Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy0745
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Entry
MGAS10270_Spy0745 CDS
T00355
Symbol
mvaS1
Name
(GenBank) Hydroxymethylglutaryl-CoA synthase
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
sph
Streptococcus pyogenes MGAS10270 (serotype M2)
Pathway
sph00280
Valine, leucine and isoleucine degradation
sph00650
Butanoate metabolism
sph00900
Terpenoid backbone biosynthesis
sph01100
Metabolic pathways
sph01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sph00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
MGAS10270_Spy0745 (mvaS1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MGAS10270_Spy0745 (mvaS1)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
MGAS10270_Spy0745 (mvaS1)
Enzymes [BR:
sph01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
MGAS10270_Spy0745 (mvaS1)
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Motif
Pfam:
HMG_CoA_synt_C
Chal_sti_synt_N
ACP_syn_III
DUF1414
PS_Dcarbxylase
Motif
Other DBs
NCBI-ProteinID:
ABF33810
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All DBs
Position
complement(722202..723416)
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AA seq
404 aa
AA seq
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MGKTIKITKRRTNMTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVAPI
TEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFARSFEV
KQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVTTNPR
ILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENLQLSDF
AAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLTEAFQASITYSKQIGNIYTGSLYLGLL
SLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRTRLSVSKY
EDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
atgggtaagactataaaaataactaaaagaaggacaaatatgacaattggaattgataag
attggttttgcaaccagtcaatatgtcttgaaattggaagatttagcgcttgcacgccaa
gtggatccagcaaaatttagtcaagggctactcattgagtcttttagtgtggcaccaatc
actgaagacattattactttagctgcttctgcagcagatcaaattttaaccgatgaagat
cgatctaagattgatatggttattttggcaactgaatcgagtactgatcagtcaaaggca
tcagctatctatgtacatcacttagttggtatccagccttttgcacgttcctttgaagta
aaacaagcctgctatagcgcaactgctgctctagactatgctaaactgcatgtggcttct
aagccagattctcgtgtccttgttattgctagtgatattgctagatacggtgtaggatct
cctggcgaatcaactcaaggctctggtagtattgctcttttggtaactactaaccctcgt
attcttgctctaaataaagataatgtggctcaaactagggatattatggacttttggagg
cctaactatagtttcacaccttatgttgatggtatttactctaccaagcaatatctcaat
tgcttagaaaccacgtggcaagcttatcagaaaagagaaaaccttcagttatctgatttt
gctgcagtttgtttccatattccatttcccaagttagccctaaaaggtctaaataacatt
atggataacacagtacctcctgaacacagggaaaaactaacagaagcctttcaagcttct
attacttatagcaaacaaattggaaatatttatactggctcactttatctaggattgtta
tctttacttgaaaatagtaaagtattacaatctggagataaaattggtttttttagctat
ggttccggtgccgtaagtgaattttattccggtcagttagttgctgggtacgataaaatg
ttaatgactaatcgacaagctttactagatcaacgaacacgtctttccgtttctaaatac
gaagaccttttctacgaacaagtccaattagatgataatggtaatgccaattttgacatt
tacttaactggaaaatttgctctaacagccatcaaggagcatcaaaggatctatcatacc
aatgacaaaaactaa
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