KEGG   Streptomyces parvulus: Spa2297_06435
Entry
Spa2297_06435     CDS       T04685                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
spav  Streptomyces parvulus
Pathway
spav00270  Cysteine and methionine metabolism
spav00450  Selenocompound metabolism
spav00670  One carbon pool by folate
spav01100  Metabolic pathways
spav01110  Biosynthesis of secondary metabolites
spav01230  Biosynthesis of amino acids
spav04980  Cobalamin transport and metabolism
spav04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:spav00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Spa2297_06435
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Spa2297_06435
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Spa2297_06435
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Spa2297_06435
   04980 Cobalamin transport and metabolism
    Spa2297_06435
Enzymes [BR:spav01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Spa2297_06435
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: ANJ06661
UniProt: A0A191UVA5
LinkDB
Position
complement(1390247..1393759)
AA seq 1170 aa
MASSPSTPPADTRTRVSALREALAGRVVVADGAMGTMLQAQNPSLDDFQQLEGCNEVLNL
TRPDIVRSVHEEYFAVGVDCVETNTFGANHSALGEYDIPERVHELSEAGARVAREVADEF
QARDGRQRWVLGSMGPGTKLPTLGHAPYTVLRDAYQRNAEGLVAGGADALLVETTQDLLQ
TKASVLGARRALDALGLDLPVIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCAT
GPAEMSEHLRYLARHSRIPLSCMPNAGLPVLGKDGAHYPLTAPELADAQETFVREYGLSL
IGGCCGTTPEHLRQVVERVRDTAPGERRPRPEPGAASLYQTVPFRQDTSYLAIGERTNAN
GSKKFREAMLEGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTL
PIVLDSTEVEVVQAGLEKLGGRAVINSVNYEDGDGPESRFARVTTLAREHGAALIALTID
EEGQARTAEKKVEIAERLIDDLTGNWGIHESDILVDCLTFTICTGQEESRGDGIATIEGI
RELKRRHPDVQTTLGLSNISFGLNPAARILLNSVFLDECVKAGLDSAIVHASKILPIARF
DDEQVTTALDLIYDRRGEGYDPLQKLMQLFEGATAKSLKASKAEELAALPLDERLKRRII
DGERNGLEQDLDEALRERPALEIVNETLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAV
AHLEPHMEKTDDDGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILE
AADEHKADVIGMSGLLVKSTVIMKENLEELNQRKLAADYPVILGGAALTRAYVEQDLHEI
YDGEVRYARDAFEGLRLMDALIGIKRGVPGAKLPELKQRRVRAAGIEVEERPEEGHVRSD
VATDNPLPEPPFWGTRVVKGIQLKEYASWLDEGALFKGQWGLKQARTGEGPSYEELVETE
GRPRLRGLLDRLQTENLLEAAVVYGYFPCVSKDDDLIVLDDDGNERTRFSFPRQRRGRRL
CLADFFRPEESGERDVVGFQVVTVGSRIGEETARMFEANAYRDYLELHGLSVQLAEALAE
YWHARVRSELGFGGEDPAEMEDMFALKYRGARFSLGYGACPDLEDRAKIADMLQPERIGV
HLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggcctcgtcgccgtccaccccgcccgccgacacccggacccgcgtgtccgccctccgc
gaggccctcgccggccgcgtcgtggtcgccgacggcgcgatgggcaccatgctccaggcg
cagaacccctcgctggacgacttccagcagctggaggggtgcaacgaggtcctgaacctc
acccggccggacatcgtgcgctcggtgcacgaggagtacttcgccgtcggcgtggactgc
gtggagacgaacaccttcggcgccaaccactcggcgctcggcgagtacgacatccccgag
cgggtccacgagctgtccgaggccggggcccgggtggcccgcgaggtggccgacgagttc
caggcccgcgacggccggcagcgctgggtcctgggctccatgggccccggcaccaagctc
cccaccctcggccacgccccgtacacggtgctgcgcgacgcctaccagcgcaacgccgag
ggcctcgtcgcgggaggcgccgacgcgctcctcgtggagaccacgcaggacctcctccag
accaaggcctcggtcctcggcgcccggcgcgccctcgacgcgctcggcctcgacctgccc
