Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy0032
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Entry
MGAS10270_Spy0032 CDS
T00355
Symbol
purK
Name
(GenBank) Phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit
KO
K01589
5-(carboxyamino)imidazole ribonucleotide synthase [EC:
6.3.4.18
]
Organism
sph
Streptococcus pyogenes MGAS10270 (serotype M2)
Pathway
sph00230
Purine metabolism
sph01100
Metabolic pathways
sph01110
Biosynthesis of secondary metabolites
Module
sph_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sph00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS10270_Spy0032 (purK)
Enzymes [BR:
sph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.18 5-(carboxyamino)imidazole ribonucleotide synthase
MGAS10270_Spy0032 (purK)
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Gene cluster
GFIT
Motif
Pfam:
ATP-grasp
RS_preATP-grasp-like
PurK_C
Dala_Dala_lig_C
ATP-grasp_3
2-Hacid_dh_C
CPSase_L_D2
Rossmann-like
3HCDH_N
NAD_binding_2
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
ABF33097
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All DBs
Position
49178..50287
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AA seq
369 aa
AA seq
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MRNKEKSQRSQVVNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPASDCPASRVSEVI
VAPYDDVEALGQLAARCDVLTYEFEDVDADGLDAVVSACQLPQGTDLLRISQNRIFEKDF
LANKAGVTVAPYKVVTSSLDLEGLDLTKTYVLKTATGGYDGHGQKVIRSAEDLPEAQQLA
NSAQCVLEEFVNFDLEISVIVSGNGQDVTVFPVQENIHRNNILSKTIVPARISDQLADKA
KKMAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEACDFSQFDTHILGV
LGAPLPQIQLHAPAVMLNVLGQHVQQATDYVAKNPSAHLHMYGKLEAKHNRKMGHVTVFA
KDADEVKEF
NT seq
1110 nt
NT seq
+upstream
nt +downstream
nt
atgaggaacaaggaaaaatcgcagaggagtcaagtggtgaactcatttaagaccattggg
attatcggtggtggtcagctggggcagatgatggcgattgcggctatctatatgggccac
aaggtcatcacgctggatcctgctagcgactgccctgcctcccgcgttagcgaggtgatt
gtggcgccttacgatgatgttgaggctttgggacaattggctgcgcgttgcgatgtgttg
acttatgagtttgaggatgttgatgcggacggtttggatgccgttgtgtcagcttgtcag
ctaccgcaggggaccgatctgctccgcatttcccaaaaccgtatctttgaaaaagacttt
ctggcaaataaggctggtgtgactgtcgctccctataaggtggtgacgtctagccttgac
ttagaggggcttgatttgaccaagacctatgtcctcaagacagcgacaggtggttatgac
ggtcatgggcaaaaggttattcgctccgcagaagacctaccagaggcgcaacaattagcc
aactcagctcagtgtgtcttggaagagtttgtcaattttgaccttgaaatctcagttatc
gtgtctggaaatggtcaggatgtgacggtctttcccgttcaggaaaatatccaccgcaat
aatatcctgtcaaaaaccatcgtgccagctcgtatctcagatcaactggctgataaggct
aagaaaatggcggtgcagattgccaagaaactccagctgtcaggaactctctgtgtggaa
atgtttgcgaccgcagatgatatcattgtcaatgaaattgccccacgtccccacaactca
gggcactactcaatcgaggcttgcgacttttcacagtttgacacccacattttgggcgtg
ttgggcgcaccacttcctcagattcagctccacgccccagccgtcatgctcaatgtccta
ggacaacatgtccagcaggcaactgactatgttgccaaaaaccctagcgcccacctccac
atgtatggtaaactagaagcgaaacataaccgcaaaatgggacatgtgacggtgtttgca
aaagatgcggatgaggtgaaggagttttaa
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