Streptomyces paludis: DVK44_24070
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Entry
DVK44_24070 CDS
T06964
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
spad
Streptomyces paludis
Pathway
spad00020
Citrate cycle (TCA cycle)
spad00630
Glyoxylate and dicarboxylate metabolism
spad00785
Lipoic acid metabolism
spad01100
Metabolic pathways
spad01110
Biosynthesis of secondary metabolites
spad01120
Microbial metabolism in diverse environments
spad01200
Carbon metabolism
spad01210
2-Oxocarboxylic acid metabolism
Module
spad_M00009
Citrate cycle (TCA cycle, Krebs cycle)
spad_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
spad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
DVK44_24070
00630 Glyoxylate and dicarboxylate metabolism
DVK44_24070
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DVK44_24070
Enzymes [BR:
spad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
DVK44_24070
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
DVK44_24070
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
DVK44_24070
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
DVK44_24070
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AXG80225
UniProt:
A0A345HU51
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Position
complement(5441338..5445204)
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AA seq
1288 aa
AA seq
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MSSQSPSNASISTDEDGQAKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GTSGTAGKSDDKSAGKPAASGAAGAPVPPVTPPAAAKAPAQAQAPAAPAPVAAAPVQAQA
PAQAPAAPAPAVKPAAAPAPAPVAPAAPAPVAAKPAAVKPAAEAPAGPQYTTLRGPSAAV
AKNMSASLEVPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAM
PSMNYSFTEKDGKPTLVKPEHINFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYE
DIVRRARGNKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGT
SQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRIVSQLLLGESGFYDEIFKALRIPYE
PVRWLKDIDASHDEDVTKPARVFELIHSYRVRGHVMADTDPLDYLQRKHPDLDITEHGLT
LWDLEREFAVGGFAGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWLQDRIERGA
HAKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRL
DEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLD
GEQIKVSLVANPSHLEAVDPVLEGVVRSKQDIINKGGTDFTVLPLALHGDAAFAGQGVVA
ETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPE
AVVRVGRLAFEFRQTFNKDVVIDLICYRRRGHNEGDNPQFTNPQMVRLIDKKRSVRKLYT
ESLIGRGDITLEEAEQALQDFQGQLEKVFAEVREATSHAGPALVPDARAEFPVAVTTAVS
QEVVKRIAESQVNIPDTVTVHPRLMPQMLRRAASVEDGTIDWGMGETLAIGSLLMEGTPV
RLSGQDTRRGTFGQRHAVLVDQGTGEDYTPLQYLTEEQARYNVYDSLLSEYAAMGFEYGY
SLARPDALVMWEAQFGDFVNGAQSVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSS
ARPERFLQMCAQGNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIIFTPKSMLRLKAAASKA
EEFTTGGFRPVIGDEGVDPNAVRKVVFCSGKVYYDLDAERQKRGVTDTAILRVERLYPLP
GAELQAEIAKFPNAAKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISR
PHSSSPAVGSAKRHQAEQQQLVSEVFDA
NT seq
3867 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaacgcgagcatctcgaccgacgaagacgggcaggccaag
aatcctgccgcggccttcggggccaatgaatggcttgtcgacgagatctaccagcagtac
ctccaggatccgaattcggtcgaccgtgcctggtgggacttcttcgccgactacaagccg
ggcacctccggcacggcgggcaagtccgatgacaagtccgccgggaagcccgcggcgagc
ggggccgcgggggccccggtgccgcccgtgaccccgccggccgcggcgaaggccccggcc
caggcgcaggctccggccgcaccggcccccgtcgccgccgcgccggtccaggcccaggca
cccgcgcaggctccggccgcacccgcaccggccgtgaagcccgccgccgcgcccgccccg
gcgcccgtcgccccggccgcgcccgcgcccgtggcggcgaagcccgccgcggtgaagccc
gccgccgaggcgccggccggaccgcagtacacgacgctgcgcggcccgtccgccgccgtc