gtgatcgtctccgtgaccgtggagacgaccggcaccatgctgctcggctcggagatcggc
gcggccctcacggcactggaaccgctgggcatcgacatgatcggcctgaactgcgccacc
ggcccggcggagatgagcgagcacctgcgctacctcgcccggcactcccgcatcccgctg
tcctgcatgcccaacgccggactgcccgtcctcggcaaggatggggcgcactacccgctg
acggcgccggagctggcggacgcgcaggagacgttcgtccgcgagtacggcctgtccctg
atcggcggctgctgcggcaccacccccgagcacctgcgccaggtcgtcgagcgggtgcgg
gacacggcacccggcgagcgccggccgcggcccgaaccgggcgccgcctccctctaccag
acggtccccttccggcaggacacctcgtacctggcgatcggcgagcggaccaacgccaac
ggctcgaagaagttccgcgaggccatgctggagggccgctgggacgactgcgtggagatg
gcccgcgaccagatccgcgagggcgcgcacatgctcgacctgtgcgtggactacgtcggc
cgcgacggcgtggccgacatggaggagctggcggggcgcttcgcgaccgcgtcgaccctg
ccgatcgtgctggactccaccgaggtcgaggtcgtccaggccgggctggagaagctcggc
ggccgcgcggtgatcaactccgtgaactacgaggacggcgacggcccggagtcccgcttc
gcgcgggtcacgacgctggcgcgggagcacggtgccgcgctgatcgcgctgaccatcgat
gaggagggccaggcccgcaccgccgagaagaaggtcgagatcgccgagcggctcatcgac
gacctcaccggcaactggggcatccacgagtcggacatcctcgtcgactgcctgaccttc
accatctgcaccggccaggaggagtcccggggggacgggatcgccaccatcgagggcatc
cgggagctgaagcggcggcacccggacgtgcagaccacgctcggcctgtccaacatctcc
ttcggcctcaacccggccgcccgcatcctgctgaactccgtcttcctggacgagtgcgtc
aaggcgggcctggactcggcgatcgtccacgcgtccaagatcctgccgatcgcccggttc
gacgacgagcaggtcaccaccgcgctcgacctgatctacgaccggcgcggcgagggctac
gacccgctgcagaagctgatgcagctcttcgagggtgccaccgccaagtccctcaaggcg
tccaaggccgaggagctcgcggcgctgccgctggacgagcggctcaagcggcgcatcatc
gacggtgagcgcaacggcctggagcaggacctcgacgaagccctccgggagcgtccggcg
ctggagatcgtgaacgagaccctgctggacggcatgaaggtcgtcggcgagctgttcggc
tccggccagatgcagctgccgttcgtgctccagtccgccgaggtcatgaagaccgcggtg
gcgcacctggaaccgcacatggagaagaccgacgacgacggcaagggcaccatcgtgctc
gccacggtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctgtcc
aacaacggctacaacgtcgtcaacctcggcatcaagcagccggtctccgcgatcctggag
gcggccgacgagcacaaggccgacgtcatcggcatgtccgggctcctggtcaagtccacg
gtgatcatgaaggagaacctggaggagctgaaccagcgcaagctggccgccgactacccc
gtcatcctgggcggcgcggccctcacccgggcctacgtcgagcaggacctgcacgagatc
tacgacggcgaggtccgctacgcccgcgacgccttcgagggcctgcgcctgatggacgcg
ctgatcggcatcaagcgcggagtgccgggagccaagctgcccgagctgaagcagcgccgg
gtccgcgcggccggcatcgaggtcgaggagcggcccgaggagggtcacgtccgctccgac
gtcgccaccgacaacccgctgccggagccgccgttctggggcacccgcgtcgtcaagggc
atccagctcaaggagtacgcctcctggctcgacgagggcgcgctgttcaagggccagtgg
ggcctcaagcaggcccgcaccggcgagggcccctcgtacgaggaactggtggagaccgag
ggccggccccggctgcgcgggctcctcgaccggctccagaccgagaacctgctggaggcg
gccgtcgtctacggctacttcccctgcgtctccaaggacgacgacctcatcgtcctcgac
gacgacggcaacgagcgcacccgcttcagcttcccccgccagcgacgcggccggcggctg
tgcctcgccgacttcttccggccggaggagtccggtgagcgggacgtggtcggcttccag
gtcgtgaccgtcggctcccgcatcggcgaggagacggccaggatgttcgaggccaacgcc
taccgcgactacctcgaactgcacgggctgtccgtgcagctcgccgaggccctcgccgag
tactggcacgcgcgcgtgcgctccgagctgggcttcggcggggaggatccggccgagatg
gaggacatgttcgccctgaagtaccggggcgcccgcttctccctcggctacggcgcctgc
ccggacctggaggaccgcgccaagatcgccgacatgctgcagccggagcgcatcggcgtg
cacctgtccgaggagttccagctgcaccccgagcagtccaccgacgccatcgtgatccac
cacccggaggccaagtacttcaacgcccgctga

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