KEGG   Streptococcus pyogenes MGAS6180 (serotype M28): M28_Spy0669
Entry
M28_Spy0669       CDS       T00263                                 
Symbol
dyr
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
spb  Streptococcus pyogenes MGAS6180 (serotype M28)
Pathway
spb00670  One carbon pool by folate
spb00790  Folate biosynthesis
spb01100  Metabolic pathways
spb01240  Biosynthesis of cofactors
spb04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:spb00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    M28_Spy0669 (dyr)
   00670 One carbon pool by folate
    M28_Spy0669 (dyr)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    M28_Spy0669 (dyr)
Enzymes [BR:spb01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     M28_Spy0669 (dyr)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AAX71782
UniProt: Q48U24
LinkDB
Position
690446..690943
AA seq 165 aa
MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAVLMGRVTFEGMNCKRLPQ
RQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNKVLEAFNGYFDRIIKTV
IHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALKHK
NT seq 498 nt   +upstreamnt  +downstreamnt
atgacaaaggaaattattgctatttgggcagaggatgaagcagggcttattggtgttgcg
ggtaagttaccatggtatttaccaaaagagttagaacattttaaaaagacaacgctacat
caagcagtcttaatgggccgtgtgacttttgaaggaatgaattgcaaaagacttcctcaa
cgtcaaacccttgtcatgacaagaaatagagattatcaagtagatgaggtgttgacaatg
actagtattgaaaaagtcttggagtggtaccatgcgcaggataaaacactttatatcatt
ggtgggaataaggttttagaagcgtttaatggttatttcgatcgtatcataaaaacagtt
atccatcatcgttttaaaggagatacctaccgaccaaatctagattttagtcatttcacg
caagaaagccaaacgttctatgctcgagacgctaaaaatccttatgattttaccgttact
gctttaaaacacaaatag

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