Streptomyces parvulus: Spa2297_22305
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Entry
Spa2297_22305 CDS
T04685
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
spav
Streptomyces parvulus
Pathway
spav00020
Citrate cycle (TCA cycle)
spav00630
Glyoxylate and dicarboxylate metabolism
spav00785
Lipoic acid metabolism
spav01100
Metabolic pathways
spav01110
Biosynthesis of secondary metabolites
spav01120
Microbial metabolism in diverse environments
spav01200
Carbon metabolism
spav01210
2-Oxocarboxylic acid metabolism
Module
spav_M00009
Citrate cycle (TCA cycle, Krebs cycle)
spav_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
spav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Spa2297_22305 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
Spa2297_22305 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Spa2297_22305 (kgd)
Enzymes [BR:
spav01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Spa2297_22305 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Spa2297_22305 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Spa2297_22305 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Spa2297_22305 (kgd)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Trypco1
Motif
Other DBs
NCBI-ProteinID:
ANJ09463
UniProt:
A0A191V3I9
LinkDB
All DBs
Position
complement(4882679..4886497)
Genome browser
AA seq
1272 aa
AA seq
DB search
MSPQSPSNSSISTDTDQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAPATPAAAPGATATDAGSAPQAAPAPQAQAPAPAQPKAAPQPAAPAKPAAKPAAAAPAA
KPAQAPAKPAAQPQAKAAAPAKDGKDAAAPEGPEMVTLRGPAAAVAKNMNASLELPTATS
VRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPTMNYAFGEKDGKPT
LVKPAHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDD
FSGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMT
LTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDEIFKALRIPYEPVRWLKDIDASHDDD
VTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFAG
KSLMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERSHTKPEREEQLRILRRL
NAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVVGMAHRGRLNVL
ANVVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLE
AVDPILEGVSRAKQDIIGKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGT
VHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEACVRVARLAFEFRQAF
NKDVVIDLICYRRRGHNETDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQ
ALQDYQGQLEKVFTEVREAASQPASAEPSEPQAEFPVAVTTAVSAETVKRIAESQVNIPD
HITVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLEGVPVRLSGQDSQRGTFGQRH
AVVIDRETGDEFTPLLYLSEDQSRYNVYNSLLSEYAVMGFEYGYSLARPDALVMWEAQFG
DFVNGAQTVVDEFISSAEQKWNQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMT
VAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDDS
VDPAAVKKVVFTAGKVYYDLDAERKKRGVTDTAIIRIERLYPLPGAELQAEIAKYPNAEK
YLWAQEEPANQGAWPFIALNLIDHLDLAVGADIPHGERLRRISRPHGSSPAVGSAKRHQA
EQEQLVREVFEA
NT seq
3819 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcgggcaag
aaccccgccgcggcgttcggtgccaacgagtggctcgttgacgagatctatcagcagtac
ctccaggacccgaattccgtggaccgagcctggtgggacttcttcgccgactacaagccc
ggagcgcccgcgaccccggccgccgcccccggtgccacggccacggacgccggcagcgca
ccgcaggccgcccccgcgccgcaggcgcaggcccccgccccggcgcagccgaaggcggcg
ccccagccggccgcccccgcgaagccggccgccaagcccgccgccgcggctccggccgcg
aagcccgcgcaggcgccggccaagcccgccgcccagccgcaggcgaaggccgccgcgccc
gccaaggacggcaaggacgccgccgcccccgagggccccgagatggtgaccctgcgcggc
cccgccgccgcggtcgcgaagaacatgaacgcctccctggagctgcccacggccacgtcc
gtgcgcgccgtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctc
