Streptomyces paludis: DVK44_06860
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Entry
DVK44_06860 CDS
T06964
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
spad
Streptomyces paludis
Pathway
spad00010
Glycolysis / Gluconeogenesis
spad00020
Citrate cycle (TCA cycle)
spad00620
Pyruvate metabolism
spad00785
Lipoic acid metabolism
spad01100
Metabolic pathways
spad01110
Biosynthesis of secondary metabolites
spad01120
Microbial metabolism in diverse environments
spad01200
Carbon metabolism
spad01210
2-Oxocarboxylic acid metabolism
Module
spad_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DVK44_06860 (aceE)
00020 Citrate cycle (TCA cycle)
DVK44_06860 (aceE)
00620 Pyruvate metabolism
DVK44_06860 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DVK44_06860 (aceE)
Enzymes [BR:
spad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DVK44_06860 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AXG77461
UniProt:
A0A345HL87
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Position
1578319..1580988
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AA seq
889 aa
AA seq
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MPDPVGKLPSELDQLPDRDTEETAEWAASLDAVTEHAGPHRAAYLMRRTLQHAGSAGVPV
PALLETDYVNTIPTSAEPVFDGDVEMESRITAWNRWNAAAMVTRGARYGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTETDLDHFRQESGGKG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRSIKDTANSHVWAFLGDGEM
DEPESTAALALASREQLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSL
WGSAWDELFALDTTGALVRRLRQVPDAQFQTYATRDVAYIRQHFFGVDPALIELAKLLPD
AKIAECFFTSRGGHEARKVYAAYRAALAHKGAPTVILAQTVKGYTLGAGFESRNANHQMK
KLSGEQFRAMRDLLDLPIPDSKLDESLVPYGHPGADSPEVRYLQERRAELGGPAPARRVH
AVALPEAPDKPFQAVYKGSGKQSVATTMAFVRLMKDLMRDKETGKRWVPIVPDEARTFGM
EALFPSAGIYSPLGQTYDPVDRDQIMYYKEAKDGQILNEGITEAGSMADFIAAATSYATH
GETMIPFYIFYSMFGWQRTGDQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLI
ASTNPASLNYDPAFAYEIAVIVKDGLRRMYGPTPEDVFYYLTVYNEPMPQPAMPEGVEEG
ILKGLYRFKEGTPAAADAPRTQLLASGTAIHWALAAQELLAADWGVTADVWSATSWTELR
RDALEADAALLRGEQRVPYVTRALSGAPGPVLAVSDWMRQVPDQISQWVEQDYTSLGTDG
FGLSDTRDAARRHFGVDAQSIVLAALAQLARRGEVKPEQVAEARARYGL
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
atgcccgaccccgtaggcaaactcccgagcgagctggaccagctcccggaccgtgacacc
gaggagaccgccgaatgggcggcctccctcgacgccgtcaccgaacacgcggggccccac
cgggccgcgtacctgatgcgtcgtaccctccagcacgcgggatcggccggggtcccggtg
ccggcgctgctggagaccgattatgtgaacaccatccccacctccgccgagcccgtcttc
gacggcgatgtggagatggagtcccggatcaccgcctggaaccgctggaacgcggcggcg
atggtcacccgcggcgcccgctacggcgtcggcggtcatatcgccaccttcgcgtcggcc
gcctggctgtacgagacgggcttcaaccacttcttccgcggcaaggagggggacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggctcaccgagaccgacctcgaccacttccgccaggagtccggcggcaagggc
ctgccctcgtacccgcacccgcgccggctgccctggctctgggagttcccgaccgtctcg
atgggtctgggcccgctctccgcgatctaccaggcgcgcttcaaccgctatctgaccaac
cgctccatcaaggacaccgccaactcgcacgtctgggcgttcctgggcgacggcgagatg
gacgagcccgagtcgacggcggccctcgccctcgcctcccgtgagcagctcgacaatctg
accttcgtcatcaactgcaacctccagcggctcgacggtcccgtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgcgggctggaatgtcgtcaagtcgctg
tggggctccgcctgggacgagctgttcgcgctggacaccacgggcgcgctggtacgccgg
ctgcgccaggtcccggacgcccagttccagacgtacgcgacccgtgatgtcgcctacatc
cgccagcacttcttcggcgtcgacccggcgctgatcgagctggcgaagctgctgcccgac
gcgaagatcgccgagtgtttcttcacctcgcgcggtggccacgaggcccgcaaggtgtac
gcggcgtaccgtgcggcgctcgcccacaagggcgcgccgaccgtgatcctcgcgcagacg
gtgaagggctacacgctcggcgccggcttcgagtcgcgcaacgccaaccaccagatgaag
aagctctccggcgagcagttccgcgccatgcgcgacctgctggacctgccgatcccggac
tccaagctggacgagagcctcgtcccgtacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgccgagctgggcggtcccgcgccggcccgccgggtgcac
gcggtggcgctgcccgaggcgcccgacaagccgttccaggcggtctacaagggctccggc
aagcagtccgtggcgacgaccatggcgttcgtccgtctgatgaaggacctgatgcgggac
aaggagaccggcaagcgctgggtccccatcgtcccggacgaggcgcgcaccttcggtatg
gaggcgctgttcccgtcggccggtatctactcgccgctggggcagacgtacgacccggtc
gaccgcgaccagatcatgtactacaaggaggccaaggacggccagatcctcaacgagggg
atcaccgaggccggctccatggccgacttcatcgccgccgccacgtcgtacgcgacgcac
ggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacgggc
gaccagatgtggcagctcgccgaccagctcggcaagggcttcatcgtcggcgccacggcc
ggccgtacgaccctgacgggtgagggcctccagcacgcggacggccactcgcacctgatc
gcgtccaccaacccggcgtcgctcaactacgacccggcgttcgcgtacgagatcgcggtg
atcgtcaaggacggtctgcggcggatgtacgggcccacgcccgaggatgtcttctactac
ctgacggtctacaacgagccgatgccgcagcccgcgatgcccgagggcgtcgaggagggc
atcctcaagggcctgtaccgcttcaaggagggcaccccggccgccgccgacgccccccgt
acccagctgctggcgtccggtacggcgatccactgggccctggcggctcaggagctgctc
gccgccgactggggcgtgacggccgacgtctggtccgccacctcctggaccgagctgcgc
cgggacgcgctggaggccgacgcggcgctgctccgcggcgagcagcgggtgccgtacgtg
acgcgcgcgctgtccggcgcgccgggtccggtgctcgcggtcagcgactggatgcggcag
gtgccggaccagatcagccagtgggtcgagcaggactacacctcgctcggtacggacggc
ttcggcctctccgacacccgcgacgcggcccgccggcacttcggtgtcgacgcgcagtcg
atcgtgctggcggcgctggcgcagctggcccgccggggcgaggtcaagccggagcaggtc
gcggaggcccgggcgcgctacggtctctga
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