Streptomyces phaeolivaceus: F9278_11285
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Entry
F9278_11285 CDS
T07107
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sphv
Streptomyces phaeolivaceus
Pathway
sphv00010
Glycolysis / Gluconeogenesis
sphv00020
Citrate cycle (TCA cycle)
sphv00620
Pyruvate metabolism
sphv00785
Lipoic acid metabolism
sphv01100
Metabolic pathways
sphv01110
Biosynthesis of secondary metabolites
sphv01120
Microbial metabolism in diverse environments
sphv01200
Carbon metabolism
sphv01210
2-Oxocarboxylic acid metabolism
Module
sphv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sphv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
F9278_11285 (aceE)
00020 Citrate cycle (TCA cycle)
F9278_11285 (aceE)
00620 Pyruvate metabolism
F9278_11285 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F9278_11285 (aceE)
Enzymes [BR:
sphv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
F9278_11285 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
QFQ96712
UniProt:
A0A5P8K1Q2
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Position
2403886..2406588
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AA seq
900 aa
AA seq
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MTDPNAIQPSALDQLPDRDPEETAEWQASLDAVTKAAGPHRAAYLMRRTLERAEGNGIAL
PKLLETDYVNTIPTAAEPAVPGDEALERRITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFKGKEADGSGDQLYIQGHASPGIYARAFLDGRLNESHLDNFRRESAGDG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTSRGIKDVSNSHVWAFLGDGEM
DEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSL
WGSAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGKDPALVELAKLLSD
DKILECFHLSRGGHEARKVYAAYKAAVEFKGAPTVILAQTVKGFTLGEGFASKNANHQMK
KLSTDEFKQMRDLLELPIKDSDFVDGVVPYGHPGADSAEVRYLQERRAALGGPAPARRTH
ALAPLPAAADKTFASFDKGSGSQNVATTMAFVRLVKDLVRDKQTGRRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGSMADFIAASTSYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAVIVKDGLRRMYGEAAPGEDPNVFYYLTVYNEPLPQPAKPG
VAGVDEGIVKGLYRFNTAESAGLSPVANAPRVQLLGSGTAIHWALEAQKLLAEEWGVAAD
VWSATSWSELRRDALDADAALLRGEERVPYVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDYSSLGADGFGLSDTREAARRHFGVDAQSVVVAALAQLARRGEVKATAVKEARERYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgcgctcgaccagctccccgaccgtgatccg
gaggagaccgccgaatggcaggcctcgctggacgccgtcaccaaggcggccgggccgcac
cgcgcggcgtacctgatgcgccgcaccctggagcgtgcggagggcaacggcatcgcgctg
cccaagctgctcgagacggactacgtcaacaccatccccaccgccgccgagccggccgtc
cccggtgacgaggcgctggagcgccgtatcaccgcgtggaaccgctggaacgccgccgcg
atggtgacccgtggctccaagtacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttcaaaggcaaagaggccgacggctcg
ggcgaccagctctacatccagggccacgcctcccccggtatctacgcccgcgccttcctc
gacggccgcctgaacgagtcgcacctcgacaacttccgccgcgagtccgccggcgacggc
ctcccgtcgtacccgcacccgcgccgccttccctggctgtgggagttcccgacggtgagc
atgggcctcggccccctctccgccatctaccaggcgcgcttcaaccgctatctcaccagc
cgcggcatcaaggacgtctcgaactcgcacgtctgggcgttcctcggcgacggcgagatg
gacgagccggagtccacggcggcactcgccctggcctcccgtgagggtctcgacaacctc
accttcgtcatcaactgcaacctccagcgcctcgacggcccggtccgcgcgaacttcaag
atcgtgcaggagctggaggcccagttccggggcgccggctggaacgtggtcaagtcgctg
tggggctccgcctgggacgagctgttccagctcgacaccacgggcgcgctggtccgccgc
ctccgcgaggtgccggacgcgcaggtgcagacgtaccagacccgggacgccgcctacatc
cgccaggacttcttcggcaaggacccggcgctcgtcgagctggcgaagctgctgagcgac
gacaagatcctggagtgtttccacctctcgcgcggtggtcacgaggcgcgcaaggtgtac
gccgcgtacaaggccgccgtcgagttcaagggcgcgccgaccgtcatcctggcgcagacc
gtcaagggcttcaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgtcgacggacgagttcaagcagatgcgtgatctgctcgaactccccatcaaggac
agcgacttcgtcgacggggtggtgccctacggccacccgggcgccgactccgccgaggtc
cgctacctccaggagcgccgcgccgccctcggcggtcccgccccggcccgccgtacgcac
gcgctggcgcccctcccggccgccgccgacaagaccttcgcctccttcgacaagggctcc
ggctcccagaacgtggcgacgaccatggccttcgtccgcctggtcaaggacctggtccgc
gacaagcagaccggccgccgctgggtgccgatcgtccccgacgaggcccgcaccttcggc
atggagagcctcttcccgtccctcgggatctactcccccaagggccagacgtacgagccg
gtcgaccgtgaccagctgatgtactacaaggaggccaaggacgggcagatcctcaacgag
gggatcaccgaggccggttccatggccgacttcatcgccgcctcgacgtcgtacgcgacg
cacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctggcagcggacc
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggcgccacg
gccggccgtacgacgctgacgggcgagggcctgcagcacgccgacggccactctccggtg
atcgcggcgacgaacccggcggcgctgacgtacgacccggcgttcgcgtacgaggtcgcg
gtgatcgtgaaggacggtctgcgccgtatgtacggcgaggccgcgcccggcgaggacccg
aacgtcttctactacctgaccgtgtacaacgagccgctgccgcagcccgcgaagccgggc
gtggccggggtggacgagggcatcgtcaagggcctgtaccgcttcaacacggccgagtcg
gcgggcctgtccccggtggcgaacgcgccgcgcgtgcagctgctcggctccggtacggcg
atccactgggccctggaggcgcagaagctgctcgcggaggagtggggggtggcggccgat
gtctggtcggcgacctcctggagcgaactgcggcgggacgcgctggacgcggacgcggcg
ctgctgcgcggcgaggagcgggtgccgtacgtccggcaggcgctccagggtgcggagggg
ccggtgctggcggtctccgactacatgcggcaggtgccggaccagatcgcgcagtgggtg
gagcaggactactcctcgctgggtgcggacggtttcggcctctccgacacccgtgaggcc
gcgcgtcgtcacttcggggtcgacgcgcagtccgtggtcgtcgcggcgctcgcgcagctt
gcccggcgtggtgaggtcaaggcgacggcggtgaaggaagcgcgggagcggtacgggctg
tag
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