aagcgcgcccggggcgggaagatctccttcacgcacctgatcggctacgcgatggtgcag
gccatcaaggccatgccgacgatgaactacgcattcggcgagaaggacggcaagccgacc
ctcgtcaagccggcgcacgtcaacctcggcctcgccatcgacctggtcaagcccaacggc
gaccgccagctggtcgtcgcggcgatcaagaaggccgagacgctgaacttcttcgagttc
tggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaagctgacgatggacgac
ttctccggcgtcacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtg
ccccgtctgatgcccggccagtccgtcatcatgggcgtcggctccatggactaccccgcg
gagttccagggcaccagccaggacaccctgaacaagctcggcatctcgaaggtcatgacg
ctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcgc
caggtcgccaacctgctcctcggcgagaacggcttctacgacgagatcttcaaggcgctg
cgcatcccctacgagccggtccgctggctcaaggacatcgacgccagccacgacgacgac
gtcaccaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtc
atggccgacaccgacccgctggagtaccagcagcgcaagcaccccgacctggacatcacc
gagcacgggctcaccctgtgggacctggagcgcgagttcgcggtcggcggcttcgcgggc
aagtccctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcacc
accggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggatccaggaccgc
atcgagcgctcgcacaccaagccggagcgcgaggagcagctgcgcatcctgcgccggctg
aacgcggcggaggccttcgagaccttcctgcagaccaagtacgtcggccagaagcgcttc
tccctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactcggcggcc
gagtcccgcctggacgaggtcgtcgtcggcatggcccaccgcggccggctgaacgtgctg
gccaacgtcgtcggcaagtcgtacgcccagatcttccgcgagttcgagggcaacctcgac
ccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttc
accggcctggacggcgagcagatcaaggtctcgctggtcgccaacccctcgcacctggag
gcggtcgacccgatcctggagggcgtctcgcgcgccaagcaggacatcatcggcaagggc
ggcacggacttcaccgtcctgccggtggcgatccacggcgacgcggccttcgcgggccag
ggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacg
gtccacgtcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgctcc
tcgatgtacgccaccgacgtggcccgcatgatcgaggccccgatcttccacgtgaacggc
gacgacccggaggcctgcgtccgcgtggcgcggctggccttcgagttccgccaggcgttc
aacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagaccgac
aacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgc
aagctctacaccgagtccctcatcggtcgcggcgacatcaccctggaggaggccgagcag
gcgctccaggactaccaggggcagctggagaaggtcttcaccgaggtccgcgaggccgcc
tcgcagcccgcctccgccgaaccgtcggagccgcaggccgagttcccggtcgccgtgacc
accgcggtcagcgccgagacggtcaagcggatcgccgagtcccaggtcaacatccccgac
cacatcaccgtgcacccgcggctgctgccgcagctccagcgccgggcggcgatggtcgag
gacggcacgatcgactggggcatgggcgagaccctcgccgtcggctcgctgctcctggag
ggcgtgccggtccggctctccggccaggactcgcagcgcggcaccttcggccagcgccac
gcggtcgtcatcgaccgcgagacgggcgacgagttcacgccgctgctgtacctgtccgag
gaccagtcccggtacaacgtctacaactcgctgctctccgagtacgcggtgatgggcttc
gagtacggctactcgctggcccgcccggacgcgctggtgatgtgggaggcgcagttcggc
gacttcgtcaacggcgcgcagacggtcgtcgacgagttcatctcgtcggccgagcagaag
tggaaccagacgagcggcgtgacgctcctgctcccgcacggctacgagggccagggcccg
gaccactcctcggcccgcccggagcgcttcctccagctctgcgcgcagaacaacatgacg
gtcgcgatgccgaccctgccgtcgaactacttccacctcctgcggtggcaggtgcacaac
ccgcaccacaagccgctggtcgtcttcaccccgaagtcgatgctgcgcctgaaggccgcg
gcctcgaaggcggaggagttcacgacgggccagttccgcccggtcatcggcgacgactcg
gtcgacccggccgccgtcaagaaggtcgtcttcaccgccggcaaggtctactacgacctc
gacgccgagcggaagaagcgcggcgtgaccgacacggccatcatccgcatcgagcgcctg
tacccgctgccgggtgccgaactccaggcggagatcgccaagtacccgaacgccgagaag
tacctgtgggcccaggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaac
ctgatcgaccacctggacctcgcggtcggcgccgacatcccgcacggcgagcgcctgcgg
cgcatctcgcgcccgcacggctcgtccccggcggtcggctccgccaagcgccaccaggcg
gagcaggagcagctggtgcgtgaggtcttcgaggcctga
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