatgcccaacgccggcctgcccgtcctcggcaagaacggcgcccactacccgctctcc
gccgccgaactcgccgacgcccaggagaccttcgtccgcgagtacggcctctccctggtc
ggcggctgctgcggtacgacaccggaacacctgcgccaggtcgtcgagcgggtccggggc
gccgacctcgccgagcggaccccgcaccccgagccgggcgccgcctcgctctaccagacc
gtgccgttccgccaggacacctcgtacctcgccatcggtgagcgcaccaacgccaacggc
tcgaagaagttccgcgaggccatgctggccggccgctgggacgactgcgtggagatggcc
cgcgaccagatccgcgagggcgcccatctgctggacctctgcgtcgactacgtcggccgc
gacggcgtcgccgacatggccgagctggccggccgcttcgccaccgcctccaccctgccg
atcgtcctcgactccaccgaactgcccgtcctccgcgccggactggagaagctcggcggc
cgggccgtcatcaactccgtcaactacgaggacggcgacggccccgagtcccgcttcacc
aaggtcaccgaactggccgtcgagcacggcgccgcgctcatcgcgctcaccatcgacgag
gagggccaggcccgtaccgtcgaacacaaggtggccatcgcggagcggctgatcaccgac
ctcaccaccaagtggggcgtgcatgagtcggacatcctcatcgactgcctcaccttcacc
atctgcaccggccaggaggagtcccggggcgacggcatcgccaccatcggcgcgatccgc
gaactcaagcgccgccaccccgatgtgcagaccaccctcggcctctccaacatttccttc
ggactgaacccggcggcccggatcgtcctcaactcggtcttcctggacgagtgcgtcaag
gccggcctggactccgccatcgtgcacgcctccaagatcctgcccatcgcccggctggag
gaggagcaggtcaaggccgcccacgacctgatctacgaccggcgcgccgagggatacgac
ccgctccagaagctcatggagctgttcgagggcgtcaacaccaagtcgatgaaggccggc
cgcgccgaggagctgctcgcgctgccgctggacgagcgcctccagcgccgcatcatcgac
ggcgagaagaacggcctggaggccgacctcgacgaagcgctgaccagcaggcccgcgctg
gagatcgtcaacgacaccctgctcgcgggcatgaaggtcgtcggcgagctgttcggctcc
ggccagatgcagctgccgttcgtcctccagtccgccgaggtcatgaagacggcggtcgcc
cacctcgaaccgcacatggagaagtcggacgacgagggcaagggcaccatcgtgctcgcc
accgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctctccaac
aacggctacaacgtggtcaacctgggcatcaagcagcccgtcgccgccatcctcgacgcg
gccgaggagcaccgcgccgatgtcatcggcatgtcggggctgctggtcaagtccaccgtg
atcatgaaagagaacctccaggagctgaaccagcggcaaatggccgccgactaccccgtg
atcctcggcggcgccgcgctcacccgggcgtatgtcgagcaggacctccacgagatctac
gagggcgaagtccgctacgcccgcgacgcgttcgagggcctgcggctgatggacgccctg
atcgccgtcaagcgcggtgtccccggcgccgccctccccgagctgaagcagcgccgcgtc
agggccgtgaccgccccggtggccgaggagcgcgccgaggagggcacggtccgctcggac
gtctccgtggccaaccccgtccccaccccgccgttctggggcacccgggtggtcaagggc
atccagctcaaggagtacgcctcctggctggacgagggcgcgctcttcaagggccagtgg
ggactgaaggaggcccgcaagggcggacccagctacgaggaactggtcgagaccgagggc
cgcccgcatctgcgcggctggctggaccggatgcacacggagaacatgctggaggccgcc
gtcgtctacggctacttcccctgcgtctccaagggcgacgacctgatcctgctgcgcgac
gacggctccgagcgcacccgcttcaccttcccgcgccagcgccgcggccgccgcctctgc
ctcgcggacttcttccgccccgaggagtccggcgagacggacgtggtcggcctccaggtc
gtcaccgtcggctcgaagatcggcgaggcgaccgccgagctgttcgaggccaactcctac
cgcgactacctcgaactgcacgggctctccgtccagctcgccgaggccctcgccgagtac
tggcacgcccgcgtccgctccgaactgggcttcgccggcgaggacccggccgaggtctcc
gacatgttcgcgctcaagtaccgcggcgcccgcttctcgctcggctacggggcctgcccc
gatctggaggaccgcgccaagatcgcggagctgctggagcccgagcgcatcggagtccag
ctctccgaggagttccagctccacccggagcagtccaccgacgccatcgtgatccaccac
cccgaggcgaagtacttcaacgcccgctga

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