gcgaagaacatgagcgcctcgctggaggtgcccacggccacctccgtgcgcgccgtcccg
gtgaagctcctcttcgacaaccgcatcgtgatcaacaaccacctgaagcgcgcgcggggc
ggcaagatctccttcacgcacctcatcgggtacgcgatggtgcaggcgatcaaggccatg
ccgtcgatgaactactccttcacggagaaggacggcaagccgaccctggtcaagccggag
cacatcaacttcggtctcgccatcgacctggtgaagcccaacggcgaccgtcagctcgtc
gtcgccggcatcaagaaggccgagacgctcaacttcttcgagttctggcaggcgtacgag
gacatcgtccgccgcgcccgcggcaacaagctgacgatggacgacttcaccggcgtcacc
gtctccctgaccaaccccggcggcctcggcaccgtgcactccgtgccgcgtctgatgccc
ggtcagtcggtcatcatgggcgtcggctcgatggactacccggccgagttccagggcacc
tcgcaggacaccctgaacaagctgggcatctcgaaggtcatgacgctgacctccacgtac
gaccaccgggtcatccagggcgccgcctccggcgagttcctgcggatcgtcagtcagctg
ctgctcggcgagagcgggttctacgacgagatcttcaaggcgctgcgcatcccctacgag
cccgtccgctggctcaaggacatcgacgcgtcgcacgacgaggacgtcaccaagcccgcc
cgggtcttcgagctgatccactcctaccgggtccgcggccatgtcatggccgacaccgac
ccgctggactacctccagcgcaagcaccccgacctcgacatcaccgagcacgggctcacc
ctctgggacctggagcgggagttcgcggtcggcggcttcgccggcaagtcgatgatgaag
ctgcgcgacatcctcggtgtgctgcgcgactcgtactgccgcaccaccggcatcgagttc
atgcacatccaggacccgaagcagcgcaagtggctccaggaccgtatcgagcgcggcgcg
cacgccaagcccgagcgcgaggagcagctgcggatcctgcgcaggctcaacgcggccgag
gcgttcgagacgttcctccagacgaagtacgtcggccagaagcggttctcgctggagggc
ggcgagtccgtcatcccgctgctcgacgcggtcatcgactccgccgccgaatcgcgcctc
gacgaggtcgtcatcggtatggcccaccgcggccggctgaacgtcctggcgaacatcgtc
ggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatg
cacggctccggcgatgtgaagtaccacctgggcgccgagggcaccttcaccggtctggac
ggcgagcagatcaaggtctcgctggtcgccaacccctcgcacctggaggcggtcgacccg
gtcctggagggcgtcgtccgctccaagcaggacatcatcaacaagggcggtacggacttc
acggtgctgccgctcgcgctccacggcgacgcggccttcgcgggccagggcgttgtcgcc
gagacgctcaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtg
atcaacaaccaggtcggcttcaccgccgcgcccgagtcgtcgcgctcctcgatgtacgcc
acggacgtggcccgcatgatcgaggcgccgatcatccatgtgaacggggacgacccggag
gccgtggtccgggtgggccggctcgccttcgagttccgccagacgttcaacaaggacgtc
gtgatcgacctcatctgctaccgccgccgcggtcacaacgagggcgacaacccgcagttc
accaacccgcagatggtccggctgatcgacaagaagcgctcggtgcgcaagctctacacc
gagtcgctgatcggccgcggcgacatcacgctggaagaggcggagcaggcgctccaggac
ttccagggccagctggagaaggtcttcgcggaggtccgcgaggccacctcgcacgccggc
ccggcgctggtccccgacgcccgtgccgagttcccggtggccgtcaccaccgcggtctcg
caggaggtcgtcaagcggatcgccgagtcgcaggtcaacatccccgacacggtcaccgtc
cacccgcgcctgatgccgcagatgctgcgccgcgcggcgtcggtggaggacggcacgatc
gactggggcatgggcgagaccctcgccatcggctcgctgctgatggagggcacccccgtc
cggctctccggccaggacacccgccgcggtacgttcggccagcgccacgcggtcctggtc
gaccagggcaccggcgaggactacaccccgctccagtacctgacggaggagcaggcccgt
tacaacgtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctac
tcgctggcccgcccggacgcgctggtcatgtgggaggcgcagttcggtgacttcgtgaac
ggcgcgcagtcggtcgtggacgagttcatctcgtcggccgagcagaagtggggccagacg
tccggcgtcaccctgctgctgccgcacggctacgagggccagggcccggaccactcgtcc
gcgcgccccgagcgcttcctccagatgtgcgcgcagggcaacatgacggtcgccatgccg
accctgccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcaccacaag
ccgctcatcatcttcaccccgaagtcgatgctgcgtctgaaggccgcggcgtccaaggcg
gaggagttcaccaccggcggcttccgtccggtgatcggtgacgagggcgtggacccgaac
gcggtccgcaaggtcgtcttctgctccggcaaggtctactacgacctcgacgccgagcgg
cagaagcgcggcgtgacggacaccgcgatcctgcgggtggagcggctgtacccgctgccg
ggcgccgaactccaggcggagatcgccaagttcccgaacgcggcgaagtacctgtgggcc
caggaggagccggccaaccagggcgcgtggccgttcatcgcgctcaacctgatcgaccac
ctggacctggcggtcggcgccgacgtcccgcacggcgagcgcctgcgccgcatctcgcgc
ccgcactcctcgtcccccgcggtcggctcggccaagcgccaccaggcggagcagcagcag
ctggtcagcgaggtcttcgacgcctga
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